| Full name: ALX homeobox 3 | Alias Symbol: | ||
| Type: protein-coding gene | Cytoband: 1p13.3 | ||
| Entrez ID: 257 | HGNC ID: HGNC:449 | Ensembl Gene: ENSG00000156150 | OMIM ID: 606014 |
| Drug and gene relationship at DGIdb | |||
Expression of ALX3:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | ALX3 | 257 | 207690_at | -0.2299 | 0.3958 | |
| GSE20347 | ALX3 | 257 | 207690_at | -0.1236 | 0.1106 | |
| GSE23400 | ALX3 | 257 | 207690_at | -0.1505 | 0.0000 | |
| GSE26886 | ALX3 | 257 | 207690_at | -0.0195 | 0.8903 | |
| GSE29001 | ALX3 | 257 | 207690_at | 0.0205 | 0.9207 | |
| GSE38129 | ALX3 | 257 | 207690_at | -0.1267 | 0.1123 | |
| GSE45670 | ALX3 | 257 | 207690_at | -0.0922 | 0.4469 | |
| GSE63941 | ALX3 | 257 | 207690_at | 0.2711 | 0.1820 | |
| GSE77861 | ALX3 | 257 | 207690_at | -0.2248 | 0.1787 | |
| GSE97050 | ALX3 | 257 | A_23_P85941 | -0.1703 | 0.5832 | |
| SRP064894 | ALX3 | 257 | RNAseq | 0.3668 | 0.1733 | |
| SRP133303 | ALX3 | 257 | RNAseq | -0.3083 | 0.0867 | |
| SRP159526 | ALX3 | 257 | RNAseq | 0.5487 | 0.3599 | |
| SRP193095 | ALX3 | 257 | RNAseq | 0.0330 | 0.8024 | |
| SRP219564 | ALX3 | 257 | RNAseq | 0.2655 | 0.6867 | |
| TCGA | ALX3 | 257 | RNAseq | -0.0338 | 0.8594 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by ALX3 expression:
 |
| TCGA |
Note: Click image to view full size file.
Copy number change of ALX3:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | ALX3 | 257 | 0 | 12 | 18 | |
| GSE20123 | ALX3 | 257 | 0 | 11 | 19 | |
| GSE43470 | ALX3 | 257 | 0 | 9 | 34 | |
| GSE46452 | ALX3 | 257 | 2 | 1 | 56 | |
| GSE47630 | ALX3 | 257 | 9 | 5 | 26 | |
| GSE54993 | ALX3 | 257 | 0 | 1 | 69 | |
| GSE54994 | ALX3 | 257 | 7 | 4 | 42 | |
| GSE60625 | ALX3 | 257 | 0 | 0 | 11 | |
| GSE74703 | ALX3 | 257 | 0 | 7 | 29 | |
| GSE74704 | ALX3 | 257 | 0 | 7 | 13 | |
| TCGA | ALX3 | 257 | 9 | 27 | 60 |
Total number of gains: 27; Total number of losses: 84; Total Number of normals: 377.
Somatic mutations of ALX3:
Generating mutation plots.
Highly correlated genes for ALX3:
Showing top 20/809 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| ALX3 | JSRP1 | 0.745528 | 4 | 0 | 4 |
| ALX3 | CCR9 | 0.72524 | 3 | 0 | 3 |
| ALX3 | ZMAT4 | 0.71644 | 3 | 0 | 3 |
| ALX3 | TMEM184A | 0.708561 | 4 | 0 | 4 |
| ALX3 | TBX21 | 0.705261 | 3 | 0 | 3 |
| ALX3 | S1PR2 | 0.693383 | 3 | 0 | 3 |
| ALX3 | SLC25A47 | 0.69189 | 4 | 0 | 4 |
| ALX3 | AGRP | 0.690782 | 4 | 0 | 4 |
| ALX3 | ISLR2 | 0.688836 | 3 | 0 | 3 |
| ALX3 | F2RL3 | 0.688014 | 3 | 0 | 3 |
| ALX3 | GRIN2C | 0.684901 | 4 | 0 | 4 |
| ALX3 | RETN | 0.684312 | 3 | 0 | 3 |
| ALX3 | PRAMEF12 | 0.683057 | 3 | 0 | 3 |
| ALX3 | DENND6B | 0.680212 | 3 | 0 | 3 |
| ALX3 | LRRC2 | 0.679633 | 3 | 0 | 3 |
| ALX3 | NCAN | 0.676576 | 4 | 0 | 4 |
| ALX3 | ARPP21 | 0.675754 | 3 | 0 | 3 |
| ALX3 | IGSF21 | 0.675542 | 3 | 0 | 3 |
| ALX3 | SLC22A18AS | 0.673933 | 3 | 0 | 3 |
| ALX3 | INCENP | 0.673633 | 3 | 0 | 3 |
For details and further investigation, click here
