| Full name: RAS and EF-hand domain containing | Alias Symbol: FLJ31614 | ||
| Type: protein-coding gene | Cytoband: 9q21.32 | ||
| Entrez ID: 158158 | HGNC ID: HGNC:26464 | Ensembl Gene: ENSG00000165105 | OMIM ID: 611344 |
| Drug and gene relationship at DGIdb | |||
Expression of RASEF:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | RASEF | 158158 | 1553185_at | 0.7009 | 0.4975 | |
| GSE26886 | RASEF | 158158 | 1553185_at | 1.4917 | 0.0000 | |
| GSE45670 | RASEF | 158158 | 1553185_at | 0.9982 | 0.0000 | |
| GSE53622 | RASEF | 158158 | 5523 | -1.1578 | 0.0000 | |
| GSE53624 | RASEF | 158158 | 5523 | -1.5132 | 0.0000 | |
| GSE63941 | RASEF | 158158 | 1553185_at | 0.7295 | 0.2218 | |
| GSE77861 | RASEF | 158158 | 1553185_at | 2.2557 | 0.0015 | |
| GSE97050 | RASEF | 158158 | A_24_P183994 | 0.3608 | 0.2620 | |
| SRP007169 | RASEF | 158158 | RNAseq | -0.3885 | 0.5540 | |
| SRP008496 | RASEF | 158158 | RNAseq | -1.0176 | 0.1832 | |
| SRP064894 | RASEF | 158158 | RNAseq | -1.1977 | 0.0045 | |
| SRP133303 | RASEF | 158158 | RNAseq | -0.7116 | 0.1110 | |
| SRP159526 | RASEF | 158158 | RNAseq | -1.6206 | 0.0064 | |
| SRP193095 | RASEF | 158158 | RNAseq | -1.3043 | 0.0003 | |
| SRP219564 | RASEF | 158158 | RNAseq | -0.5077 | 0.5620 | |
| TCGA | RASEF | 158158 | RNAseq | -0.7545 | 0.0105 |
Upregulated datasets: 2; Downregulated datasets: 5.
Survival by RASEF expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of RASEF:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | RASEF | 158158 | 5 | 10 | 15 | |
| GSE20123 | RASEF | 158158 | 5 | 10 | 15 | |
| GSE43470 | RASEF | 158158 | 6 | 5 | 32 | |
| GSE46452 | RASEF | 158158 | 6 | 14 | 39 | |
| GSE47630 | RASEF | 158158 | 1 | 18 | 21 | |
| GSE54993 | RASEF | 158158 | 4 | 2 | 64 | |
| GSE54994 | RASEF | 158158 | 4 | 12 | 37 | |
| GSE60625 | RASEF | 158158 | 0 | 0 | 11 | |
| GSE74703 | RASEF | 158158 | 5 | 4 | 27 | |
| GSE74704 | RASEF | 158158 | 3 | 7 | 10 | |
| TCGA | RASEF | 158158 | 20 | 29 | 47 |
Total number of gains: 59; Total number of losses: 111; Total Number of normals: 318.
Somatic mutations of RASEF:
Generating mutation plots.
Highly correlated genes for RASEF:
Showing top 20/298 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| RASEF | MORC2 | 0.766 | 4 | 0 | 4 |
| RASEF | ACBD6 | 0.756294 | 3 | 0 | 3 |
| RASEF | ATF7IP | 0.719543 | 3 | 0 | 3 |
| RASEF | WAC-AS1 | 0.717753 | 3 | 0 | 3 |
| RASEF | U2SURP | 0.710375 | 4 | 0 | 4 |
| RASEF | PTPN4 | 0.709026 | 4 | 0 | 3 |
| RASEF | NEB | 0.705633 | 5 | 0 | 5 |
| RASEF | ALKBH6 | 0.704339 | 4 | 0 | 3 |
| RASEF | TIGD1 | 0.702282 | 4 | 0 | 4 |
| RASEF | IPO9 | 0.700332 | 5 | 0 | 4 |
| RASEF | ACVR1C | 0.698723 | 4 | 0 | 4 |
| RASEF | HOXC9 | 0.697751 | 4 | 0 | 4 |
| RASEF | TRMT12 | 0.677376 | 3 | 0 | 3 |
| RASEF | POU6F2-AS2 | 0.67682 | 5 | 0 | 4 |
| RASEF | EFS | 0.674484 | 3 | 0 | 3 |
| RASEF | NIFK | 0.674018 | 4 | 0 | 4 |
| RASEF | UBQLN4 | 0.671276 | 4 | 0 | 3 |
| RASEF | APOBEC3B | 0.669098 | 3 | 0 | 3 |
| RASEF | ABCC5 | 0.667299 | 4 | 0 | 4 |
| RASEF | SLFN5 | 0.666567 | 3 | 0 | 3 |
For details and further investigation, click here
