| Full name: centlein | Alias Symbol: FLJ20276|bA340N12.1|OTTHUMG00000019597 | ||
| Type: protein-coding gene | Cytoband: 9p22.2 | ||
| Entrez ID: 54875 | HGNC ID: HGNC:23432 | Ensembl Gene: ENSG00000044459 | OMIM ID: 611870 |
| Drug and gene relationship at DGIdb | |||
Expression of CNTLN:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | CNTLN | 54875 | 220095_at | -0.1117 | 0.8819 | |
| GSE20347 | CNTLN | 54875 | 220095_at | -0.0434 | 0.6844 | |
| GSE23400 | CNTLN | 54875 | 220095_at | -0.0171 | 0.6778 | |
| GSE26886 | CNTLN | 54875 | 239989_at | 0.1109 | 0.6122 | |
| GSE29001 | CNTLN | 54875 | 220095_at | 0.2515 | 0.3961 | |
| GSE38129 | CNTLN | 54875 | 220095_at | -0.1159 | 0.4075 | |
| GSE45670 | CNTLN | 54875 | 1559005_s_at | -0.2407 | 0.5840 | |
| GSE53622 | CNTLN | 54875 | 15115 | -0.0377 | 0.7818 | |
| GSE53624 | CNTLN | 54875 | 133649 | 0.5463 | 0.0000 | |
| GSE63941 | CNTLN | 54875 | 241696_at | -0.1547 | 0.8441 | |
| GSE77861 | CNTLN | 54875 | 220095_at | -0.0424 | 0.8094 | |
| GSE97050 | CNTLN | 54875 | A_23_P157963 | -0.1270 | 0.6672 | |
| SRP007169 | CNTLN | 54875 | RNAseq | 3.0594 | 0.0000 | |
| SRP008496 | CNTLN | 54875 | RNAseq | 2.3174 | 0.0000 | |
| SRP064894 | CNTLN | 54875 | RNAseq | 0.7338 | 0.0001 | |
| SRP133303 | CNTLN | 54875 | RNAseq | 0.5613 | 0.0010 | |
| SRP159526 | CNTLN | 54875 | RNAseq | 0.6385 | 0.0809 | |
| SRP193095 | CNTLN | 54875 | RNAseq | 0.4677 | 0.0001 | |
| SRP219564 | CNTLN | 54875 | RNAseq | 0.3491 | 0.3696 | |
| TCGA | CNTLN | 54875 | RNAseq | 0.1678 | 0.2078 |
Upregulated datasets: 2; Downregulated datasets: 0.
Survival by CNTLN expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of CNTLN:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | CNTLN | 54875 | 2 | 16 | 12 | |
| GSE20123 | CNTLN | 54875 | 2 | 16 | 12 | |
| GSE43470 | CNTLN | 54875 | 4 | 11 | 28 | |
| GSE46452 | CNTLN | 54875 | 2 | 23 | 34 | |
| GSE47630 | CNTLN | 54875 | 3 | 27 | 10 | |
| GSE54993 | CNTLN | 54875 | 6 | 2 | 62 | |
| GSE54994 | CNTLN | 54875 | 10 | 16 | 27 | |
| GSE60625 | CNTLN | 54875 | 0 | 0 | 11 | |
| GSE74703 | CNTLN | 54875 | 4 | 8 | 24 | |
| GSE74704 | CNTLN | 54875 | 0 | 13 | 7 | |
| TCGA | CNTLN | 54875 | 14 | 50 | 32 |
Total number of gains: 47; Total number of losses: 182; Total Number of normals: 259.
Somatic mutations of CNTLN:
Generating mutation plots.
Highly correlated genes for CNTLN:
Showing top 20/448 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| CNTLN | ZCCHC24 | 0.773232 | 4 | 0 | 4 |
| CNTLN | EGFLAM | 0.765931 | 3 | 0 | 3 |
| CNTLN | DIAPH2 | 0.763178 | 3 | 0 | 3 |
| CNTLN | PPP3CB | 0.762597 | 3 | 0 | 3 |
| CNTLN | MYOM2 | 0.758001 | 3 | 0 | 3 |
| CNTLN | S1PR3 | 0.750287 | 3 | 0 | 3 |
| CNTLN | SGCA | 0.742629 | 3 | 0 | 3 |
| CNTLN | PEG3 | 0.742395 | 3 | 0 | 3 |
| CNTLN | RASL12 | 0.742173 | 3 | 0 | 3 |
| CNTLN | DOK6 | 0.740786 | 3 | 0 | 3 |
| CNTLN | KANK2 | 0.735707 | 3 | 0 | 3 |
| CNTLN | EPHA3 | 0.734718 | 3 | 0 | 3 |
| CNTLN | TGM2 | 0.733866 | 3 | 0 | 3 |
| CNTLN | RABAC1 | 0.731947 | 3 | 0 | 3 |
| CNTLN | PDK2 | 0.729451 | 3 | 0 | 3 |
| CNTLN | MRGPRF | 0.726222 | 3 | 0 | 3 |
| CNTLN | ARRDC4 | 0.725602 | 3 | 0 | 3 |
| CNTLN | MAPRE2 | 0.725575 | 4 | 0 | 3 |
| CNTLN | AXL | 0.725175 | 4 | 0 | 4 |
| CNTLN | ANGPTL2 | 0.724833 | 3 | 0 | 3 |
For details and further investigation, click here
