| Full name: dystroglycan 1 | Alias Symbol: A3a|156DAG|AGRNR|DAG | ||
| Type: protein-coding gene | Cytoband: 3p21.31 | ||
| Entrez ID: 1605 | HGNC ID: HGNC:2666 | Ensembl Gene: ENSG00000173402 | OMIM ID: 128239 |
| Drug and gene relationship at DGIdb | |||
Expression of DAG1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | DAG1 | 1605 | 205417_s_at | 0.1372 | 0.7199 | |
| GSE20347 | DAG1 | 1605 | 205417_s_at | -0.0943 | 0.4077 | |
| GSE23400 | DAG1 | 1605 | 205417_s_at | -0.0125 | 0.8682 | |
| GSE26886 | DAG1 | 1605 | 205417_s_at | 0.4915 | 0.0151 | |
| GSE29001 | DAG1 | 1605 | 205417_s_at | 0.0254 | 0.9018 | |
| GSE38129 | DAG1 | 1605 | 205417_s_at | -0.1809 | 0.1569 | |
| GSE45670 | DAG1 | 1605 | 205417_s_at | -0.0267 | 0.8785 | |
| GSE53622 | DAG1 | 1605 | 57284 | -0.1895 | 0.0046 | |
| GSE53624 | DAG1 | 1605 | 57284 | -0.2027 | 0.0008 | |
| GSE63941 | DAG1 | 1605 | 205417_s_at | -0.1748 | 0.7696 | |
| GSE77861 | DAG1 | 1605 | 205417_s_at | 0.2533 | 0.0679 | |
| GSE97050 | DAG1 | 1605 | A_24_P225961 | -0.3932 | 0.3221 | |
| SRP007169 | DAG1 | 1605 | RNAseq | -0.1439 | 0.7151 | |
| SRP008496 | DAG1 | 1605 | RNAseq | 0.0076 | 0.9731 | |
| SRP064894 | DAG1 | 1605 | RNAseq | 0.0255 | 0.8487 | |
| SRP133303 | DAG1 | 1605 | RNAseq | 0.0293 | 0.8567 | |
| SRP159526 | DAG1 | 1605 | RNAseq | 0.3571 | 0.2485 | |
| SRP193095 | DAG1 | 1605 | RNAseq | 0.1172 | 0.4460 | |
| SRP219564 | DAG1 | 1605 | RNAseq | -0.3307 | 0.5094 | |
| TCGA | DAG1 | 1605 | RNAseq | -0.1804 | 0.0000 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by DAG1 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of DAG1:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | DAG1 | 1605 | 0 | 18 | 12 | |
| GSE20123 | DAG1 | 1605 | 0 | 19 | 11 | |
| GSE43470 | DAG1 | 1605 | 0 | 18 | 25 | |
| GSE46452 | DAG1 | 1605 | 2 | 16 | 41 | |
| GSE47630 | DAG1 | 1605 | 1 | 24 | 15 | |
| GSE54993 | DAG1 | 1605 | 6 | 2 | 62 | |
| GSE54994 | DAG1 | 1605 | 0 | 36 | 17 | |
| GSE60625 | DAG1 | 1605 | 5 | 0 | 6 | |
| GSE74703 | DAG1 | 1605 | 0 | 14 | 22 | |
| GSE74704 | DAG1 | 1605 | 0 | 12 | 8 | |
| TCGA | DAG1 | 1605 | 0 | 78 | 18 |
Total number of gains: 14; Total number of losses: 237; Total Number of normals: 237.
Somatic mutations of DAG1:
Generating mutation plots.
Highly correlated genes for DAG1:
Showing top 20/735 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| DAG1 | PARVB | 0.769728 | 3 | 0 | 3 |
| DAG1 | RBM33 | 0.764305 | 3 | 0 | 3 |
| DAG1 | NVL | 0.761194 | 3 | 0 | 3 |
| DAG1 | STOML1 | 0.760346 | 3 | 0 | 3 |
| DAG1 | DENND4B | 0.757751 | 3 | 0 | 3 |
| DAG1 | AAAS | 0.747939 | 3 | 0 | 3 |
| DAG1 | DDX20 | 0.746096 | 3 | 0 | 3 |
| DAG1 | ZNF623 | 0.745306 | 3 | 0 | 3 |
| DAG1 | PTK2 | 0.741326 | 3 | 0 | 3 |
| DAG1 | MEPCE | 0.738397 | 4 | 0 | 4 |
| DAG1 | MAPK10 | 0.735955 | 3 | 0 | 3 |
| DAG1 | SOX13 | 0.735272 | 4 | 0 | 3 |
| DAG1 | LSM4 | 0.73255 | 4 | 0 | 4 |
| DAG1 | MRPS26 | 0.731455 | 4 | 0 | 4 |
| DAG1 | SLC41A1 | 0.731129 | 3 | 0 | 3 |
| DAG1 | PPTC7 | 0.730095 | 3 | 0 | 3 |
| DAG1 | MSTO1 | 0.729857 | 3 | 0 | 3 |
| DAG1 | CDC37 | 0.729055 | 3 | 0 | 3 |
| DAG1 | TMED8 | 0.725635 | 3 | 0 | 3 |
| DAG1 | ZNF317 | 0.722238 | 4 | 0 | 3 |
For details and further investigation, click here
