| Full name: U2 snRNP associated SURP domain containing | Alias Symbol: fSAPa|SR140 | ||
| Type: protein-coding gene | Cytoband: 3q23 | ||
| Entrez ID: 23350 | HGNC ID: HGNC:30855 | Ensembl Gene: ENSG00000163714 | OMIM ID: 617849 |
| Drug and gene relationship at DGIdb | |||
Expression of U2SURP:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | U2SURP | 23350 | 212058_at | 1.2064 | 0.0132 | |
| GSE20347 | U2SURP | 23350 | 212058_at | 1.5656 | 0.0000 | |
| GSE23400 | U2SURP | 23350 | 212058_at | 1.4315 | 0.0000 | |
| GSE26886 | U2SURP | 23350 | 212058_at | 1.6985 | 0.0000 | |
| GSE29001 | U2SURP | 23350 | 212058_at | 1.3489 | 0.0004 | |
| GSE38129 | U2SURP | 23350 | 212058_at | 1.3027 | 0.0000 | |
| GSE45670 | U2SURP | 23350 | 212058_at | 0.9958 | 0.0000 | |
| GSE63941 | U2SURP | 23350 | 212058_at | 1.0058 | 0.0165 | |
| GSE77861 | U2SURP | 23350 | 212058_at | 1.2301 | 0.0003 | |
| GSE97050 | U2SURP | 23350 | A_24_P943106 | 0.0538 | 0.8328 | |
| SRP007169 | U2SURP | 23350 | RNAseq | 1.0745 | 0.0040 | |
| SRP008496 | U2SURP | 23350 | RNAseq | 1.2558 | 0.0000 | |
| SRP064894 | U2SURP | 23350 | RNAseq | 0.6249 | 0.0154 | |
| SRP133303 | U2SURP | 23350 | RNAseq | 0.9726 | 0.0000 | |
| SRP159526 | U2SURP | 23350 | RNAseq | 1.0564 | 0.0009 | |
| SRP193095 | U2SURP | 23350 | RNAseq | 0.7356 | 0.0000 | |
| SRP219564 | U2SURP | 23350 | RNAseq | 0.6284 | 0.0208 |
Upregulated datasets: 11; Downregulated datasets: 0.
Copy number change of U2SURP:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | U2SURP | 23350 | 20 | 0 | 10 | |
| GSE20123 | U2SURP | 23350 | 20 | 0 | 10 | |
| GSE43470 | U2SURP | 23350 | 22 | 0 | 21 | |
| GSE46452 | U2SURP | 23350 | 15 | 4 | 40 | |
| GSE47630 | U2SURP | 23350 | 19 | 3 | 18 | |
| GSE54993 | U2SURP | 23350 | 1 | 8 | 61 | |
| GSE54994 | U2SURP | 23350 | 34 | 1 | 18 | |
| GSE60625 | U2SURP | 23350 | 0 | 6 | 5 | |
| GSE74703 | U2SURP | 23350 | 19 | 0 | 17 | |
| GSE74704 | U2SURP | 23350 | 14 | 0 | 6 | |
| TCGA | U2SURP | 23350 | 64 | 3 | 29 |
Total number of gains: 228; Total number of losses: 25; Total Number of normals: 235.
Somatic mutations of U2SURP:
Generating mutation plots.
Highly correlated genes for U2SURP:
Showing top 20/2130 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| U2SURP | LRRC58 | 0.827715 | 5 | 0 | 5 |
| U2SURP | MORC2 | 0.82668 | 9 | 0 | 9 |
| U2SURP | PLXNA1 | 0.826562 | 9 | 0 | 9 |
| U2SURP | ATR | 0.823721 | 10 | 0 | 10 |
| U2SURP | DHX37 | 0.819294 | 4 | 0 | 4 |
| U2SURP | SPRED1 | 0.817707 | 3 | 0 | 3 |
| U2SURP | TOPBP1 | 0.811543 | 10 | 0 | 10 |
| U2SURP | DBN1 | 0.809593 | 3 | 0 | 3 |
| U2SURP | DNAJC2 | 0.809274 | 9 | 0 | 9 |
| U2SURP | YWHAG | 0.805053 | 5 | 0 | 5 |
| U2SURP | C1orf131 | 0.804294 | 5 | 0 | 5 |
| U2SURP | SLC44A1 | 0.803824 | 4 | 0 | 4 |
| U2SURP | SLC41A1 | 0.803708 | 5 | 0 | 5 |
| U2SURP | DDX55 | 0.801236 | 5 | 0 | 5 |
| U2SURP | CMSS1 | 0.800597 | 5 | 0 | 5 |
| U2SURP | ACTL6A | 0.797524 | 10 | 0 | 10 |
| U2SURP | ZNF451 | 0.79553 | 3 | 0 | 3 |
| U2SURP | ACBD6 | 0.793978 | 4 | 0 | 4 |
| U2SURP | HLTF | 0.793316 | 10 | 0 | 9 |
| U2SURP | DHX36 | 0.792071 | 6 | 0 | 6 |
For details and further investigation, click here
