| Full name: ATPase phospholipid transporting 8B2 | Alias Symbol: ATPID|KIAA1137 | ||
| Type: protein-coding gene | Cytoband: 1q21.3 | ||
| Entrez ID: 57198 | HGNC ID: HGNC:13534 | Ensembl Gene: ENSG00000143515 | OMIM ID: 605867 |
| Drug and gene relationship at DGIdb | |||
Expression of ATP8B2:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | ATP8B2 | 57198 | 226771_at | -0.2458 | 0.7753 | |
| GSE20347 | ATP8B2 | 57198 | 216873_s_at | 0.0507 | 0.5987 | |
| GSE23400 | ATP8B2 | 57198 | 216873_s_at | -0.0493 | 0.2370 | |
| GSE26886 | ATP8B2 | 57198 | 216873_s_at | 0.1693 | 0.1977 | |
| GSE29001 | ATP8B2 | 57198 | 216873_s_at | -0.0478 | 0.7734 | |
| GSE38129 | ATP8B2 | 57198 | 216873_s_at | -0.0497 | 0.5926 | |
| GSE45670 | ATP8B2 | 57198 | 226771_at | -0.9530 | 0.0451 | |
| GSE53622 | ATP8B2 | 57198 | 62960 | 0.2253 | 0.0842 | |
| GSE53624 | ATP8B2 | 57198 | 62960 | 0.4391 | 0.0000 | |
| GSE63941 | ATP8B2 | 57198 | 226771_at | -3.7575 | 0.0036 | |
| GSE77861 | ATP8B2 | 57198 | 216873_s_at | -0.1176 | 0.4833 | |
| GSE97050 | ATP8B2 | 57198 | A_24_P366749 | 0.1691 | 0.5673 | |
| SRP007169 | ATP8B2 | 57198 | RNAseq | 2.9596 | 0.0000 | |
| SRP008496 | ATP8B2 | 57198 | RNAseq | 3.3118 | 0.0000 | |
| SRP064894 | ATP8B2 | 57198 | RNAseq | 0.3716 | 0.2170 | |
| SRP133303 | ATP8B2 | 57198 | RNAseq | 0.3310 | 0.2339 | |
| SRP159526 | ATP8B2 | 57198 | RNAseq | 0.5657 | 0.1311 | |
| SRP193095 | ATP8B2 | 57198 | RNAseq | 1.0188 | 0.0000 | |
| SRP219564 | ATP8B2 | 57198 | RNAseq | 0.2007 | 0.6753 | |
| TCGA | ATP8B2 | 57198 | RNAseq | -0.2425 | 0.0431 |
Upregulated datasets: 3; Downregulated datasets: 1.
Survival by ATP8B2 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of ATP8B2:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | ATP8B2 | 57198 | 14 | 0 | 16 | |
| GSE20123 | ATP8B2 | 57198 | 14 | 0 | 16 | |
| GSE43470 | ATP8B2 | 57198 | 6 | 2 | 35 | |
| GSE46452 | ATP8B2 | 57198 | 2 | 1 | 56 | |
| GSE47630 | ATP8B2 | 57198 | 14 | 0 | 26 | |
| GSE54993 | ATP8B2 | 57198 | 0 | 4 | 66 | |
| GSE54994 | ATP8B2 | 57198 | 16 | 0 | 37 | |
| GSE60625 | ATP8B2 | 57198 | 0 | 0 | 11 | |
| GSE74703 | ATP8B2 | 57198 | 6 | 1 | 29 | |
| GSE74704 | ATP8B2 | 57198 | 7 | 0 | 13 | |
| TCGA | ATP8B2 | 57198 | 38 | 2 | 56 |
Total number of gains: 117; Total number of losses: 10; Total Number of normals: 361.
Somatic mutations of ATP8B2:
Generating mutation plots.
Highly correlated genes for ATP8B2:
Showing top 20/647 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| ATP8B2 | RNF31 | 0.847582 | 3 | 0 | 3 |
| ATP8B2 | ZNF214 | 0.776036 | 3 | 0 | 3 |
| ATP8B2 | TAS2R45 | 0.768857 | 3 | 0 | 3 |
| ATP8B2 | HMCN2 | 0.767516 | 3 | 0 | 3 |
| ATP8B2 | DNM3OS | 0.761617 | 3 | 0 | 3 |
| ATP8B2 | DERL3 | 0.750511 | 4 | 0 | 4 |
| ATP8B2 | EEPD1 | 0.744759 | 4 | 0 | 4 |
| ATP8B2 | LIX1L | 0.743371 | 7 | 0 | 6 |
| ATP8B2 | DMXL2 | 0.741209 | 3 | 0 | 3 |
| ATP8B2 | CLMP | 0.739281 | 7 | 0 | 7 |
| ATP8B2 | LRRK2 | 0.730114 | 3 | 0 | 3 |
| ATP8B2 | GSTT2 | 0.722738 | 3 | 0 | 3 |
| ATP8B2 | DHDDS | 0.720986 | 3 | 0 | 3 |
| ATP8B2 | ZNF579 | 0.717982 | 3 | 0 | 3 |
| ATP8B2 | CLDND2 | 0.71272 | 4 | 0 | 4 |
| ATP8B2 | SERTAD1 | 0.708563 | 3 | 0 | 3 |
| ATP8B2 | C9orf50 | 0.708274 | 4 | 0 | 4 |
| ATP8B2 | RAB34 | 0.706658 | 3 | 0 | 3 |
| ATP8B2 | RAB7B | 0.697087 | 3 | 0 | 3 |
| ATP8B2 | CLEC14A | 0.696232 | 6 | 0 | 5 |
For details and further investigation, click here
