| Full name: ring finger protein 5 | Alias Symbol: NG2|G16|RING5|RMA1 | ||
| Type: protein-coding gene | Cytoband: 6p21.32 | ||
| Entrez ID: 6048 | HGNC ID: HGNC:10068 | Ensembl Gene: ENSG00000204308 | OMIM ID: 602677 |
| Drug and gene relationship at DGIdb | |||
Expression of RNF5:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | RNF5 | 6048 | 216018_at | 0.1730 | 0.5926 | |
| GSE20347 | RNF5 | 6048 | 216018_at | 0.0231 | 0.7860 | |
| GSE23400 | RNF5 | 6048 | 216018_at | -0.1366 | 0.0007 | |
| GSE26886 | RNF5 | 6048 | 216018_at | -0.0268 | 0.8773 | |
| GSE29001 | RNF5 | 6048 | 216018_at | -0.0999 | 0.6067 | |
| GSE38129 | RNF5 | 6048 | 216018_at | -0.0709 | 0.3880 | |
| GSE45670 | RNF5 | 6048 | 216018_at | 0.0777 | 0.4445 | |
| GSE53622 | RNF5 | 6048 | 2351 | -0.1335 | 0.0544 | |
| GSE53624 | RNF5 | 6048 | 2351 | 0.1621 | 0.0023 | |
| GSE63941 | RNF5 | 6048 | 216018_at | -0.1399 | 0.2976 | |
| GSE77861 | RNF5 | 6048 | 216018_at | -0.1179 | 0.3310 | |
| GSE97050 | RNF5 | 6048 | A_23_P8095 | -0.0900 | 0.7791 | |
| SRP007169 | RNF5 | 6048 | RNAseq | -0.6316 | 0.0773 | |
| SRP008496 | RNF5 | 6048 | RNAseq | -0.7963 | 0.0009 | |
| SRP064894 | RNF5 | 6048 | RNAseq | 0.1932 | 0.5073 | |
| SRP133303 | RNF5 | 6048 | RNAseq | -0.1911 | 0.1513 | |
| SRP159526 | RNF5 | 6048 | RNAseq | -0.0353 | 0.8401 | |
| SRP193095 | RNF5 | 6048 | RNAseq | -0.3155 | 0.0125 | |
| SRP219564 | RNF5 | 6048 | RNAseq | -0.1677 | 0.6044 | |
| TCGA | RNF5 | 6048 | RNAseq | -0.1382 | 0.0070 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by RNF5 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of RNF5:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | RNF5 | 6048 | 5 | 1 | 24 | |
| GSE20123 | RNF5 | 6048 | 5 | 1 | 24 | |
| GSE43470 | RNF5 | 6048 | 5 | 1 | 37 | |
| GSE46452 | RNF5 | 6048 | 1 | 10 | 48 | |
| GSE47630 | RNF5 | 6048 | 7 | 4 | 29 | |
| GSE54993 | RNF5 | 6048 | 2 | 1 | 67 | |
| GSE54994 | RNF5 | 6048 | 11 | 4 | 38 | |
| GSE60625 | RNF5 | 6048 | 0 | 1 | 10 | |
| GSE74703 | RNF5 | 6048 | 5 | 0 | 31 | |
| GSE74704 | RNF5 | 6048 | 2 | 0 | 18 | |
| TCGA | RNF5 | 6048 | 16 | 16 | 64 |
Total number of gains: 59; Total number of losses: 39; Total Number of normals: 390.
Somatic mutations of RNF5:
Generating mutation plots.
Highly correlated genes for RNF5:
Showing top 20/566 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| RNF5 | EDDM3A | 0.719042 | 3 | 0 | 3 |
| RNF5 | FASLG | 0.70533 | 4 | 0 | 4 |
| RNF5 | PSG9 | 0.701784 | 5 | 0 | 5 |
| RNF5 | BTN1A1 | 0.699816 | 4 | 0 | 4 |
| RNF5 | IL1RAPL2 | 0.690851 | 4 | 0 | 4 |
| RNF5 | NTNG1 | 0.687727 | 4 | 0 | 3 |
| RNF5 | IFNA21 | 0.680007 | 4 | 0 | 4 |
| RNF5 | MEFV | 0.670159 | 3 | 0 | 3 |
| RNF5 | DEFA4 | 0.664833 | 6 | 0 | 5 |
| RNF5 | ASCL3 | 0.664329 | 6 | 0 | 5 |
| RNF5 | IFNA4 | 0.663449 | 5 | 0 | 5 |
| RNF5 | NXPE4 | 0.65806 | 4 | 0 | 4 |
| RNF5 | REG3A | 0.655601 | 4 | 0 | 4 |
| RNF5 | DMC1 | 0.651757 | 3 | 0 | 3 |
| RNF5 | CRHBP | 0.651635 | 5 | 0 | 5 |
| RNF5 | GABRA2 | 0.649283 | 3 | 0 | 3 |
| RNF5 | KRT76 | 0.648232 | 5 | 0 | 5 |
| RNF5 | APOF | 0.648108 | 3 | 0 | 3 |
| RNF5 | UBASH3A | 0.647718 | 3 | 0 | 3 |
| RNF5 | HUNK | 0.644648 | 3 | 0 | 3 |
For details and further investigation, click here
