| Full name: vacuolar protein sorting 13 homolog B | Alias Symbol: | ||
| Type: protein-coding gene | Cytoband: 8q22.2 | ||
| Entrez ID: 157680 | HGNC ID: HGNC:2183 | Ensembl Gene: ENSG00000132549 | OMIM ID: 607817 |
| Drug and gene relationship at DGIdb | |||
Expression of VPS13B:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | VPS13B | 157680 | 213243_at | 0.0963 | 0.8543 | |
| GSE20347 | VPS13B | 157680 | 213243_at | -0.2800 | 0.2255 | |
| GSE23400 | VPS13B | 157680 | 213243_at | 0.1498 | 0.1147 | |
| GSE26886 | VPS13B | 157680 | 213243_at | 0.5703 | 0.0198 | |
| GSE29001 | VPS13B | 157680 | 213243_at | -0.1128 | 0.8126 | |
| GSE38129 | VPS13B | 157680 | 213243_at | -0.2689 | 0.0737 | |
| GSE45670 | VPS13B | 157680 | 213243_at | -0.5018 | 0.0004 | |
| GSE53622 | VPS13B | 157680 | 81327 | 0.4801 | 0.0000 | |
| GSE53624 | VPS13B | 157680 | 82371 | -0.2420 | 0.0014 | |
| GSE63941 | VPS13B | 157680 | 213243_at | -1.2852 | 0.0601 | |
| GSE77861 | VPS13B | 157680 | 236254_at | 0.2886 | 0.1217 | |
| GSE97050 | VPS13B | 157680 | A_23_P82975 | 0.2669 | 0.2332 | |
| SRP007169 | VPS13B | 157680 | RNAseq | 0.5078 | 0.1503 | |
| SRP008496 | VPS13B | 157680 | RNAseq | 0.7523 | 0.0028 | |
| SRP064894 | VPS13B | 157680 | RNAseq | 0.0908 | 0.7520 | |
| SRP133303 | VPS13B | 157680 | RNAseq | 0.0795 | 0.3869 | |
| SRP159526 | VPS13B | 157680 | RNAseq | -0.1583 | 0.5161 | |
| SRP193095 | VPS13B | 157680 | RNAseq | 0.3504 | 0.0024 | |
| SRP219564 | VPS13B | 157680 | RNAseq | -0.0081 | 0.9818 | |
| TCGA | VPS13B | 157680 | RNAseq | -0.0413 | 0.4271 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by VPS13B expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of VPS13B:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | VPS13B | 157680 | 17 | 0 | 13 | |
| GSE20123 | VPS13B | 157680 | 17 | 0 | 13 | |
| GSE43470 | VPS13B | 157680 | 21 | 1 | 21 | |
| GSE46452 | VPS13B | 157680 | 24 | 0 | 35 | |
| GSE47630 | VPS13B | 157680 | 24 | 0 | 16 | |
| GSE54993 | VPS13B | 157680 | 1 | 19 | 50 | |
| GSE54994 | VPS13B | 157680 | 37 | 2 | 14 | |
| GSE60625 | VPS13B | 157680 | 0 | 4 | 7 | |
| GSE74703 | VPS13B | 157680 | 18 | 1 | 17 | |
| GSE74704 | VPS13B | 157680 | 12 | 0 | 8 | |
| TCGA | VPS13B | 157680 | 55 | 5 | 36 |
Total number of gains: 226; Total number of losses: 32; Total Number of normals: 230.
Somatic mutations of VPS13B:
Generating mutation plots.
Highly correlated genes for VPS13B:
Showing top 20/186 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| VPS13B | FAM161A | 0.775666 | 3 | 0 | 3 |
| VPS13B | ZFP90 | 0.771823 | 3 | 0 | 3 |
| VPS13B | METTL15 | 0.753032 | 3 | 0 | 3 |
| VPS13B | SPATS2 | 0.736141 | 3 | 0 | 3 |
| VPS13B | PTPN4 | 0.727825 | 4 | 0 | 4 |
| VPS13B | CWC22 | 0.726902 | 3 | 0 | 3 |
| VPS13B | RUFY2 | 0.722846 | 3 | 0 | 3 |
| VPS13B | ZBED6 | 0.717224 | 4 | 0 | 4 |
| VPS13B | ATF7IP | 0.713066 | 3 | 0 | 3 |
| VPS13B | RAB7B | 0.707063 | 3 | 0 | 3 |
| VPS13B | RBM22 | 0.701419 | 3 | 0 | 3 |
| VPS13B | EXOC8 | 0.700257 | 3 | 0 | 3 |
| VPS13B | GPN1 | 0.690986 | 3 | 0 | 3 |
| VPS13B | SBF2 | 0.688967 | 5 | 0 | 5 |
| VPS13B | C9orf64 | 0.686679 | 4 | 0 | 3 |
| VPS13B | DHRS7 | 0.684046 | 3 | 0 | 3 |
| VPS13B | UTP23 | 0.679542 | 5 | 0 | 4 |
| VPS13B | RICTOR | 0.678373 | 3 | 0 | 3 |
| VPS13B | SLC41A1 | 0.6758 | 3 | 0 | 3 |
| VPS13B | ANAPC10 | 0.669245 | 4 | 0 | 4 |
For details and further investigation, click here
