| Full name: PRAME family member 12 | Alias Symbol: OTTHUMG00000001927 | ||
| Type: protein-coding gene | Cytoband: 1p36.21 | ||
| Entrez ID: 390999 | HGNC ID: HGNC:22125 | Ensembl Gene: ENSG00000116726 | OMIM ID: |
| Drug and gene relationship at DGIdb | |||
Expression of PRAMEF12:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | PRAMEF12 | 390999 | 216001_at | -0.0237 | 0.9374 | |
| GSE20347 | PRAMEF12 | 390999 | 216001_at | 0.0740 | 0.4552 | |
| GSE23400 | PRAMEF12 | 390999 | 216001_at | -0.1657 | 0.0019 | |
| GSE26886 | PRAMEF12 | 390999 | 216001_at | -0.3509 | 0.0362 | |
| GSE29001 | PRAMEF12 | 390999 | 216001_at | -0.0515 | 0.7672 | |
| GSE38129 | PRAMEF12 | 390999 | 216001_at | -0.0615 | 0.4785 | |
| GSE45670 | PRAMEF12 | 390999 | 216001_at | -0.0209 | 0.8662 | |
| GSE63941 | PRAMEF12 | 390999 | 216001_at | -0.1055 | 0.6065 | |
| GSE77861 | PRAMEF12 | 390999 | 216001_at | 0.0059 | 0.9627 | |
| GSE97050 | PRAMEF12 | 390999 | A_33_P3418710 | -0.0389 | 0.8707 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by PRAMEF12 expression:
 |
| TCGA |
Note: Click image to view full size file.
Copy number change of PRAMEF12:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | PRAMEF12 | 390999 | 0 | 4 | 26 | |
| GSE20123 | PRAMEF12 | 390999 | 0 | 3 | 27 | |
| GSE43470 | PRAMEF12 | 390999 | 2 | 6 | 35 | |
| GSE46452 | PRAMEF12 | 390999 | 7 | 1 | 51 | |
| GSE47630 | PRAMEF12 | 390999 | 8 | 3 | 29 | |
| GSE54993 | PRAMEF12 | 390999 | 3 | 1 | 66 | |
| GSE54994 | PRAMEF12 | 390999 | 11 | 4 | 38 | |
| GSE60625 | PRAMEF12 | 390999 | 0 | 0 | 11 | |
| GSE74703 | PRAMEF12 | 390999 | 2 | 4 | 30 | |
| GSE74704 | PRAMEF12 | 390999 | 0 | 0 | 20 | |
| TCGA | PRAMEF12 | 390999 | 10 | 22 | 64 |
Total number of gains: 43; Total number of losses: 48; Total Number of normals: 397.
Somatic mutations of PRAMEF12:
Generating mutation plots.
Highly correlated genes for PRAMEF12:
Showing top 20/905 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| PRAMEF12 | SEMA3B | 0.785478 | 3 | 0 | 3 |
| PRAMEF12 | ERN1 | 0.780519 | 4 | 0 | 4 |
| PRAMEF12 | MATN1 | 0.776486 | 4 | 0 | 4 |
| PRAMEF12 | SLC5A4 | 0.775002 | 5 | 0 | 5 |
| PRAMEF12 | MAGEA8 | 0.772098 | 3 | 0 | 3 |
| PRAMEF12 | HCRT | 0.766308 | 3 | 0 | 3 |
| PRAMEF12 | DAB1 | 0.761007 | 5 | 0 | 5 |
| PRAMEF12 | CLCNKB | 0.758013 | 3 | 0 | 3 |
| PRAMEF12 | EFNA2 | 0.757866 | 3 | 0 | 3 |
| PRAMEF12 | SLC9A7 | 0.755823 | 3 | 0 | 3 |
| PRAMEF12 | FERD3L | 0.754509 | 3 | 0 | 3 |
| PRAMEF12 | NCR3 | 0.754341 | 4 | 0 | 3 |
| PRAMEF12 | NTNG1 | 0.75148 | 4 | 0 | 4 |
| PRAMEF12 | ATP2A1 | 0.745571 | 4 | 0 | 4 |
| PRAMEF12 | AIRE | 0.74053 | 5 | 0 | 5 |
| PRAMEF12 | KRTAP9-9 | 0.740088 | 3 | 0 | 3 |
| PRAMEF12 | AQP4 | 0.737073 | 3 | 0 | 3 |
| PRAMEF12 | PTPRN2 | 0.736994 | 4 | 0 | 4 |
| PRAMEF12 | CDH4 | 0.735055 | 3 | 0 | 3 |
| PRAMEF12 | USP29 | 0.732933 | 4 | 0 | 4 |
For details and further investigation, click here
