| Full name: neuronal pentraxin 1 | Alias Symbol: | ||
| Type: protein-coding gene | Cytoband: 17q25.3 | ||
| Entrez ID: 4884 | HGNC ID: HGNC:7952 | Ensembl Gene: ENSG00000171246 | OMIM ID: 602367 |
| Drug and gene relationship at DGIdb | |||
Expression of NPTX1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | NPTX1 | 4884 | 204684_at | -0.5604 | 0.5908 | |
| GSE20347 | NPTX1 | 4884 | 204684_at | 0.0504 | 0.4751 | |
| GSE23400 | NPTX1 | 4884 | 204684_at | -0.0355 | 0.6568 | |
| GSE26886 | NPTX1 | 4884 | 204684_at | 0.5590 | 0.0499 | |
| GSE29001 | NPTX1 | 4884 | 204684_at | 0.1723 | 0.3702 | |
| GSE38129 | NPTX1 | 4884 | 204684_at | -0.2518 | 0.4254 | |
| GSE45670 | NPTX1 | 4884 | 204684_at | -0.2108 | 0.0594 | |
| GSE63941 | NPTX1 | 4884 | 204684_at | -1.6811 | 0.1093 | |
| GSE77861 | NPTX1 | 4884 | 204684_at | 0.0388 | 0.7637 | |
| GSE97050 | NPTX1 | 4884 | A_23_P124905 | -1.8470 | 0.1299 | |
| SRP064894 | NPTX1 | 4884 | RNAseq | 0.4599 | 0.1728 | |
| SRP133303 | NPTX1 | 4884 | RNAseq | -0.7894 | 0.0543 | |
| SRP159526 | NPTX1 | 4884 | RNAseq | -0.4017 | 0.5264 | |
| TCGA | NPTX1 | 4884 | RNAseq | -0.6271 | 0.0956 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by NPTX1 expression:
 |
| TCGA |
Note: Click image to view full size file.
Copy number change of NPTX1:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | NPTX1 | 4884 | 4 | 3 | 23 | |
| GSE20123 | NPTX1 | 4884 | 4 | 3 | 23 | |
| GSE43470 | NPTX1 | 4884 | 3 | 5 | 35 | |
| GSE46452 | NPTX1 | 4884 | 34 | 0 | 25 | |
| GSE47630 | NPTX1 | 4884 | 9 | 2 | 29 | |
| GSE54993 | NPTX1 | 4884 | 2 | 5 | 63 | |
| GSE54994 | NPTX1 | 4884 | 10 | 6 | 37 | |
| GSE60625 | NPTX1 | 4884 | 6 | 0 | 5 | |
| GSE74703 | NPTX1 | 4884 | 3 | 3 | 30 | |
| GSE74704 | NPTX1 | 4884 | 4 | 3 | 13 | |
| TCGA | NPTX1 | 4884 | 28 | 10 | 58 |
Total number of gains: 107; Total number of losses: 40; Total Number of normals: 341.
Somatic mutations of NPTX1:
Generating mutation plots.
Highly correlated genes for NPTX1:
Showing top 20/426 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| NPTX1 | RBM24 | 0.76268 | 4 | 0 | 4 |
| NPTX1 | ZMAT4 | 0.74436 | 5 | 0 | 5 |
| NPTX1 | SORCS1 | 0.742062 | 3 | 0 | 3 |
| NPTX1 | ZNF540 | 0.739181 | 3 | 0 | 3 |
| NPTX1 | RIC3 | 0.736851 | 3 | 0 | 3 |
| NPTX1 | RXRG | 0.732066 | 4 | 0 | 4 |
| NPTX1 | APOF | 0.729726 | 3 | 0 | 3 |
| NPTX1 | CKMT2 | 0.729279 | 4 | 0 | 3 |
| NPTX1 | LMO3 | 0.72428 | 4 | 0 | 3 |
| NPTX1 | SOX17 | 0.722644 | 3 | 0 | 3 |
| NPTX1 | ALPK3 | 0.721293 | 4 | 0 | 4 |
| NPTX1 | BVES | 0.720099 | 4 | 0 | 4 |
| NPTX1 | SH3GL2 | 0.717991 | 5 | 0 | 4 |
| NPTX1 | SFRP5 | 0.712059 | 3 | 0 | 3 |
| NPTX1 | PLIN4 | 0.711021 | 3 | 0 | 3 |
| NPTX1 | ALDH1A2 | 0.707456 | 4 | 0 | 3 |
| NPTX1 | ADAMTS19 | 0.701253 | 3 | 0 | 3 |
| NPTX1 | C16orf86 | 0.70097 | 3 | 0 | 3 |
| NPTX1 | LIX1L | 0.70046 | 3 | 0 | 3 |
| NPTX1 | ARHGEF10 | 0.696753 | 3 | 0 | 3 |
For details and further investigation, click here
