| Full name: cAMP regulated phosphoprotein 21 | Alias Symbol: ARPP-21|TARPP|R3HDM3 | ||
| Type: protein-coding gene | Cytoband: 3p22.3 | ||
| Entrez ID: 10777 | HGNC ID: HGNC:16968 | Ensembl Gene: ENSG00000172995 | OMIM ID: 605488 |
| Drug and gene relationship at DGIdb | |||
Expression of ARPP21:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | ARPP21 | 10777 | 231935_at | -0.0638 | 0.8294 | |
| GSE20347 | ARPP21 | 10777 | 220359_s_at | 0.0336 | 0.6069 | |
| GSE23400 | ARPP21 | 10777 | 220359_s_at | -0.0428 | 0.1677 | |
| GSE26886 | ARPP21 | 10777 | 231935_at | -0.1372 | 0.0709 | |
| GSE29001 | ARPP21 | 10777 | 220359_s_at | -0.1396 | 0.3761 | |
| GSE38129 | ARPP21 | 10777 | 220359_s_at | -0.0600 | 0.2729 | |
| GSE45670 | ARPP21 | 10777 | 231935_at | -0.0029 | 0.9819 | |
| GSE53622 | ARPP21 | 10777 | 12132 | -0.2714 | 0.0525 | |
| GSE53624 | ARPP21 | 10777 | 32788 | 0.0748 | 0.5588 | |
| GSE63941 | ARPP21 | 10777 | 231935_at | -0.2066 | 0.2651 | |
| GSE77861 | ARPP21 | 10777 | 231935_at | -0.0661 | 0.5449 | |
| TCGA | ARPP21 | 10777 | RNAseq | -3.7857 | 0.0246 |
Upregulated datasets: 0; Downregulated datasets: 1.
Survival by ARPP21 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of ARPP21:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | ARPP21 | 10777 | 0 | 18 | 12 | |
| GSE20123 | ARPP21 | 10777 | 0 | 18 | 12 | |
| GSE43470 | ARPP21 | 10777 | 0 | 21 | 22 | |
| GSE46452 | ARPP21 | 10777 | 2 | 17 | 40 | |
| GSE47630 | ARPP21 | 10777 | 1 | 25 | 14 | |
| GSE54993 | ARPP21 | 10777 | 6 | 3 | 61 | |
| GSE54994 | ARPP21 | 10777 | 1 | 32 | 20 | |
| GSE60625 | ARPP21 | 10777 | 5 | 0 | 6 | |
| GSE74703 | ARPP21 | 10777 | 0 | 18 | 18 | |
| GSE74704 | ARPP21 | 10777 | 0 | 12 | 8 | |
| TCGA | ARPP21 | 10777 | 0 | 71 | 25 |
Total number of gains: 15; Total number of losses: 235; Total Number of normals: 238.
Somatic mutations of ARPP21:
Generating mutation plots.
Highly correlated genes for ARPP21:
Showing top 20/715 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| ARPP21 | CER1 | 0.725794 | 4 | 0 | 4 |
| ARPP21 | PRODH2 | 0.719633 | 4 | 0 | 4 |
| ARPP21 | SYNGR1 | 0.706904 | 3 | 0 | 3 |
| ARPP21 | SYT13 | 0.703418 | 4 | 0 | 4 |
| ARPP21 | ART4 | 0.703211 | 4 | 0 | 4 |
| ARPP21 | MTTP | 0.699472 | 3 | 0 | 3 |
| ARPP21 | CDC25C | 0.697177 | 3 | 0 | 3 |
| ARPP21 | RAB3IL1 | 0.693964 | 4 | 0 | 4 |
| ARPP21 | OR10H3 | 0.693363 | 5 | 0 | 5 |
| ARPP21 | SLC17A4 | 0.691975 | 5 | 0 | 5 |
| ARPP21 | GML | 0.69136 | 4 | 0 | 4 |
| ARPP21 | LIPF | 0.68813 | 3 | 0 | 3 |
| ARPP21 | C1orf105 | 0.685842 | 4 | 0 | 4 |
| ARPP21 | MMP26 | 0.68421 | 5 | 0 | 5 |
| ARPP21 | KIR2DS5 | 0.682281 | 4 | 0 | 4 |
| ARPP21 | GPD1 | 0.682196 | 3 | 0 | 3 |
| ARPP21 | SULT2A1 | 0.678171 | 3 | 0 | 3 |
| ARPP21 | ATP4B | 0.677189 | 3 | 0 | 3 |
| ARPP21 | ALX3 | 0.675754 | 3 | 0 | 3 |
| ARPP21 | LUZP4 | 0.672123 | 4 | 0 | 4 |
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