| Full name: glutamate ionotropic receptor NMDA type subunit 2C | Alias Symbol: GluN2C | ||
| Type: protein-coding gene | Cytoband: 17q25.1 | ||
| Entrez ID: 2905 | HGNC ID: HGNC:4587 | Ensembl Gene: ENSG00000161509 | OMIM ID: 138254 |
| Drug and gene relationship at DGIdb | |||
GRIN2C involved pathways:
Expression of GRIN2C:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | GRIN2C | 2905 | 217573_at | 0.1382 | 0.5136 | |
| GSE20347 | GRIN2C | 2905 | 217573_at | -0.0011 | 0.9931 | |
| GSE23400 | GRIN2C | 2905 | 210400_at | -0.2274 | 0.0000 | |
| GSE26886 | GRIN2C | 2905 | 1569268_at | -0.0269 | 0.8486 | |
| GSE29001 | GRIN2C | 2905 | 210400_at | -0.1372 | 0.4132 | |
| GSE38129 | GRIN2C | 2905 | 217573_at | -0.0015 | 0.9857 | |
| GSE45670 | GRIN2C | 2905 | 217573_at | 0.0455 | 0.6058 | |
| GSE53622 | GRIN2C | 2905 | 63953 | -0.3512 | 0.0000 | |
| GSE53624 | GRIN2C | 2905 | 63953 | -0.4921 | 0.0000 | |
| GSE63941 | GRIN2C | 2905 | 217573_at | -0.2374 | 0.0471 | |
| GSE77861 | GRIN2C | 2905 | 1569268_at | -0.0773 | 0.3444 | |
| GSE97050 | GRIN2C | 2905 | A_23_P49546 | -0.4116 | 0.1189 | |
| SRP133303 | GRIN2C | 2905 | RNAseq | 0.1166 | 0.5566 | |
| SRP159526 | GRIN2C | 2905 | RNAseq | 1.4720 | 0.0371 | |
| SRP219564 | GRIN2C | 2905 | RNAseq | 0.6409 | 0.3320 | |
| TCGA | GRIN2C | 2905 | RNAseq | -0.5313 | 0.0205 |
Upregulated datasets: 1; Downregulated datasets: 0.
Survival by GRIN2C expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of GRIN2C:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | GRIN2C | 2905 | 6 | 2 | 22 | |
| GSE20123 | GRIN2C | 2905 | 6 | 2 | 22 | |
| GSE43470 | GRIN2C | 2905 | 5 | 3 | 35 | |
| GSE46452 | GRIN2C | 2905 | 33 | 0 | 26 | |
| GSE47630 | GRIN2C | 2905 | 8 | 1 | 31 | |
| GSE54993 | GRIN2C | 2905 | 2 | 5 | 63 | |
| GSE54994 | GRIN2C | 2905 | 10 | 4 | 39 | |
| GSE60625 | GRIN2C | 2905 | 6 | 0 | 5 | |
| GSE74703 | GRIN2C | 2905 | 5 | 1 | 30 | |
| GSE74704 | GRIN2C | 2905 | 4 | 1 | 15 | |
| TCGA | GRIN2C | 2905 | 32 | 10 | 54 |
Total number of gains: 117; Total number of losses: 29; Total Number of normals: 342.
Somatic mutations of GRIN2C:
Generating mutation plots.
Highly correlated genes for GRIN2C:
Showing top 20/717 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| GRIN2C | TMEM179 | 0.761314 | 3 | 0 | 3 |
| GRIN2C | SLC24A4 | 0.752921 | 3 | 0 | 3 |
| GRIN2C | NR1I3 | 0.718172 | 4 | 0 | 4 |
| GRIN2C | VGF | 0.711139 | 4 | 0 | 4 |
| GRIN2C | ASB10 | 0.70728 | 3 | 0 | 3 |
| GRIN2C | ENGASE | 0.706014 | 3 | 0 | 3 |
| GRIN2C | CHRD | 0.698637 | 4 | 0 | 4 |
| GRIN2C | SPRN | 0.698475 | 3 | 0 | 3 |
| GRIN2C | ABCA4 | 0.698311 | 4 | 0 | 4 |
| GRIN2C | OVGP1 | 0.690424 | 5 | 0 | 5 |
| GRIN2C | TMEM235 | 0.689601 | 3 | 0 | 3 |
| GRIN2C | C19orf25 | 0.686591 | 3 | 0 | 3 |
| GRIN2C | ALX3 | 0.684901 | 4 | 0 | 4 |
| GRIN2C | ARMC5 | 0.68305 | 3 | 0 | 3 |
| GRIN2C | GP9 | 0.676293 | 6 | 0 | 5 |
| GRIN2C | ODF1 | 0.6751 | 4 | 0 | 4 |
| GRIN2C | IGHMBP2 | 0.673549 | 3 | 0 | 3 |
| GRIN2C | KRT35 | 0.672704 | 4 | 0 | 3 |
| GRIN2C | GRID2 | 0.672504 | 4 | 0 | 3 |
| GRIN2C | FSCN3 | 0.671495 | 5 | 0 | 5 |
For details and further investigation, click here
