| Full name: 3-oxoacid CoA-transferase 2 | Alias Symbol: FKSG25|FLJ00030|SCOT-T | ||
| Type: protein-coding gene | Cytoband: 1p34.2 | ||
| Entrez ID: 64064 | HGNC ID: HGNC:18606 | Ensembl Gene: ENSG00000198754 | OMIM ID: 610289 |
| Drug and gene relationship at DGIdb | |||
Expression of OXCT2:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | OXCT2 | 64064 | 220256_s_at | -0.1454 | 0.5436 | |
| GSE20347 | OXCT2 | 64064 | 220256_s_at | -0.0096 | 0.9212 | |
| GSE23400 | OXCT2 | 64064 | 220256_s_at | -0.0559 | 0.1358 | |
| GSE26886 | OXCT2 | 64064 | 220256_s_at | 0.3761 | 0.0057 | |
| GSE29001 | OXCT2 | 64064 | 220256_s_at | -0.0168 | 0.9103 | |
| GSE38129 | OXCT2 | 64064 | 220256_s_at | -0.0900 | 0.3697 | |
| GSE45670 | OXCT2 | 64064 | 220256_s_at | 0.0510 | 0.6310 | |
| GSE53622 | OXCT2 | 64064 | 10120 | 0.1174 | 0.3689 | |
| GSE53624 | OXCT2 | 64064 | 10120 | 0.3053 | 0.0281 | |
| GSE63941 | OXCT2 | 64064 | 220256_s_at | -0.1972 | 0.2367 | |
| GSE77861 | OXCT2 | 64064 | 220256_s_at | 0.0641 | 0.6749 | |
| GSE97050 | OXCT2 | 64064 | A_23_P137896 | 0.0371 | 0.9095 | |
| SRP159526 | OXCT2 | 64064 | RNAseq | 1.8280 | 0.0105 | |
| SRP219564 | OXCT2 | 64064 | RNAseq | 0.5641 | 0.4158 | |
| TCGA | OXCT2 | 64064 | RNAseq | 1.0245 | 0.0175 |
Upregulated datasets: 2; Downregulated datasets: 0.
Survival by OXCT2 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of OXCT2:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | OXCT2 | 64064 | 3 | 4 | 23 | |
| GSE20123 | OXCT2 | 64064 | 2 | 3 | 25 | |
| GSE43470 | OXCT2 | 64064 | 8 | 2 | 33 | |
| GSE46452 | OXCT2 | 64064 | 4 | 1 | 54 | |
| GSE47630 | OXCT2 | 64064 | 9 | 2 | 29 | |
| GSE54993 | OXCT2 | 64064 | 0 | 1 | 69 | |
| GSE54994 | OXCT2 | 64064 | 13 | 2 | 38 | |
| GSE60625 | OXCT2 | 64064 | 0 | 0 | 11 | |
| GSE74703 | OXCT2 | 64064 | 7 | 1 | 28 | |
| GSE74704 | OXCT2 | 64064 | 1 | 0 | 19 | |
| TCGA | OXCT2 | 64064 | 16 | 16 | 64 |
Total number of gains: 63; Total number of losses: 32; Total Number of normals: 393.
Somatic mutations of OXCT2:
Generating mutation plots.
Highly correlated genes for OXCT2:
Showing top 20/434 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| OXCT2 | MRPL55 | 0.724172 | 3 | 0 | 3 |
| OXCT2 | SARDH | 0.721051 | 6 | 0 | 6 |
| OXCT2 | C11orf68 | 0.714479 | 3 | 0 | 3 |
| OXCT2 | NRG1 | 0.704242 | 3 | 0 | 3 |
| OXCT2 | LBP | 0.691035 | 3 | 0 | 3 |
| OXCT2 | MNT | 0.690035 | 3 | 0 | 3 |
| OXCT2 | TRAF2 | 0.683642 | 3 | 0 | 3 |
| OXCT2 | ELAVL3 | 0.681347 | 5 | 0 | 5 |
| OXCT2 | LINC00598 | 0.676464 | 3 | 0 | 3 |
| OXCT2 | LIPF | 0.676133 | 4 | 0 | 4 |
| OXCT2 | XYLT2 | 0.672991 | 3 | 0 | 3 |
| OXCT2 | NCDN | 0.670067 | 4 | 0 | 3 |
| OXCT2 | C1orf35 | 0.66369 | 3 | 0 | 3 |
| OXCT2 | TTC9B | 0.663462 | 3 | 0 | 3 |
| OXCT2 | C19orf47 | 0.662801 | 4 | 0 | 4 |
| OXCT2 | GUCY2F | 0.658526 | 3 | 0 | 3 |
| OXCT2 | PTPRU | 0.654463 | 4 | 0 | 3 |
| OXCT2 | NPFF | 0.650628 | 3 | 0 | 3 |
| OXCT2 | CYTH3 | 0.646925 | 3 | 0 | 3 |
| OXCT2 | MYPOP | 0.645687 | 3 | 0 | 3 |
For details and further investigation, click here
