| Full name: dynein cytoplasmic 1 intermediate chain 2 | Alias Symbol: DIC74 | ||
| Type: protein-coding gene | Cytoband: 2q31.1 | ||
| Entrez ID: 1781 | HGNC ID: HGNC:2964 | Ensembl Gene: ENSG00000077380 | OMIM ID: 603331 |
| Drug and gene relationship at DGIdb | |||
Expression of DYNC1I2:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | DYNC1I2 | 1781 | 211684_s_at | 0.0043 | 0.9948 | |
| GSE20347 | DYNC1I2 | 1781 | 211684_s_at | -0.3338 | 0.0397 | |
| GSE23400 | DYNC1I2 | 1781 | 211684_s_at | -0.0558 | 0.5014 | |
| GSE26886 | DYNC1I2 | 1781 | 211684_s_at | -0.2711 | 0.1472 | |
| GSE29001 | DYNC1I2 | 1781 | 211684_s_at | -0.2712 | 0.3725 | |
| GSE38129 | DYNC1I2 | 1781 | 211684_s_at | -0.1639 | 0.1831 | |
| GSE45670 | DYNC1I2 | 1781 | 211684_s_at | -0.1253 | 0.2308 | |
| GSE53622 | DYNC1I2 | 1781 | 14197 | -0.2476 | 0.0002 | |
| GSE53624 | DYNC1I2 | 1781 | 14197 | -0.2896 | 0.0000 | |
| GSE63941 | DYNC1I2 | 1781 | 211684_s_at | -0.8196 | 0.0063 | |
| GSE77861 | DYNC1I2 | 1781 | 211684_s_at | -0.3385 | 0.1376 | |
| GSE97050 | DYNC1I2 | 1781 | A_23_P154108 | -0.2729 | 0.1993 | |
| SRP007169 | DYNC1I2 | 1781 | RNAseq | -0.8460 | 0.0075 | |
| SRP008496 | DYNC1I2 | 1781 | RNAseq | -0.6739 | 0.0000 | |
| SRP064894 | DYNC1I2 | 1781 | RNAseq | -0.1868 | 0.0989 | |
| SRP133303 | DYNC1I2 | 1781 | RNAseq | -0.0931 | 0.4309 | |
| SRP159526 | DYNC1I2 | 1781 | RNAseq | -0.5710 | 0.0048 | |
| SRP193095 | DYNC1I2 | 1781 | RNAseq | -0.4702 | 0.0001 | |
| SRP219564 | DYNC1I2 | 1781 | RNAseq | -0.2470 | 0.3451 | |
| TCGA | DYNC1I2 | 1781 | RNAseq | 0.0225 | 0.6429 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by DYNC1I2 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of DYNC1I2:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | DYNC1I2 | 1781 | 8 | 0 | 22 | |
| GSE20123 | DYNC1I2 | 1781 | 8 | 0 | 22 | |
| GSE43470 | DYNC1I2 | 1781 | 6 | 1 | 36 | |
| GSE46452 | DYNC1I2 | 1781 | 1 | 4 | 54 | |
| GSE47630 | DYNC1I2 | 1781 | 5 | 3 | 32 | |
| GSE54993 | DYNC1I2 | 1781 | 0 | 5 | 65 | |
| GSE54994 | DYNC1I2 | 1781 | 11 | 3 | 39 | |
| GSE60625 | DYNC1I2 | 1781 | 0 | 3 | 8 | |
| GSE74703 | DYNC1I2 | 1781 | 5 | 1 | 30 | |
| GSE74704 | DYNC1I2 | 1781 | 5 | 0 | 15 | |
| TCGA | DYNC1I2 | 1781 | 27 | 6 | 63 |
Total number of gains: 76; Total number of losses: 26; Total Number of normals: 386.
Somatic mutations of DYNC1I2:
Generating mutation plots.
Highly correlated genes for DYNC1I2:
Showing top 20/518 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| DYNC1I2 | PDZD11 | 0.808645 | 3 | 0 | 3 |
| DYNC1I2 | C6orf62 | 0.778782 | 3 | 0 | 3 |
| DYNC1I2 | APOB | 0.76811 | 3 | 0 | 3 |
| DYNC1I2 | ZNF585A | 0.763591 | 3 | 0 | 3 |
| DYNC1I2 | CWC22 | 0.760846 | 4 | 0 | 3 |
| DYNC1I2 | ANKHD1 | 0.748121 | 3 | 0 | 3 |
| DYNC1I2 | XKR6 | 0.743461 | 3 | 0 | 3 |
| DYNC1I2 | PRADC1 | 0.734411 | 3 | 0 | 3 |
| DYNC1I2 | SUSD1 | 0.72996 | 3 | 0 | 3 |
| DYNC1I2 | TRNT1 | 0.727852 | 3 | 0 | 3 |
| DYNC1I2 | TUBGCP3 | 0.727608 | 3 | 0 | 3 |
| DYNC1I2 | MSRA | 0.718008 | 3 | 0 | 3 |
| DYNC1I2 | NAALAD2 | 0.716069 | 3 | 0 | 3 |
| DYNC1I2 | FBXL17 | 0.71449 | 4 | 0 | 4 |
| DYNC1I2 | ANKRD46 | 0.711098 | 3 | 0 | 3 |
| DYNC1I2 | KCTD21 | 0.710985 | 4 | 0 | 4 |
| DYNC1I2 | ARL5A | 0.70638 | 3 | 0 | 3 |
| DYNC1I2 | SPAG7 | 0.704727 | 3 | 0 | 3 |
| DYNC1I2 | LTBP2 | 0.703301 | 3 | 0 | 3 |
| DYNC1I2 | RPL27A | 0.703222 | 3 | 0 | 3 |
For details and further investigation, click here
