| Full name: leucine rich repeat containing 2 | Alias Symbol: | ||
| Type: protein-coding gene | Cytoband: 3p21.31 | ||
| Entrez ID: 79442 | HGNC ID: HGNC:14676 | Ensembl Gene: ENSG00000163827 | OMIM ID: 607180 |
| Drug and gene relationship at DGIdb | |||
Expression of LRRC2:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | LRRC2 | 79442 | 219949_at | -0.4324 | 0.0480 | |
| GSE20347 | LRRC2 | 79442 | 219949_at | -0.1062 | 0.0241 | |
| GSE23400 | LRRC2 | 79442 | 219949_at | -0.0552 | 0.0016 | |
| GSE26886 | LRRC2 | 79442 | 219949_at | 0.0495 | 0.4360 | |
| GSE29001 | LRRC2 | 79442 | 219949_at | 0.0053 | 0.9725 | |
| GSE38129 | LRRC2 | 79442 | 219949_at | -0.3195 | 0.0007 | |
| GSE45670 | LRRC2 | 79442 | 231781_s_at | -0.2932 | 0.0001 | |
| GSE53622 | LRRC2 | 79442 | 8488 | 0.0829 | 0.4878 | |
| GSE53624 | LRRC2 | 79442 | 8488 | 0.3897 | 0.0004 | |
| GSE63941 | LRRC2 | 79442 | 219949_at | -2.7918 | 0.0037 | |
| GSE77861 | LRRC2 | 79442 | 231781_s_at | -0.0569 | 0.5041 | |
| GSE97050 | LRRC2 | 79442 | A_23_P155463 | -0.1653 | 0.5319 | |
| SRP064894 | LRRC2 | 79442 | RNAseq | -0.4026 | 0.1810 | |
| SRP133303 | LRRC2 | 79442 | RNAseq | -0.4035 | 0.0012 | |
| SRP159526 | LRRC2 | 79442 | RNAseq | -0.5073 | 0.2063 | |
| SRP193095 | LRRC2 | 79442 | RNAseq | -0.0512 | 0.7729 | |
| SRP219564 | LRRC2 | 79442 | RNAseq | -0.2264 | 0.6551 | |
| TCGA | LRRC2 | 79442 | RNAseq | -2.8600 | 0.0000 |
Upregulated datasets: 0; Downregulated datasets: 2.
Survival by LRRC2 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of LRRC2:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | LRRC2 | 79442 | 0 | 17 | 13 | |
| GSE20123 | LRRC2 | 79442 | 0 | 18 | 12 | |
| GSE43470 | LRRC2 | 79442 | 0 | 20 | 23 | |
| GSE46452 | LRRC2 | 79442 | 2 | 17 | 40 | |
| GSE47630 | LRRC2 | 79442 | 2 | 23 | 15 | |
| GSE54993 | LRRC2 | 79442 | 7 | 2 | 61 | |
| GSE54994 | LRRC2 | 79442 | 0 | 36 | 17 | |
| GSE60625 | LRRC2 | 79442 | 5 | 0 | 6 | |
| GSE74703 | LRRC2 | 79442 | 0 | 15 | 21 | |
| GSE74704 | LRRC2 | 79442 | 0 | 12 | 8 | |
| TCGA | LRRC2 | 79442 | 1 | 75 | 20 |
Total number of gains: 17; Total number of losses: 235; Total Number of normals: 236.
Somatic mutations of LRRC2:
Generating mutation plots.
Highly correlated genes for LRRC2:
Showing top 20/184 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| LRRC2 | C16orf89 | 0.767819 | 4 | 0 | 4 |
| LRRC2 | MYOCD | 0.727527 | 3 | 0 | 3 |
| LRRC2 | MASP2 | 0.721129 | 3 | 0 | 3 |
| LRRC2 | SH2D1B | 0.720454 | 3 | 0 | 3 |
| LRRC2 | SCARA5 | 0.708781 | 3 | 0 | 3 |
| LRRC2 | CCL23 | 0.701123 | 4 | 0 | 4 |
| LRRC2 | RCAN2 | 0.685175 | 5 | 0 | 4 |
| LRRC2 | MAGEE2 | 0.684658 | 4 | 0 | 3 |
| LRRC2 | NEXN | 0.683842 | 3 | 0 | 3 |
| LRRC2 | ALX3 | 0.679633 | 3 | 0 | 3 |
| LRRC2 | ABCB1 | 0.678448 | 7 | 0 | 5 |
| LRRC2 | ADORA1 | 0.669499 | 3 | 0 | 3 |
| LRRC2 | SETDB2 | 0.66513 | 4 | 0 | 3 |
| LRRC2 | GREM2 | 0.664767 | 6 | 0 | 5 |
| LRRC2 | NPR2 | 0.663911 | 4 | 0 | 3 |
| LRRC2 | AK5 | 0.662491 | 5 | 0 | 5 |
| LRRC2 | PTGDS | 0.660232 | 6 | 0 | 5 |
| LRRC2 | ADIPOQ | 0.656193 | 5 | 0 | 5 |
| LRRC2 | RSPO3 | 0.65586 | 3 | 0 | 3 |
| LRRC2 | DPT | 0.655783 | 5 | 0 | 4 |
For details and further investigation, click here
