| Full name: arrestin domain containing 4 | Alias Symbol: FLJ36045 | ||
| Type: protein-coding gene | Cytoband: 15q26.2 | ||
| Entrez ID: 91947 | HGNC ID: HGNC:28087 | Ensembl Gene: ENSG00000140450 | OMIM ID: |
| Drug and gene relationship at DGIdb | |||
Expression of ARRDC4:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | ARRDC4 | 91947 | 225283_at | -0.1361 | 0.8950 | |
| GSE26886 | ARRDC4 | 91947 | 225283_at | 0.8240 | 0.0985 | |
| GSE45670 | ARRDC4 | 91947 | 225283_at | 0.0439 | 0.9300 | |
| GSE53622 | ARRDC4 | 91947 | 55713 | 0.1425 | 0.3832 | |
| GSE53624 | ARRDC4 | 91947 | 55713 | 0.3003 | 0.0112 | |
| GSE63941 | ARRDC4 | 91947 | 225283_at | -1.8538 | 0.0888 | |
| GSE77861 | ARRDC4 | 91947 | 225283_at | 0.1083 | 0.8896 | |
| GSE97050 | ARRDC4 | 91947 | A_23_P339818 | -0.6554 | 0.1313 | |
| SRP007169 | ARRDC4 | 91947 | RNAseq | -0.3585 | 0.4530 | |
| SRP008496 | ARRDC4 | 91947 | RNAseq | 0.6861 | 0.0500 | |
| SRP064894 | ARRDC4 | 91947 | RNAseq | 0.1985 | 0.4592 | |
| SRP133303 | ARRDC4 | 91947 | RNAseq | 1.0628 | 0.0003 | |
| SRP159526 | ARRDC4 | 91947 | RNAseq | 1.0560 | 0.0000 | |
| SRP193095 | ARRDC4 | 91947 | RNAseq | 0.2407 | 0.2434 | |
| SRP219564 | ARRDC4 | 91947 | RNAseq | -0.5206 | 0.3555 | |
| TCGA | ARRDC4 | 91947 | RNAseq | -0.4570 | 0.0008 |
Upregulated datasets: 2; Downregulated datasets: 0.
Survival by ARRDC4 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of ARRDC4:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | ARRDC4 | 91947 | 6 | 1 | 23 | |
| GSE20123 | ARRDC4 | 91947 | 6 | 1 | 23 | |
| GSE43470 | ARRDC4 | 91947 | 5 | 5 | 33 | |
| GSE46452 | ARRDC4 | 91947 | 3 | 7 | 49 | |
| GSE47630 | ARRDC4 | 91947 | 9 | 10 | 21 | |
| GSE54993 | ARRDC4 | 91947 | 4 | 6 | 60 | |
| GSE54994 | ARRDC4 | 91947 | 9 | 7 | 37 | |
| GSE60625 | ARRDC4 | 91947 | 4 | 0 | 7 | |
| GSE74703 | ARRDC4 | 91947 | 4 | 4 | 28 | |
| GSE74704 | ARRDC4 | 91947 | 3 | 2 | 15 | |
| TCGA | ARRDC4 | 91947 | 19 | 14 | 63 |
Total number of gains: 72; Total number of losses: 57; Total Number of normals: 359.
Somatic mutations of ARRDC4:
Generating mutation plots.
Highly correlated genes for ARRDC4:
Showing top 20/249 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| ARRDC4 | NGRN | 0.809482 | 3 | 0 | 3 |
| ARRDC4 | MTMR9 | 0.788769 | 3 | 0 | 3 |
| ARRDC4 | KIF5B | 0.740976 | 3 | 0 | 3 |
| ARRDC4 | HMCN1 | 0.737678 | 3 | 0 | 3 |
| ARRDC4 | CCDC88A | 0.732651 | 3 | 0 | 3 |
| ARRDC4 | MAPK10 | 0.727544 | 3 | 0 | 3 |
| ARRDC4 | CYP2U1 | 0.726769 | 3 | 0 | 3 |
| ARRDC4 | CNTLN | 0.725602 | 3 | 0 | 3 |
| ARRDC4 | F8 | 0.720583 | 3 | 0 | 3 |
| ARRDC4 | SORCS1 | 0.719356 | 3 | 0 | 3 |
| ARRDC4 | TWISTNB | 0.706551 | 3 | 0 | 3 |
| ARRDC4 | KLHL15 | 0.705075 | 3 | 0 | 3 |
| ARRDC4 | TMTC1 | 0.701975 | 3 | 0 | 3 |
| ARRDC4 | RNF13 | 0.697863 | 3 | 0 | 3 |
| ARRDC4 | LRRN4CL | 0.696636 | 3 | 0 | 3 |
| ARRDC4 | ZNF490 | 0.696331 | 3 | 0 | 3 |
| ARRDC4 | LIX1L | 0.695094 | 4 | 0 | 4 |
| ARRDC4 | MYADM | 0.694149 | 3 | 0 | 3 |
| ARRDC4 | NSA2 | 0.693423 | 3 | 0 | 3 |
| ARRDC4 | DAG1 | 0.691626 | 3 | 0 | 3 |
For details and further investigation, click here
