| Full name: Dmx like 2 | Alias Symbol: RC3|KIAA0856|DFNA71 | ||
| Type: protein-coding gene | Cytoband: 15q21.2 | ||
| Entrez ID: 23312 | HGNC ID: HGNC:2938 | Ensembl Gene: ENSG00000104093 | OMIM ID: 612186 |
| Drug and gene relationship at DGIdb | |||
Expression of DMXL2:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | DMXL2 | 23312 | 212820_at | 0.1002 | 0.8935 | |
| GSE20347 | DMXL2 | 23312 | 212820_at | 1.2651 | 0.0001 | |
| GSE23400 | DMXL2 | 23312 | 215761_at | 0.0927 | 0.0934 | |
| GSE26886 | DMXL2 | 23312 | 212820_at | 1.9089 | 0.0000 | |
| GSE29001 | DMXL2 | 23312 | 212820_at | 0.8034 | 0.0348 | |
| GSE38129 | DMXL2 | 23312 | 212820_at | 0.9046 | 0.0010 | |
| GSE45670 | DMXL2 | 23312 | 212820_at | 0.2425 | 0.4474 | |
| GSE53622 | DMXL2 | 23312 | 54139 | 0.4448 | 0.0001 | |
| GSE53624 | DMXL2 | 23312 | 54139 | 0.7510 | 0.0000 | |
| GSE63941 | DMXL2 | 23312 | 212820_at | 0.1085 | 0.8475 | |
| GSE77861 | DMXL2 | 23312 | 212820_at | 1.0817 | 0.0831 | |
| GSE97050 | DMXL2 | 23312 | A_23_P327361 | 0.7183 | 0.0684 | |
| SRP007169 | DMXL2 | 23312 | RNAseq | 1.9649 | 0.0003 | |
| SRP008496 | DMXL2 | 23312 | RNAseq | 1.8397 | 0.0000 | |
| SRP064894 | DMXL2 | 23312 | RNAseq | 1.2073 | 0.0001 | |
| SRP133303 | DMXL2 | 23312 | RNAseq | 1.0177 | 0.0000 | |
| SRP159526 | DMXL2 | 23312 | RNAseq | 0.2595 | 0.4527 | |
| SRP193095 | DMXL2 | 23312 | RNAseq | 0.6100 | 0.0083 | |
| SRP219564 | DMXL2 | 23312 | RNAseq | 0.8237 | 0.0282 | |
| TCGA | DMXL2 | 23312 | RNAseq | -0.1141 | 0.1710 |
Upregulated datasets: 6; Downregulated datasets: 0.
Survival by DMXL2 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of DMXL2:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | DMXL2 | 23312 | 6 | 3 | 21 | |
| GSE20123 | DMXL2 | 23312 | 6 | 3 | 21 | |
| GSE43470 | DMXL2 | 23312 | 5 | 3 | 35 | |
| GSE46452 | DMXL2 | 23312 | 3 | 7 | 49 | |
| GSE47630 | DMXL2 | 23312 | 8 | 10 | 22 | |
| GSE54993 | DMXL2 | 23312 | 4 | 6 | 60 | |
| GSE54994 | DMXL2 | 23312 | 5 | 7 | 41 | |
| GSE60625 | DMXL2 | 23312 | 4 | 0 | 7 | |
| GSE74703 | DMXL2 | 23312 | 5 | 2 | 29 | |
| GSE74704 | DMXL2 | 23312 | 2 | 3 | 15 | |
| TCGA | DMXL2 | 23312 | 9 | 17 | 70 |
Total number of gains: 57; Total number of losses: 61; Total Number of normals: 370.
Somatic mutations of DMXL2:
Generating mutation plots.
Highly correlated genes for DMXL2:
Showing top 20/1339 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| DMXL2 | GEMIN5 | 0.770644 | 3 | 0 | 3 |
| DMXL2 | FCGR3A | 0.767787 | 3 | 0 | 3 |
| DMXL2 | LSM10 | 0.759683 | 3 | 0 | 3 |
| DMXL2 | ITFG1 | 0.757746 | 4 | 0 | 3 |
| DMXL2 | OCIAD2 | 0.755855 | 3 | 0 | 3 |
| DMXL2 | PGM2L1 | 0.752039 | 3 | 0 | 3 |
| DMXL2 | RNASEH2C | 0.751991 | 3 | 0 | 3 |
| DMXL2 | HPRT1 | 0.747287 | 4 | 0 | 4 |
| DMXL2 | ATP8B2 | 0.741209 | 3 | 0 | 3 |
| DMXL2 | PUS7 | 0.739849 | 3 | 0 | 3 |
| DMXL2 | ASXL2 | 0.739615 | 3 | 0 | 3 |
| DMXL2 | LRRCC1 | 0.734097 | 4 | 0 | 3 |
| DMXL2 | RNF138 | 0.730372 | 3 | 0 | 3 |
| DMXL2 | RBM18 | 0.728018 | 3 | 0 | 3 |
| DMXL2 | SLC44A1 | 0.727016 | 3 | 0 | 3 |
| DMXL2 | PTPRZ1 | 0.725932 | 3 | 0 | 3 |
| DMXL2 | RPL19 | 0.724306 | 3 | 0 | 3 |
| DMXL2 | NCAPD3 | 0.722388 | 3 | 0 | 3 |
| DMXL2 | MRPL9 | 0.721816 | 4 | 0 | 3 |
| DMXL2 | GZF1 | 0.719027 | 3 | 0 | 3 |
For details and further investigation, click here
