| Full name: growth factor receptor bound protein 14 | Alias Symbol: | ||
| Type: protein-coding gene | Cytoband: 2q24.3 | ||
| Entrez ID: 2888 | HGNC ID: HGNC:4565 | Ensembl Gene: ENSG00000115290 | OMIM ID: 601524 |
| Drug and gene relationship at DGIdb | |||
Expression of GRB14:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | GRB14 | 2888 | 206204_at | 0.5784 | 0.6396 | |
| GSE20347 | GRB14 | 2888 | 206204_at | 0.0253 | 0.9004 | |
| GSE23400 | GRB14 | 2888 | 206204_at | 0.0055 | 0.8753 | |
| GSE26886 | GRB14 | 2888 | 206204_at | 0.8153 | 0.0272 | |
| GSE29001 | GRB14 | 2888 | 206204_at | 0.3397 | 0.4584 | |
| GSE38129 | GRB14 | 2888 | 206204_at | -0.1111 | 0.6421 | |
| GSE45670 | GRB14 | 2888 | 206204_at | -1.0412 | 0.0033 | |
| GSE53622 | GRB14 | 2888 | 83179 | -0.8469 | 0.0000 | |
| GSE53624 | GRB14 | 2888 | 83179 | -0.5296 | 0.0015 | |
| GSE63941 | GRB14 | 2888 | 206204_at | -1.0733 | 0.4230 | |
| GSE77861 | GRB14 | 2888 | 206204_at | -0.2568 | 0.3260 | |
| GSE97050 | GRB14 | 2888 | A_23_P154526 | -0.3712 | 0.3384 | |
| SRP064894 | GRB14 | 2888 | RNAseq | -0.4687 | 0.1555 | |
| SRP133303 | GRB14 | 2888 | RNAseq | 0.4429 | 0.4430 | |
| SRP159526 | GRB14 | 2888 | RNAseq | -0.6019 | 0.3479 | |
| SRP219564 | GRB14 | 2888 | RNAseq | -0.8430 | 0.2995 | |
| TCGA | GRB14 | 2888 | RNAseq | 0.0397 | 0.9297 |
Upregulated datasets: 0; Downregulated datasets: 1.
Survival by GRB14 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of GRB14:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | GRB14 | 2888 | 6 | 1 | 23 | |
| GSE20123 | GRB14 | 2888 | 6 | 1 | 23 | |
| GSE43470 | GRB14 | 2888 | 7 | 1 | 35 | |
| GSE46452 | GRB14 | 2888 | 1 | 4 | 54 | |
| GSE47630 | GRB14 | 2888 | 5 | 3 | 32 | |
| GSE54993 | GRB14 | 2888 | 0 | 5 | 65 | |
| GSE54994 | GRB14 | 2888 | 11 | 2 | 40 | |
| GSE60625 | GRB14 | 2888 | 0 | 3 | 8 | |
| GSE74703 | GRB14 | 2888 | 5 | 1 | 30 | |
| GSE74704 | GRB14 | 2888 | 3 | 0 | 17 | |
| TCGA | GRB14 | 2888 | 24 | 9 | 63 |
Total number of gains: 68; Total number of losses: 30; Total Number of normals: 390.
Somatic mutations of GRB14:
Generating mutation plots.
Highly correlated genes for GRB14:
Showing top 20/168 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| GRB14 | ANKRD46 | 0.768695 | 3 | 0 | 3 |
| GRB14 | ZNF623 | 0.756892 | 3 | 0 | 3 |
| GRB14 | FRY | 0.726566 | 3 | 0 | 3 |
| GRB14 | ARMC1 | 0.720903 | 3 | 0 | 3 |
| GRB14 | TMEM98 | 0.71052 | 3 | 0 | 3 |
| GRB14 | RB1CC1 | 0.699275 | 3 | 0 | 3 |
| GRB14 | ADI1 | 0.686475 | 3 | 0 | 3 |
| GRB14 | SFMBT1 | 0.684371 | 3 | 0 | 3 |
| GRB14 | PPP1R16A | 0.684202 | 3 | 0 | 3 |
| GRB14 | GFRA1 | 0.681626 | 3 | 0 | 3 |
| GRB14 | PTCD2 | 0.676195 | 3 | 0 | 3 |
| GRB14 | CSPP1 | 0.67564 | 3 | 0 | 3 |
| GRB14 | FXYD6 | 0.669866 | 3 | 0 | 3 |
| GRB14 | MTPAP | 0.669488 | 3 | 0 | 3 |
| GRB14 | REV1 | 0.668413 | 3 | 0 | 3 |
| GRB14 | ANKRD23 | 0.667103 | 3 | 0 | 3 |
| GRB14 | PIGG | 0.666722 | 3 | 0 | 3 |
| GRB14 | RBM41 | 0.665892 | 4 | 0 | 3 |
| GRB14 | EIF5A2 | 0.662989 | 3 | 0 | 3 |
| GRB14 | NFYB | 0.661204 | 3 | 0 | 3 |
For details and further investigation, click here
