| Full name: coiled-coil domain containing 88A | Alias Symbol: FLJ10392|APE|GIV|HkRP1|GRDN | ||
| Type: protein-coding gene | Cytoband: 2p16.1 | ||
| Entrez ID: 55704 | HGNC ID: HGNC:25523 | Ensembl Gene: ENSG00000115355 | OMIM ID: 609736 |
| Drug and gene relationship at DGIdb | |||
Expression of CCDC88A:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | CCDC88A | 55704 | 225045_at | 0.4796 | 0.5862 | |
| GSE20347 | CCDC88A | 55704 | 221078_s_at | 0.2155 | 0.0051 | |
| GSE23400 | CCDC88A | 55704 | 221078_s_at | 0.2165 | 0.0000 | |
| GSE26886 | CCDC88A | 55704 | 225045_at | 0.5487 | 0.0561 | |
| GSE29001 | CCDC88A | 55704 | 221078_s_at | 0.2257 | 0.1037 | |
| GSE38129 | CCDC88A | 55704 | 219387_at | 0.3096 | 0.5712 | |
| GSE45670 | CCDC88A | 55704 | 225045_at | -0.0575 | 0.8984 | |
| GSE53622 | CCDC88A | 55704 | 22449 | 0.7595 | 0.0000 | |
| GSE53624 | CCDC88A | 55704 | 22449 | 0.9736 | 0.0000 | |
| GSE63941 | CCDC88A | 55704 | 225045_at | -1.9863 | 0.0304 | |
| GSE77861 | CCDC88A | 55704 | 238759_at | 0.1177 | 0.4803 | |
| GSE97050 | CCDC88A | 55704 | A_24_P20120 | 0.0726 | 0.8072 | |
| SRP007169 | CCDC88A | 55704 | RNAseq | 3.0962 | 0.0000 | |
| SRP008496 | CCDC88A | 55704 | RNAseq | 2.8958 | 0.0000 | |
| SRP064894 | CCDC88A | 55704 | RNAseq | 1.3095 | 0.0000 | |
| SRP133303 | CCDC88A | 55704 | RNAseq | 0.6345 | 0.0001 | |
| SRP159526 | CCDC88A | 55704 | RNAseq | 1.0124 | 0.0082 | |
| SRP193095 | CCDC88A | 55704 | RNAseq | 1.1076 | 0.0000 | |
| SRP219564 | CCDC88A | 55704 | RNAseq | 0.6311 | 0.1829 | |
| TCGA | CCDC88A | 55704 | RNAseq | 0.0750 | 0.3222 |
Upregulated datasets: 5; Downregulated datasets: 1.
Survival by CCDC88A expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of CCDC88A:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | CCDC88A | 55704 | 10 | 0 | 20 | |
| GSE20123 | CCDC88A | 55704 | 9 | 0 | 21 | |
| GSE43470 | CCDC88A | 55704 | 5 | 0 | 38 | |
| GSE46452 | CCDC88A | 55704 | 2 | 3 | 54 | |
| GSE47630 | CCDC88A | 55704 | 8 | 0 | 32 | |
| GSE54993 | CCDC88A | 55704 | 0 | 5 | 65 | |
| GSE54994 | CCDC88A | 55704 | 12 | 0 | 41 | |
| GSE60625 | CCDC88A | 55704 | 0 | 3 | 8 | |
| GSE74703 | CCDC88A | 55704 | 5 | 0 | 31 | |
| GSE74704 | CCDC88A | 55704 | 9 | 0 | 11 | |
| TCGA | CCDC88A | 55704 | 34 | 3 | 59 |
Total number of gains: 94; Total number of losses: 14; Total Number of normals: 380.
Somatic mutations of CCDC88A:
Generating mutation plots.
Highly correlated genes for CCDC88A:
Showing top 20/1142 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| CCDC88A | RAB34 | 0.804198 | 3 | 0 | 3 |
| CCDC88A | FADS1 | 0.776026 | 3 | 0 | 3 |
| CCDC88A | VASP | 0.773895 | 3 | 0 | 3 |
| CCDC88A | FGF7 | 0.773891 | 3 | 0 | 3 |
| CCDC88A | ZNF225 | 0.763924 | 3 | 0 | 3 |
| CCDC88A | FCGR3A | 0.755752 | 3 | 0 | 3 |
| CCDC88A | LRRC8C | 0.747816 | 3 | 0 | 3 |
| CCDC88A | TIMP4 | 0.739391 | 3 | 0 | 3 |
| CCDC88A | DHRSX | 0.735412 | 3 | 0 | 3 |
| CCDC88A | ARRDC4 | 0.732651 | 3 | 0 | 3 |
| CCDC88A | CEP170 | 0.730469 | 3 | 0 | 3 |
| CCDC88A | FAM126A | 0.72866 | 3 | 0 | 3 |
| CCDC88A | PARM1 | 0.725509 | 3 | 0 | 3 |
| CCDC88A | TCF21 | 0.720863 | 3 | 0 | 3 |
| CCDC88A | ZFP1 | 0.72084 | 4 | 0 | 4 |
| CCDC88A | C5orf24 | 0.71958 | 3 | 0 | 3 |
| CCDC88A | LETM2 | 0.714619 | 3 | 0 | 3 |
| CCDC88A | GNAI2 | 0.712803 | 4 | 0 | 3 |
| CCDC88A | C17orf67 | 0.705057 | 3 | 0 | 3 |
| CCDC88A | FGL2 | 0.702222 | 3 | 0 | 3 |
For details and further investigation, click here
