| Full name: ankyrin repeat domain 46 | Alias Symbol: | ||
| Type: protein-coding gene | Cytoband: 8q22.3 | ||
| Entrez ID: 157567 | HGNC ID: HGNC:27229 | Ensembl Gene: ENSG00000186106 | OMIM ID: |
| Drug and gene relationship at DGIdb | |||
Expression of ANKRD46:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | ANKRD46 | 157567 | 212731_at | 0.4453 | 0.4221 | |
| GSE20347 | ANKRD46 | 157567 | 212731_at | 0.2842 | 0.1863 | |
| GSE23400 | ANKRD46 | 157567 | 212731_at | 0.3871 | 0.0014 | |
| GSE26886 | ANKRD46 | 157567 | 212731_at | -0.8302 | 0.0290 | |
| GSE29001 | ANKRD46 | 157567 | 212731_at | 0.1064 | 0.7379 | |
| GSE38129 | ANKRD46 | 157567 | 212731_at | -0.0033 | 0.9863 | |
| GSE45670 | ANKRD46 | 157567 | 212731_at | 0.0953 | 0.4700 | |
| GSE53622 | ANKRD46 | 157567 | 19569 | -0.2159 | 0.0155 | |
| GSE53624 | ANKRD46 | 157567 | 19569 | -0.2275 | 0.0018 | |
| GSE63941 | ANKRD46 | 157567 | 212731_at | -0.2162 | 0.6686 | |
| GSE77861 | ANKRD46 | 157567 | 212731_at | 0.1473 | 0.6843 | |
| GSE97050 | ANKRD46 | 157567 | A_23_P94095 | -0.3695 | 0.2727 | |
| SRP007169 | ANKRD46 | 157567 | RNAseq | -0.7133 | 0.1076 | |
| SRP008496 | ANKRD46 | 157567 | RNAseq | -0.3911 | 0.1172 | |
| SRP064894 | ANKRD46 | 157567 | RNAseq | 0.0032 | 0.9878 | |
| SRP133303 | ANKRD46 | 157567 | RNAseq | -0.2941 | 0.0269 | |
| SRP159526 | ANKRD46 | 157567 | RNAseq | 0.1890 | 0.3911 | |
| SRP193095 | ANKRD46 | 157567 | RNAseq | -0.2272 | 0.1037 | |
| SRP219564 | ANKRD46 | 157567 | RNAseq | -0.0809 | 0.8703 | |
| TCGA | ANKRD46 | 157567 | RNAseq | -0.0910 | 0.1609 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by ANKRD46 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of ANKRD46:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | ANKRD46 | 157567 | 17 | 0 | 13 | |
| GSE20123 | ANKRD46 | 157567 | 17 | 0 | 13 | |
| GSE43470 | ANKRD46 | 157567 | 22 | 0 | 21 | |
| GSE46452 | ANKRD46 | 157567 | 24 | 0 | 35 | |
| GSE47630 | ANKRD46 | 157567 | 24 | 0 | 16 | |
| GSE54993 | ANKRD46 | 157567 | 0 | 20 | 50 | |
| GSE54994 | ANKRD46 | 157567 | 38 | 1 | 14 | |
| GSE60625 | ANKRD46 | 157567 | 0 | 4 | 7 | |
| GSE74703 | ANKRD46 | 157567 | 19 | 0 | 17 | |
| GSE74704 | ANKRD46 | 157567 | 12 | 0 | 8 | |
| TCGA | ANKRD46 | 157567 | 59 | 1 | 36 |
Total number of gains: 232; Total number of losses: 26; Total Number of normals: 230.
Somatic mutations of ANKRD46:
Generating mutation plots.
Highly correlated genes for ANKRD46:
Showing top 20/264 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| ANKRD46 | USP21 | 0.768866 | 3 | 0 | 3 |
| ANKRD46 | GRB14 | 0.768695 | 3 | 0 | 3 |
| ANKRD46 | CTDSPL | 0.747289 | 3 | 0 | 3 |
| ANKRD46 | ZNF573 | 0.742885 | 3 | 0 | 3 |
| ANKRD46 | CARS2 | 0.742789 | 3 | 0 | 3 |
| ANKRD46 | METTL8 | 0.739954 | 4 | 0 | 3 |
| ANKRD46 | SLC25A16 | 0.737483 | 3 | 0 | 3 |
| ANKRD46 | UTP23 | 0.729137 | 3 | 0 | 3 |
| ANKRD46 | GGPS1 | 0.72116 | 4 | 0 | 4 |
| ANKRD46 | SAP30L | 0.720928 | 3 | 0 | 3 |
| ANKRD46 | NAPEPLD | 0.715887 | 3 | 0 | 3 |
| ANKRD46 | DYNC1I2 | 0.711098 | 3 | 0 | 3 |
| ANKRD46 | MYLIP | 0.71034 | 3 | 0 | 3 |
| ANKRD46 | MRFAP1L1 | 0.708389 | 4 | 0 | 3 |
| ANKRD46 | TMEM181 | 0.707706 | 4 | 0 | 4 |
| ANKRD46 | ZFYVE26 | 0.707136 | 3 | 0 | 3 |
| ANKRD46 | PPARA | 0.701606 | 3 | 0 | 3 |
| ANKRD46 | RIMKLB | 0.696951 | 3 | 0 | 3 |
| ANKRD46 | TPP2 | 0.696383 | 3 | 0 | 3 |
| ANKRD46 | RLIM | 0.696366 | 3 | 0 | 3 |
For details and further investigation, click here
