| Full name: spermatogenesis and oogenesis specific basic helix-loop-helix 1 | Alias Symbol: NOHLH|TEB2|bA100C15.3|bHLHe80|SPATA27 | ||
| Type: protein-coding gene | Cytoband: 9q34.3 | ||
| Entrez ID: 402381 | HGNC ID: HGNC:27845 | Ensembl Gene: ENSG00000165643 | OMIM ID: 610224 |
| Drug and gene relationship at DGIdb | |||
Expression of SOHLH1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | SOHLH1 | 402381 | 1561403_at | 0.3122 | 0.4473 | |
| GSE26886 | SOHLH1 | 402381 | 1561403_at | 0.3075 | 0.2843 | |
| GSE45670 | SOHLH1 | 402381 | 1561403_at | 0.0769 | 0.7084 | |
| GSE53622 | SOHLH1 | 402381 | 127415 | 0.4624 | 0.0109 | |
| GSE53624 | SOHLH1 | 402381 | 127415 | 1.1725 | 0.0000 | |
| GSE63941 | SOHLH1 | 402381 | 1561403_at | 0.1773 | 0.5273 | |
| GSE77861 | SOHLH1 | 402381 | 1561403_at | 0.0931 | 0.7664 | |
| GSE97050 | SOHLH1 | 402381 | A_24_P307964 | 0.2015 | 0.3791 | |
| TCGA | SOHLH1 | 402381 | RNAseq | 4.7166 | 0.0012 |
Upregulated datasets: 2; Downregulated datasets: 0.
Survival by SOHLH1 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of SOHLH1:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | SOHLH1 | 402381 | 4 | 7 | 19 | |
| GSE20123 | SOHLH1 | 402381 | 4 | 7 | 19 | |
| GSE43470 | SOHLH1 | 402381 | 3 | 7 | 33 | |
| GSE46452 | SOHLH1 | 402381 | 6 | 13 | 40 | |
| GSE47630 | SOHLH1 | 402381 | 6 | 15 | 19 | |
| GSE54993 | SOHLH1 | 402381 | 3 | 3 | 64 | |
| GSE54994 | SOHLH1 | 402381 | 12 | 8 | 33 | |
| GSE60625 | SOHLH1 | 402381 | 0 | 0 | 11 | |
| GSE74703 | SOHLH1 | 402381 | 3 | 5 | 28 | |
| GSE74704 | SOHLH1 | 402381 | 2 | 5 | 13 | |
| TCGA | SOHLH1 | 402381 | 28 | 25 | 43 |
Total number of gains: 71; Total number of losses: 95; Total Number of normals: 322.
Somatic mutations of SOHLH1:
Generating mutation plots.
Highly correlated genes for SOHLH1:
Showing top 20/61 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| SOHLH1 | CEL | 0.835834 | 3 | 0 | 3 |
| SOHLH1 | ORM1 | 0.792344 | 4 | 0 | 4 |
| SOHLH1 | FBLN7 | 0.78543 | 3 | 0 | 3 |
| SOHLH1 | IL22RA2 | 0.784148 | 3 | 0 | 3 |
| SOHLH1 | FGFR4 | 0.776944 | 3 | 0 | 3 |
| SOHLH1 | PNMA6A | 0.771323 | 3 | 0 | 3 |
| SOHLH1 | PARP10 | 0.733377 | 3 | 0 | 3 |
| SOHLH1 | GPT | 0.723102 | 3 | 0 | 3 |
| SOHLH1 | RNF44 | 0.720623 | 3 | 0 | 3 |
| SOHLH1 | CDH4 | 0.71639 | 3 | 0 | 3 |
| SOHLH1 | SIL1 | 0.711518 | 3 | 0 | 3 |
| SOHLH1 | CDC34 | 0.708865 | 3 | 0 | 3 |
| SOHLH1 | GPR150 | 0.704263 | 3 | 0 | 3 |
| SOHLH1 | CLCNKB | 0.68402 | 3 | 0 | 3 |
| SOHLH1 | JMJD1C-AS1 | 0.672941 | 3 | 0 | 3 |
| SOHLH1 | C4BPB | 0.671392 | 3 | 0 | 3 |
| SOHLH1 | PPP1R14D | 0.662986 | 3 | 0 | 3 |
| SOHLH1 | FABP7 | 0.662632 | 3 | 0 | 3 |
| SOHLH1 | GDF15 | 0.662507 | 3 | 0 | 3 |
| SOHLH1 | FABP6 | 0.658094 | 4 | 0 | 3 |
For details and further investigation, click here
