ZNF579

 

Full name: zinc finger protein 579 Alias Symbol: FLJ35453
Type: protein-coding gene Cytoband: 19q13.42
Entrez ID: 163033 HGNC ID: HGNC:26646 Ensembl Gene: ENSG00000218891 OMIM ID: 
Drug and gene relationship at DGIdb

 

Expression of ZNF579:

 

Dataset Gene EntrezID Probe Log2FC Adj.pValue Expression
GSE17351 ZNF579 163033 229140_at 0.3836 0.3104
GSE26886 ZNF579 163033 229140_at 0.6705 0.0000
GSE45670 ZNF579 163033 229140_at -0.0117 0.9081
GSE53622 ZNF579 163033 103700 0.1376 0.0855
GSE53624 ZNF579 163033 103700 0.6881 0.0000
GSE63941 ZNF579 163033 229140_at 0.0661 0.7677
GSE77861 ZNF579 163033 229140_at 0.0004 0.9979
GSE97050 ZNF579 163033 A_33_P3403778 -0.0896 0.7316
SRP007169 ZNF579 163033 RNAseq -0.0392 0.9518
SRP064894 ZNF579 163033 RNAseq 1.3797 0.0004
SRP133303 ZNF579 163033 RNAseq 0.2622 0.1214
SRP159526 ZNF579 163033 RNAseq 1.4478 0.0020
SRP193095 ZNF579 163033 RNAseq 0.3077 0.1434
SRP219564 ZNF579 163033 RNAseq 0.3627 0.4380
TCGA ZNF579 163033 RNAseq -0.2440 0.0026

Upregulated datasets: 2; Downregulated datasets: 0.  


 

Survival by ZNF579 expression:

 

GSE53622GSE53624TCGA

 

Note: Click image to view full size file.  


Copy number change of ZNF579:

 

Dataset Gene EntrezID Gain Loss Normal Detail
GSE15526 ZNF579 163033 3 4 23
GSE20123 ZNF579 163033 3 3 24
GSE43470 ZNF579 163033 3 9 31
GSE46452 ZNF579 163033 45 1 13
GSE47630 ZNF579 163033 8 6 26
GSE54993 ZNF579 163033 17 4 49
GSE54994 ZNF579 163033 4 13 36
GSE60625 ZNF579 163033 9 0 2
GSE74703 ZNF579 163033 3 6 27
GSE74704 ZNF579 163033 3 1 16
TCGA ZNF579 163033 19 14 63

Total number of gains: 117; Total number of losses: 61; Total Number of normals: 310.  


 

Somatic mutations of ZNF579:

 

Generating mutation plots.

 

Highly correlated genes for ZNF579:

 

Showing top 20/713 corelated genes with mean PCC>0.5.
Gene1 Gene2 Mean PCC Num. Datasets Num. PCC<0 Num. PCC>0.5
ZNF579SLC39A30.858656404
ZNF579RNASEH2C0.832371303
ZNF579TRIM470.817796303
ZNF579MORC20.815229303
ZNF579TESK10.81003303
ZNF579CCDC590.799144303
ZNF579LAMA40.780876303
ZNF579ALKBH60.777779303
ZNF579SAFB20.772237404
ZNF579C1orf350.772172303
ZNF579VSTM40.770562303
ZNF579ADAR0.76722303
ZNF579ANP32B0.76557303
ZNF579MEA10.76499303
ZNF579GTPBP60.764924303
ZNF579U2AF20.763276404
ZNF579HAUS70.762945303
ZNF579SRRT0.76223404
ZNF579CHD1L0.761897303
ZNF579INTS10.757553404

For details and further investigation, click here