| Full name: SERTA domain containing 1 | Alias Symbol: SEI1|TRIP-Br1 | ||
| Type: protein-coding gene | Cytoband: 19q13.1-q13.2 | ||
| Entrez ID: 29950 | HGNC ID: HGNC:17932 | Ensembl Gene: ENSG00000197019 | OMIM ID: 617850 |
| Drug and gene relationship at DGIdb | |||
Expression of SERTAD1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | SERTAD1 | 29950 | 223394_at | -0.4089 | 0.2968 | |
| GSE26886 | SERTAD1 | 29950 | 223394_at | -0.7658 | 0.0001 | |
| GSE45670 | SERTAD1 | 29950 | 223394_at | 0.0897 | 0.7017 | |
| GSE53622 | SERTAD1 | 29950 | 101982 | -0.8114 | 0.0000 | |
| GSE53624 | SERTAD1 | 29950 | 101982 | -0.5919 | 0.0000 | |
| GSE63941 | SERTAD1 | 29950 | 223394_at | -1.2214 | 0.0398 | |
| GSE77861 | SERTAD1 | 29950 | 223394_at | -0.0992 | 0.6251 | |
| GSE97050 | SERTAD1 | 29950 | A_23_P218463 | -0.4720 | 0.3543 | |
| SRP007169 | SERTAD1 | 29950 | RNAseq | -2.0544 | 0.0000 | |
| SRP008496 | SERTAD1 | 29950 | RNAseq | -1.8341 | 0.0000 | |
| SRP064894 | SERTAD1 | 29950 | RNAseq | -0.3084 | 0.3730 | |
| SRP133303 | SERTAD1 | 29950 | RNAseq | -0.1667 | 0.4428 | |
| SRP159526 | SERTAD1 | 29950 | RNAseq | -0.9143 | 0.0129 | |
| SRP193095 | SERTAD1 | 29950 | RNAseq | -0.6117 | 0.0000 | |
| SRP219564 | SERTAD1 | 29950 | RNAseq | -1.4920 | 0.0023 | |
| TCGA | SERTAD1 | 29950 | RNAseq | -0.3830 | 0.0000 |
Upregulated datasets: 0; Downregulated datasets: 4.
Survival by SERTAD1 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of SERTAD1:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | SERTAD1 | 29950 | 6 | 5 | 19 | |
| GSE20123 | SERTAD1 | 29950 | 6 | 4 | 20 | |
| GSE43470 | SERTAD1 | 29950 | 3 | 9 | 31 | |
| GSE46452 | SERTAD1 | 29950 | 48 | 1 | 10 | |
| GSE47630 | SERTAD1 | 29950 | 9 | 5 | 26 | |
| GSE54993 | SERTAD1 | 29950 | 17 | 4 | 49 | |
| GSE54994 | SERTAD1 | 29950 | 8 | 9 | 36 | |
| GSE60625 | SERTAD1 | 29950 | 9 | 0 | 2 | |
| GSE74703 | SERTAD1 | 29950 | 3 | 6 | 27 | |
| GSE74704 | SERTAD1 | 29950 | 6 | 2 | 12 | |
| TCGA | SERTAD1 | 29950 | 14 | 16 | 66 |
Total number of gains: 129; Total number of losses: 61; Total Number of normals: 298.
Somatic mutations of SERTAD1:
Generating mutation plots.
Highly correlated genes for SERTAD1:
Showing top 20/545 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| SERTAD1 | UQCRFS1 | 0.776986 | 3 | 0 | 3 |
| SERTAD1 | GRIK2 | 0.76402 | 3 | 0 | 3 |
| SERTAD1 | DMPK | 0.764015 | 3 | 0 | 3 |
| SERTAD1 | MAGEC1 | 0.761719 | 3 | 0 | 3 |
| SERTAD1 | FILIP1L | 0.747629 | 3 | 0 | 3 |
| SERTAD1 | JUND | 0.745351 | 4 | 0 | 4 |
| SERTAD1 | CACNA1C | 0.742562 | 3 | 0 | 3 |
| SERTAD1 | GSTT2 | 0.738971 | 3 | 0 | 3 |
| SERTAD1 | ID4 | 0.733464 | 3 | 0 | 3 |
| SERTAD1 | NAGA | 0.732191 | 3 | 0 | 3 |
| SERTAD1 | CALY | 0.731691 | 3 | 0 | 3 |
| SERTAD1 | MAP2K3 | 0.731551 | 3 | 0 | 3 |
| SERTAD1 | RAB21 | 0.729679 | 3 | 0 | 3 |
| SERTAD1 | FGFR1 | 0.725702 | 3 | 0 | 3 |
| SERTAD1 | FIBIN | 0.723672 | 3 | 0 | 3 |
| SERTAD1 | FAM122C | 0.722203 | 4 | 0 | 4 |
| SERTAD1 | ZNF407 | 0.720063 | 3 | 0 | 3 |
| SERTAD1 | MTMR3 | 0.717261 | 3 | 0 | 3 |
| SERTAD1 | GJC2 | 0.712604 | 4 | 0 | 4 |
| SERTAD1 | ATP8B2 | 0.708563 | 3 | 0 | 3 |
For details and further investigation, click here
