| Full name: immunoglobin superfamily member 21 | Alias Symbol: MGC15730|RP11-121A23.1 | ||
| Type: protein-coding gene | Cytoband: 1p36.13 | ||
| Entrez ID: 84966 | HGNC ID: HGNC:28246 | Ensembl Gene: ENSG00000117154 | OMIM ID: |
| Drug and gene relationship at DGIdb | |||
Expression of IGSF21:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | IGSF21 | 84966 | 227154_at | -0.1490 | 0.6387 | |
| GSE26886 | IGSF21 | 84966 | 227154_at | 0.6700 | 0.0002 | |
| GSE45670 | IGSF21 | 84966 | 227154_at | -0.0697 | 0.5667 | |
| GSE53622 | IGSF21 | 84966 | 26103 | 0.1671 | 0.3390 | |
| GSE53624 | IGSF21 | 84966 | 26103 | 0.3433 | 0.0315 | |
| GSE63941 | IGSF21 | 84966 | 227154_at | 0.0949 | 0.4870 | |
| GSE77861 | IGSF21 | 84966 | 227154_at | -0.1460 | 0.2505 | |
| GSE97050 | IGSF21 | 84966 | A_32_P78101 | -0.0424 | 0.8503 | |
| SRP159526 | IGSF21 | 84966 | RNAseq | -0.6133 | 0.4037 | |
| SRP219564 | IGSF21 | 84966 | RNAseq | 1.0071 | 0.0070 | |
| TCGA | IGSF21 | 84966 | RNAseq | 0.5034 | 0.1827 |
Upregulated datasets: 1; Downregulated datasets: 0.
Survival by IGSF21 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of IGSF21:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | IGSF21 | 84966 | 0 | 5 | 25 | |
| GSE20123 | IGSF21 | 84966 | 0 | 4 | 26 | |
| GSE43470 | IGSF21 | 84966 | 0 | 8 | 35 | |
| GSE46452 | IGSF21 | 84966 | 5 | 1 | 53 | |
| GSE47630 | IGSF21 | 84966 | 8 | 3 | 29 | |
| GSE54993 | IGSF21 | 84966 | 3 | 1 | 66 | |
| GSE54994 | IGSF21 | 84966 | 10 | 4 | 39 | |
| GSE60625 | IGSF21 | 84966 | 0 | 0 | 11 | |
| GSE74703 | IGSF21 | 84966 | 0 | 5 | 31 | |
| GSE74704 | IGSF21 | 84966 | 0 | 0 | 20 | |
| TCGA | IGSF21 | 84966 | 11 | 23 | 62 |
Total number of gains: 37; Total number of losses: 54; Total Number of normals: 397.
Somatic mutations of IGSF21:
Generating mutation plots.
Highly correlated genes for IGSF21:
Showing top 20/102 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| IGSF21 | SPNS3 | 0.764917 | 3 | 0 | 3 |
| IGSF21 | GALR2 | 0.763816 | 3 | 0 | 3 |
| IGSF21 | AMN | 0.760208 | 3 | 0 | 3 |
| IGSF21 | KCNT1 | 0.755201 | 3 | 0 | 3 |
| IGSF21 | ENHO | 0.750934 | 3 | 0 | 3 |
| IGSF21 | FUT7 | 0.750119 | 3 | 0 | 3 |
| IGSF21 | USHBP1 | 0.7464 | 3 | 0 | 3 |
| IGSF21 | EBF4 | 0.736376 | 3 | 0 | 3 |
| IGSF21 | CHRD | 0.726247 | 4 | 0 | 4 |
| IGSF21 | RGL4 | 0.72403 | 3 | 0 | 3 |
| IGSF21 | SLC16A11 | 0.7163 | 3 | 0 | 3 |
| IGSF21 | AGAP2 | 0.711757 | 3 | 0 | 3 |
| IGSF21 | POU4F3 | 0.708994 | 3 | 0 | 3 |
| IGSF21 | OPRD1 | 0.708304 | 4 | 0 | 4 |
| IGSF21 | ACTL6B | 0.707623 | 4 | 0 | 4 |
| IGSF21 | FTHL17 | 0.705746 | 3 | 0 | 3 |
| IGSF21 | ANKFN1 | 0.704454 | 3 | 0 | 3 |
| IGSF21 | RIN1 | 0.699981 | 3 | 0 | 3 |
| IGSF21 | ZNF777 | 0.698419 | 3 | 0 | 3 |
| IGSF21 | SEMA3B | 0.698415 | 3 | 0 | 3 |
For details and further investigation, click here
