| Full name: tumor protein p53 inducible protein 11 | Alias Symbol: PIG11 | ||
| Type: protein-coding gene | Cytoband: 11p11.2 | ||
| Entrez ID: 9537 | HGNC ID: HGNC:16842 | Ensembl Gene: ENSG00000175274 | OMIM ID: 617867 |
| Drug and gene relationship at DGIdb | |||
Expression of TP53I11:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | TP53I11 | 9537 | 203421_at | 0.3774 | 0.2400 | |
| GSE20347 | TP53I11 | 9537 | 203421_at | 0.0505 | 0.7141 | |
| GSE23400 | TP53I11 | 9537 | 203421_at | -0.0151 | 0.7636 | |
| GSE26886 | TP53I11 | 9537 | 203421_at | 0.5503 | 0.0044 | |
| GSE29001 | TP53I11 | 9537 | 216919_at | -0.2264 | 0.2504 | |
| GSE38129 | TP53I11 | 9537 | 203421_at | 0.0467 | 0.6645 | |
| GSE45670 | TP53I11 | 9537 | 203421_at | -0.1615 | 0.1669 | |
| GSE53622 | TP53I11 | 9537 | 99136 | 0.0949 | 0.4423 | |
| GSE53624 | TP53I11 | 9537 | 99136 | 0.0373 | 0.7763 | |
| GSE63941 | TP53I11 | 9537 | 203421_at | -0.9660 | 0.0184 | |
| GSE77861 | TP53I11 | 9537 | 203421_at | 0.0723 | 0.7142 | |
| GSE97050 | TP53I11 | 9537 | A_24_P160969 | 0.0840 | 0.7675 | |
| SRP007169 | TP53I11 | 9537 | RNAseq | -0.9805 | 0.1440 | |
| SRP008496 | TP53I11 | 9537 | RNAseq | -0.4440 | 0.2474 | |
| SRP064894 | TP53I11 | 9537 | RNAseq | 0.4031 | 0.1417 | |
| SRP133303 | TP53I11 | 9537 | RNAseq | 0.5871 | 0.0115 | |
| SRP159526 | TP53I11 | 9537 | RNAseq | -0.2767 | 0.4202 | |
| SRP193095 | TP53I11 | 9537 | RNAseq | 0.1855 | 0.5031 | |
| SRP219564 | TP53I11 | 9537 | RNAseq | 0.2799 | 0.4974 | |
| TCGA | TP53I11 | 9537 | RNAseq | -0.0819 | 0.3420 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by TP53I11 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of TP53I11:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | TP53I11 | 9537 | 1 | 8 | 21 | |
| GSE20123 | TP53I11 | 9537 | 1 | 7 | 22 | |
| GSE43470 | TP53I11 | 9537 | 2 | 4 | 37 | |
| GSE46452 | TP53I11 | 9537 | 8 | 5 | 46 | |
| GSE47630 | TP53I11 | 9537 | 3 | 9 | 28 | |
| GSE54993 | TP53I11 | 9537 | 3 | 0 | 67 | |
| GSE54994 | TP53I11 | 9537 | 4 | 9 | 40 | |
| GSE60625 | TP53I11 | 9537 | 0 | 0 | 11 | |
| GSE74703 | TP53I11 | 9537 | 2 | 2 | 32 | |
| GSE74704 | TP53I11 | 9537 | 1 | 6 | 13 | |
| TCGA | TP53I11 | 9537 | 15 | 20 | 61 |
Total number of gains: 40; Total number of losses: 70; Total Number of normals: 378.
Somatic mutations of TP53I11:
Generating mutation plots.
Highly correlated genes for TP53I11:
Showing top 20/534 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| TP53I11 | TSHR | 0.839505 | 3 | 0 | 3 |
| TP53I11 | ZNF467 | 0.804536 | 3 | 0 | 3 |
| TP53I11 | GRIN2D | 0.80451 | 4 | 0 | 4 |
| TP53I11 | KCNC4 | 0.786352 | 4 | 0 | 4 |
| TP53I11 | MED24 | 0.786067 | 3 | 0 | 3 |
| TP53I11 | CAMKK2 | 0.779636 | 3 | 0 | 3 |
| TP53I11 | CCDC14 | 0.76902 | 3 | 0 | 3 |
| TP53I11 | MAN1B1 | 0.764129 | 3 | 0 | 3 |
| TP53I11 | MIER2 | 0.76313 | 5 | 0 | 5 |
| TP53I11 | DAPK3 | 0.756496 | 3 | 0 | 3 |
| TP53I11 | ELF4 | 0.754806 | 3 | 0 | 3 |
| TP53I11 | C19orf18 | 0.754311 | 3 | 0 | 3 |
| TP53I11 | TBC1D25 | 0.752793 | 3 | 0 | 3 |
| TP53I11 | USP36 | 0.750483 | 3 | 0 | 3 |
| TP53I11 | TP53I13 | 0.749976 | 3 | 0 | 3 |
| TP53I11 | GOSR2 | 0.749487 | 3 | 0 | 3 |
| TP53I11 | STAT2 | 0.748777 | 5 | 0 | 5 |
| TP53I11 | PPP1R1B | 0.744275 | 3 | 0 | 3 |
| TP53I11 | MTAP | 0.744111 | 3 | 0 | 3 |
| TP53I11 | TAF10 | 0.744104 | 3 | 0 | 3 |
For details and further investigation, click here
