| Full name: glutathione S-transferase theta 2 (gene/pseudogene) | Alias Symbol: | ||
| Type: protein-coding gene | Cytoband: 22q11.23 | ||
| Entrez ID: 2953 | HGNC ID: HGNC:4642 | Ensembl Gene: ENSG00000099984 | OMIM ID: 600437 |
| Drug and gene relationship at DGIdb | |||
Expression of GSTT2:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | GSTT2 | 2953 | 205439_at | -0.8728 | 0.2142 | |
| GSE20347 | GSTT2 | 2953 | 205439_at | -0.4764 | 0.0083 | |
| GSE23400 | GSTT2 | 2953 | 205439_at | -0.3726 | 0.0000 | |
| GSE26886 | GSTT2 | 2953 | 205439_at | 0.1967 | 0.7356 | |
| GSE29001 | GSTT2 | 2953 | 205439_at | -1.1652 | 0.0393 | |
| GSE38129 | GSTT2 | 2953 | 205439_at | -0.2776 | 0.2991 | |
| GSE45670 | GSTT2 | 2953 | 205439_at | -1.0479 | 0.0132 | |
| GSE63941 | GSTT2 | 2953 | 205439_at | -1.1586 | 0.2915 | |
| GSE77861 | GSTT2 | 2953 | 205439_at | -0.0965 | 0.9078 | |
| GSE97050 | GSTT2 | 2953 | A_23_P109427 | -0.1166 | 0.7252 | |
| SRP064894 | GSTT2 | 2953 | RNAseq | -0.4580 | 0.2390 | |
| SRP159526 | GSTT2 | 2953 | RNAseq | -0.5985 | 0.3127 | |
| SRP219564 | GSTT2 | 2953 | RNAseq | -1.2187 | 0.1336 | |
| TCGA | GSTT2 | 2953 | RNAseq | -0.2826 | 0.2270 |
Upregulated datasets: 0; Downregulated datasets: 2.
Survival by GSTT2 expression:
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| TCGA |
Note: Click image to view full size file.
Copy number change of GSTT2:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | GSTT2 | 2953 | 5 | 7 | 18 | |
| GSE20123 | GSTT2 | 2953 | 5 | 6 | 19 | |
| GSE43470 | GSTT2 | 2953 | 3 | 6 | 34 | |
| GSE46452 | GSTT2 | 2953 | 32 | 1 | 26 | |
| GSE47630 | GSTT2 | 2953 | 8 | 5 | 27 | |
| GSE54993 | GSTT2 | 2953 | 3 | 6 | 61 | |
| GSE54994 | GSTT2 | 2953 | 11 | 7 | 35 | |
| GSE60625 | GSTT2 | 2953 | 5 | 0 | 6 | |
| GSE74703 | GSTT2 | 2953 | 3 | 5 | 28 | |
| GSE74704 | GSTT2 | 2953 | 2 | 3 | 15 | |
| TCGA | GSTT2 | 2953 | 26 | 15 | 55 |
Total number of gains: 103; Total number of losses: 61; Total Number of normals: 324.
Somatic mutations of GSTT2:
Generating mutation plots.
Highly correlated genes for GSTT2:
Showing top 20/185 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| GSTT2 | INSRR | 0.830368 | 3 | 0 | 3 |
| GSTT2 | ADAM11 | 0.78652 | 3 | 0 | 3 |
| GSTT2 | RNF207 | 0.772733 | 3 | 0 | 3 |
| GSTT2 | SERTAD1 | 0.738971 | 3 | 0 | 3 |
| GSTT2 | IFT46 | 0.737416 | 3 | 0 | 3 |
| GSTT2 | HOXC5 | 0.728739 | 3 | 0 | 3 |
| GSTT2 | AIFM2 | 0.72743 | 3 | 0 | 3 |
| GSTT2 | ATP8B2 | 0.722738 | 3 | 0 | 3 |
| GSTT2 | FGD4 | 0.703643 | 3 | 0 | 3 |
| GSTT2 | SLC46A2 | 0.702303 | 3 | 0 | 3 |
| GSTT2 | RNF31 | 0.694209 | 3 | 0 | 3 |
| GSTT2 | DNAJB5 | 0.686451 | 3 | 0 | 3 |
| GSTT2 | CCNDBP1 | 0.684028 | 3 | 0 | 3 |
| GSTT2 | TNFRSF19 | 0.682423 | 3 | 0 | 3 |
| GSTT2 | VASN | 0.676249 | 3 | 0 | 3 |
| GSTT2 | PRRT3 | 0.675696 | 3 | 0 | 3 |
| GSTT2 | IDH3G | 0.674842 | 3 | 0 | 3 |
| GSTT2 | ULK3 | 0.673888 | 3 | 0 | 3 |
| GSTT2 | RRAD | 0.667547 | 4 | 0 | 3 |
| GSTT2 | EBF1 | 0.666393 | 3 | 0 | 3 |
For details and further investigation, click here
