| Full name: activating transcription factor 7 interacting protein | Alias Symbol: FLJ10688|p621 | ||
| Type: protein-coding gene | Cytoband: 12p13.1 | ||
| Entrez ID: 55729 | HGNC ID: HGNC:20092 | Ensembl Gene: ENSG00000171681 | OMIM ID: 613644 |
| Drug and gene relationship at DGIdb | |||
Screen Evidence:
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Expression of ATF7IP:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | ATF7IP | 55729 | 231825_x_at | 0.1958 | 0.7666 | |
| GSE20347 | ATF7IP | 55729 | 218987_at | -0.1233 | 0.4734 | |
| GSE23400 | ATF7IP | 55729 | 218987_at | 0.0583 | 0.4921 | |
| GSE26886 | ATF7IP | 55729 | 225917_at | -0.1865 | 0.4345 | |
| GSE29001 | ATF7IP | 55729 | 218987_at | -0.0582 | 0.8501 | |
| GSE38129 | ATF7IP | 55729 | 218987_at | -0.0749 | 0.6436 | |
| GSE45670 | ATF7IP | 55729 | 231825_x_at | 0.2683 | 0.0184 | |
| GSE53622 | ATF7IP | 55729 | 2331 | 0.0296 | 0.7033 | |
| GSE53624 | ATF7IP | 55729 | 2331 | 0.0985 | 0.1320 | |
| GSE63941 | ATF7IP | 55729 | 231825_x_at | 0.0848 | 0.7217 | |
| GSE77861 | ATF7IP | 55729 | 231825_x_at | 0.6330 | 0.0811 | |
| GSE97050 | ATF7IP | 55729 | A_24_P923757 | 0.2862 | 0.2859 | |
| SRP007169 | ATF7IP | 55729 | RNAseq | -0.1962 | 0.6356 | |
| SRP008496 | ATF7IP | 55729 | RNAseq | -0.0641 | 0.8167 | |
| SRP064894 | ATF7IP | 55729 | RNAseq | -0.4872 | 0.0300 | |
| SRP133303 | ATF7IP | 55729 | RNAseq | 0.1492 | 0.4636 | |
| SRP159526 | ATF7IP | 55729 | RNAseq | -0.0608 | 0.8001 | |
| SRP193095 | ATF7IP | 55729 | RNAseq | -0.0985 | 0.4094 | |
| SRP219564 | ATF7IP | 55729 | RNAseq | -0.5142 | 0.2105 | |
| TCGA | ATF7IP | 55729 | RNAseq | 0.1909 | 0.0002 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by ATF7IP expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of ATF7IP:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | ATF7IP | 55729 | 6 | 2 | 22 | |
| GSE20123 | ATF7IP | 55729 | 6 | 2 | 22 | |
| GSE43470 | ATF7IP | 55729 | 9 | 4 | 30 | |
| GSE46452 | ATF7IP | 55729 | 10 | 1 | 48 | |
| GSE47630 | ATF7IP | 55729 | 14 | 1 | 25 | |
| GSE54993 | ATF7IP | 55729 | 1 | 9 | 60 | |
| GSE54994 | ATF7IP | 55729 | 10 | 2 | 41 | |
| GSE60625 | ATF7IP | 55729 | 0 | 1 | 10 | |
| GSE74703 | ATF7IP | 55729 | 9 | 3 | 24 | |
| GSE74704 | ATF7IP | 55729 | 4 | 1 | 15 | |
| TCGA | ATF7IP | 55729 | 41 | 6 | 49 |
Total number of gains: 110; Total number of losses: 32; Total Number of normals: 346.
Somatic mutations of ATF7IP:
Generating mutation plots.
Highly correlated genes for ATF7IP:
Showing top 20/159 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| ATF7IP | PPIG | 0.841383 | 3 | 0 | 3 |
| ATF7IP | NLN | 0.834426 | 5 | 0 | 5 |
| ATF7IP | CHD7 | 0.818138 | 3 | 0 | 3 |
| ATF7IP | TRMT10B | 0.801995 | 3 | 0 | 3 |
| ATF7IP | SAMD4B | 0.791017 | 3 | 0 | 3 |
| ATF7IP | SSB | 0.769194 | 3 | 0 | 3 |
| ATF7IP | NPHP3 | 0.768849 | 3 | 0 | 3 |
| ATF7IP | OCIAD1 | 0.760809 | 4 | 0 | 4 |
| ATF7IP | NBEAL1 | 0.760339 | 3 | 0 | 3 |
| ATF7IP | NIT2 | 0.746792 | 3 | 0 | 3 |
| ATF7IP | ZBED6 | 0.735737 | 3 | 0 | 3 |
| ATF7IP | SYMPK | 0.734589 | 5 | 0 | 5 |
| ATF7IP | WDR75 | 0.734402 | 3 | 0 | 3 |
| ATF7IP | NAA15 | 0.728082 | 4 | 0 | 4 |
| ATF7IP | RASEF | 0.719543 | 3 | 0 | 3 |
| ATF7IP | MBD3 | 0.716899 | 3 | 0 | 3 |
| ATF7IP | CCAR1 | 0.715327 | 4 | 0 | 4 |
| ATF7IP | VPS13B | 0.713066 | 3 | 0 | 3 |
| ATF7IP | UBE2W | 0.712545 | 3 | 0 | 3 |
| ATF7IP | ZNF33A | 0.711381 | 3 | 0 | 3 |
For details and further investigation, click here
