| Full name: sterile alpha motif domain containing 1 | Alias Symbol: | ||
| Type: protein-coding gene | Cytoband: 19p13.12 | ||
| Entrez ID: 90378 | HGNC ID: HGNC:17958 | Ensembl Gene: ENSG00000141858 | OMIM ID: |
| Drug and gene relationship at DGIdb | |||
Screen Evidence:
| |||
Expression of SAMD1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | SAMD1 | 90378 | 225650_at | 0.5014 | 0.0868 | |
| GSE26886 | SAMD1 | 90378 | 228276_at | 0.2120 | 0.0807 | |
| GSE45670 | SAMD1 | 90378 | 228276_at | 0.0697 | 0.3757 | |
| GSE53622 | SAMD1 | 90378 | 84602 | 0.5476 | 0.0000 | |
| GSE53624 | SAMD1 | 90378 | 84602 | 0.7984 | 0.0000 | |
| GSE63941 | SAMD1 | 90378 | 225650_at | 1.9194 | 0.0002 | |
| GSE77861 | SAMD1 | 90378 | 225650_at | 0.2159 | 0.3796 | |
| GSE97050 | SAMD1 | 90378 | A_23_P435941 | 0.2915 | 0.2969 | |
| SRP007169 | SAMD1 | 90378 | RNAseq | -0.3462 | 0.3112 | |
| SRP008496 | SAMD1 | 90378 | RNAseq | -0.4771 | 0.0180 | |
| SRP064894 | SAMD1 | 90378 | RNAseq | 1.3857 | 0.0000 | |
| SRP133303 | SAMD1 | 90378 | RNAseq | 0.4840 | 0.0034 | |
| SRP159526 | SAMD1 | 90378 | RNAseq | 0.7464 | 0.0186 | |
| SRP193095 | SAMD1 | 90378 | RNAseq | 0.6042 | 0.0000 | |
| SRP219564 | SAMD1 | 90378 | RNAseq | 1.2360 | 0.0420 | |
| TCGA | SAMD1 | 90378 | RNAseq | 0.2494 | 0.0000 |
Upregulated datasets: 3; Downregulated datasets: 0.
Survival by SAMD1 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of SAMD1:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | SAMD1 | 90378 | 4 | 2 | 24 | |
| GSE20123 | SAMD1 | 90378 | 3 | 1 | 26 | |
| GSE43470 | SAMD1 | 90378 | 2 | 6 | 35 | |
| GSE46452 | SAMD1 | 90378 | 47 | 1 | 11 | |
| GSE47630 | SAMD1 | 90378 | 4 | 7 | 29 | |
| GSE54993 | SAMD1 | 90378 | 15 | 4 | 51 | |
| GSE54994 | SAMD1 | 90378 | 6 | 13 | 34 | |
| GSE60625 | SAMD1 | 90378 | 9 | 0 | 2 | |
| GSE74703 | SAMD1 | 90378 | 2 | 4 | 30 | |
| GSE74704 | SAMD1 | 90378 | 0 | 1 | 19 | |
| TCGA | SAMD1 | 90378 | 20 | 11 | 65 |
Total number of gains: 112; Total number of losses: 50; Total Number of normals: 326.
Somatic mutations of SAMD1:
Generating mutation plots.
Highly correlated genes for SAMD1:
Showing top 20/1368 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| SAMD1 | FANCL | 0.837527 | 3 | 0 | 3 |
| SAMD1 | NOSIP | 0.830024 | 3 | 0 | 3 |
| SAMD1 | CHD7 | 0.828808 | 3 | 0 | 3 |
| SAMD1 | SLC39A3 | 0.796488 | 3 | 0 | 3 |
| SAMD1 | PTCD1 | 0.790646 | 3 | 0 | 3 |
| SAMD1 | TMEM54 | 0.78978 | 3 | 0 | 3 |
| SAMD1 | UBQLN4 | 0.788645 | 3 | 0 | 3 |
| SAMD1 | TFDP2 | 0.781381 | 3 | 0 | 3 |
| SAMD1 | BORA | 0.779986 | 3 | 0 | 3 |
| SAMD1 | SNAI3 | 0.77455 | 3 | 0 | 3 |
| SAMD1 | TKT | 0.773893 | 3 | 0 | 3 |
| SAMD1 | MCMBP | 0.773672 | 3 | 0 | 3 |
| SAMD1 | TUBA1B | 0.764513 | 3 | 0 | 3 |
| SAMD1 | TMPO | 0.760487 | 3 | 0 | 3 |
| SAMD1 | SLC11A1 | 0.76047 | 3 | 0 | 3 |
| SAMD1 | CIAO1 | 0.759296 | 4 | 0 | 4 |
| SAMD1 | LRP8 | 0.755736 | 3 | 0 | 3 |
| SAMD1 | MTBP | 0.753061 | 5 | 0 | 5 |
| SAMD1 | INTS8 | 0.752244 | 5 | 0 | 5 |
| SAMD1 | CDCA7 | 0.74887 | 4 | 0 | 3 |
For details and further investigation, click here
