| Full name: gem nuclear organelle associated protein 5 | Alias Symbol: | ||
| Type: protein-coding gene | Cytoband: 5q33.2 | ||
| Entrez ID: 25929 | HGNC ID: HGNC:20043 | Ensembl Gene: ENSG00000082516 | OMIM ID: 607005 |
| Drug and gene relationship at DGIdb | |||
Screen Evidence:
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Expression of GEMIN5:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | GEMIN5 | 25929 | 225712_at | 0.6721 | 0.0608 | |
| GSE26886 | GEMIN5 | 25929 | 225712_at | 0.5940 | 0.0003 | |
| GSE45670 | GEMIN5 | 25929 | 225712_at | 0.2084 | 0.1859 | |
| GSE53622 | GEMIN5 | 25929 | 117542 | 0.0796 | 0.2833 | |
| GSE53624 | GEMIN5 | 25929 | 117542 | 0.4707 | 0.0000 | |
| GSE63941 | GEMIN5 | 25929 | 225712_at | 0.4779 | 0.2341 | |
| GSE77861 | GEMIN5 | 25929 | 225712_at | 0.2137 | 0.3232 | |
| GSE97050 | GEMIN5 | 25929 | A_23_P336513 | 0.1721 | 0.5268 | |
| SRP007169 | GEMIN5 | 25929 | RNAseq | 0.5669 | 0.2247 | |
| SRP008496 | GEMIN5 | 25929 | RNAseq | 0.5807 | 0.0412 | |
| SRP064894 | GEMIN5 | 25929 | RNAseq | 0.2033 | 0.2310 | |
| SRP133303 | GEMIN5 | 25929 | RNAseq | 0.3673 | 0.0179 | |
| SRP159526 | GEMIN5 | 25929 | RNAseq | 0.3328 | 0.2403 | |
| SRP193095 | GEMIN5 | 25929 | RNAseq | 0.2729 | 0.0067 | |
| SRP219564 | GEMIN5 | 25929 | RNAseq | 0.3014 | 0.4299 | |
| TCGA | GEMIN5 | 25929 | RNAseq | 0.0704 | 0.1896 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by GEMIN5 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of GEMIN5:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | GEMIN5 | 25929 | 0 | 12 | 18 | |
| GSE20123 | GEMIN5 | 25929 | 0 | 12 | 18 | |
| GSE43470 | GEMIN5 | 25929 | 2 | 10 | 31 | |
| GSE46452 | GEMIN5 | 25929 | 0 | 27 | 32 | |
| GSE47630 | GEMIN5 | 25929 | 0 | 20 | 20 | |
| GSE54993 | GEMIN5 | 25929 | 9 | 1 | 60 | |
| GSE54994 | GEMIN5 | 25929 | 1 | 16 | 36 | |
| GSE60625 | GEMIN5 | 25929 | 0 | 0 | 11 | |
| GSE74703 | GEMIN5 | 25929 | 2 | 8 | 26 | |
| GSE74704 | GEMIN5 | 25929 | 0 | 7 | 13 | |
| TCGA | GEMIN5 | 25929 | 4 | 38 | 54 |
Total number of gains: 18; Total number of losses: 151; Total Number of normals: 319.
Somatic mutations of GEMIN5:
Generating mutation plots.
Highly correlated genes for GEMIN5:
Showing top 20/884 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| GEMIN5 | SLC25A37 | 0.78776 | 3 | 0 | 3 |
| GEMIN5 | CEP97 | 0.787716 | 3 | 0 | 3 |
| GEMIN5 | PET117 | 0.781441 | 4 | 0 | 4 |
| GEMIN5 | SP3 | 0.773968 | 3 | 0 | 3 |
| GEMIN5 | PLCG1 | 0.772085 | 3 | 0 | 3 |
| GEMIN5 | STK3 | 0.771868 | 4 | 0 | 4 |
| GEMIN5 | DMXL2 | 0.770644 | 3 | 0 | 3 |
| GEMIN5 | ZNF778 | 0.76816 | 3 | 0 | 3 |
| GEMIN5 | PITX2 | 0.761941 | 3 | 0 | 3 |
| GEMIN5 | TP53I13 | 0.76182 | 4 | 0 | 4 |
| GEMIN5 | MRPL36 | 0.756516 | 3 | 0 | 3 |
| GEMIN5 | ZNF689 | 0.754436 | 3 | 0 | 3 |
| GEMIN5 | KLHL13 | 0.752907 | 3 | 0 | 3 |
| GEMIN5 | AHCTF1 | 0.745745 | 4 | 0 | 4 |
| GEMIN5 | MTRR | 0.744809 | 3 | 0 | 3 |
| GEMIN5 | ZBTB2 | 0.741287 | 3 | 0 | 3 |
| GEMIN5 | SFR1 | 0.741106 | 3 | 0 | 3 |
| GEMIN5 | MAP3K2 | 0.738946 | 3 | 0 | 3 |
| GEMIN5 | ZCCHC17 | 0.735087 | 3 | 0 | 3 |
| GEMIN5 | MFHAS1 | 0.734809 | 3 | 0 | 3 |
For details and further investigation, click here
