| Full name: C-type lectin domain containing 14A | Alias Symbol: | ||
| Type: protein-coding gene | Cytoband: 14q21.1 | ||
| Entrez ID: 161198 | HGNC ID: HGNC:19832 | Ensembl Gene: ENSG00000176435 | OMIM ID: 616845 |
| Drug and gene relationship at DGIdb | |||
Expression of CLEC14A:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | CLEC14A | 161198 | 226244_at | -0.1562 | 0.7536 | |
| GSE26886 | CLEC14A | 161198 | 226244_at | -0.0421 | 0.8245 | |
| GSE45670 | CLEC14A | 161198 | 226244_at | -0.6763 | 0.0111 | |
| GSE53622 | CLEC14A | 161198 | 151136 | -0.8041 | 0.0000 | |
| GSE53624 | CLEC14A | 161198 | 151136 | -0.2772 | 0.0700 | |
| GSE63941 | CLEC14A | 161198 | 226244_at | 0.2377 | 0.0883 | |
| GSE77861 | CLEC14A | 161198 | 226244_at | -0.0830 | 0.5977 | |
| GSE97050 | CLEC14A | 161198 | A_24_P215653 | -0.0101 | 0.9765 | |
| SRP007169 | CLEC14A | 161198 | RNAseq | 0.5017 | 0.3990 | |
| SRP064894 | CLEC14A | 161198 | RNAseq | 0.4663 | 0.1672 | |
| SRP133303 | CLEC14A | 161198 | RNAseq | -0.9533 | 0.0000 | |
| SRP159526 | CLEC14A | 161198 | RNAseq | -0.2044 | 0.6770 | |
| SRP193095 | CLEC14A | 161198 | RNAseq | 0.1551 | 0.4774 | |
| SRP219564 | CLEC14A | 161198 | RNAseq | -0.2955 | 0.6231 | |
| TCGA | CLEC14A | 161198 | RNAseq | -0.3853 | 0.0003 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by CLEC14A expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of CLEC14A:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | CLEC14A | 161198 | 11 | 4 | 15 | |
| GSE20123 | CLEC14A | 161198 | 11 | 4 | 15 | |
| GSE43470 | CLEC14A | 161198 | 8 | 3 | 32 | |
| GSE46452 | CLEC14A | 161198 | 18 | 2 | 39 | |
| GSE47630 | CLEC14A | 161198 | 11 | 10 | 19 | |
| GSE54993 | CLEC14A | 161198 | 3 | 9 | 58 | |
| GSE54994 | CLEC14A | 161198 | 19 | 5 | 29 | |
| GSE60625 | CLEC14A | 161198 | 0 | 2 | 9 | |
| GSE74703 | CLEC14A | 161198 | 7 | 3 | 26 | |
| GSE74704 | CLEC14A | 161198 | 5 | 3 | 12 | |
| TCGA | CLEC14A | 161198 | 34 | 14 | 48 |
Total number of gains: 127; Total number of losses: 59; Total Number of normals: 302.
Somatic mutations of CLEC14A:
Generating mutation plots.
Highly correlated genes for CLEC14A:
Showing top 20/565 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| CLEC14A | ICAM2 | 0.836515 | 3 | 0 | 3 |
| CLEC14A | FUNDC2 | 0.819335 | 3 | 0 | 3 |
| CLEC14A | WIPF1 | 0.801997 | 3 | 0 | 3 |
| CLEC14A | CALHM2 | 0.777873 | 3 | 0 | 3 |
| CLEC14A | GIMAP5 | 0.775809 | 3 | 0 | 3 |
| CLEC14A | ECSCR | 0.775389 | 7 | 0 | 6 |
| CLEC14A | DCHS1 | 0.768503 | 4 | 0 | 4 |
| CLEC14A | EBF1 | 0.766133 | 6 | 0 | 5 |
| CLEC14A | A2M | 0.753434 | 6 | 0 | 6 |
| CLEC14A | LYVE1 | 0.751993 | 6 | 0 | 6 |
| CLEC14A | ZNF423 | 0.746723 | 4 | 0 | 4 |
| CLEC14A | CAV3 | 0.739809 | 3 | 0 | 3 |
| CLEC14A | C22orf31 | 0.732341 | 3 | 0 | 3 |
| CLEC14A | PDE4B | 0.730643 | 4 | 0 | 4 |
| CLEC14A | PECAM1 | 0.730205 | 7 | 0 | 7 |
| CLEC14A | VWF | 0.729611 | 6 | 0 | 5 |
| CLEC14A | ST8SIA4 | 0.728949 | 3 | 0 | 3 |
| CLEC14A | CMA1 | 0.727887 | 5 | 0 | 5 |
| CLEC14A | CDH5 | 0.727163 | 7 | 0 | 6 |
| CLEC14A | PPP2R3C | 0.726529 | 3 | 0 | 3 |
For details and further investigation, click here
