| Full name: C2 calcium dependent domain containing 2 | Alias Symbol: TMEM24L|DKFZP586F0422|C21orf258 | ||
| Type: protein-coding gene | Cytoband: 21q22.3 | ||
| Entrez ID: 25966 | HGNC ID: HGNC:1266 | Ensembl Gene: ENSG00000157617 | OMIM ID: 617581 |
| Drug and gene relationship at DGIdb | |||
Expression of C2CD2:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | C2CD2 | 25966 | 212875_s_at | 0.4417 | 0.5273 | |
| GSE20347 | C2CD2 | 25966 | 212875_s_at | -0.0487 | 0.7905 | |
| GSE23400 | C2CD2 | 25966 | 212875_s_at | -0.1190 | 0.2287 | |
| GSE26886 | C2CD2 | 25966 | 212875_s_at | -1.1473 | 0.0064 | |
| GSE29001 | C2CD2 | 25966 | 212875_s_at | -0.1636 | 0.6958 | |
| GSE38129 | C2CD2 | 25966 | 212875_s_at | -0.1112 | 0.5430 | |
| GSE45670 | C2CD2 | 25966 | 212875_s_at | 0.0255 | 0.9338 | |
| GSE63941 | C2CD2 | 25966 | 212875_s_at | -1.9539 | 0.0763 | |
| GSE77861 | C2CD2 | 25966 | 212875_s_at | -0.5382 | 0.0377 | |
| GSE97050 | C2CD2 | 25966 | A_24_P940149 | 0.0668 | 0.7337 | |
| SRP007169 | C2CD2 | 25966 | RNAseq | -1.2186 | 0.0021 | |
| SRP008496 | C2CD2 | 25966 | RNAseq | -0.9511 | 0.0003 | |
| SRP064894 | C2CD2 | 25966 | RNAseq | 0.0501 | 0.7395 | |
| SRP133303 | C2CD2 | 25966 | RNAseq | -0.2237 | 0.2696 | |
| SRP159526 | C2CD2 | 25966 | RNAseq | -0.4177 | 0.1541 | |
| SRP193095 | C2CD2 | 25966 | RNAseq | 0.1378 | 0.3725 | |
| SRP219564 | C2CD2 | 25966 | RNAseq | -0.5481 | 0.0362 | |
| TCGA | C2CD2 | 25966 | RNAseq | -0.1957 | 0.0130 |
Upregulated datasets: 0; Downregulated datasets: 2.
Survival by C2CD2 expression:
 |
| TCGA |
Note: Click image to view full size file.
Copy number change of C2CD2:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | C2CD2 | 25966 | 2 | 8 | 20 | |
| GSE20123 | C2CD2 | 25966 | 2 | 8 | 20 | |
| GSE43470 | C2CD2 | 25966 | 0 | 13 | 30 | |
| GSE46452 | C2CD2 | 25966 | 1 | 21 | 37 | |
| GSE47630 | C2CD2 | 25966 | 6 | 17 | 17 | |
| GSE54993 | C2CD2 | 25966 | 8 | 1 | 61 | |
| GSE54994 | C2CD2 | 25966 | 3 | 8 | 42 | |
| GSE60625 | C2CD2 | 25966 | 0 | 0 | 11 | |
| GSE74703 | C2CD2 | 25966 | 0 | 10 | 26 | |
| GSE74704 | C2CD2 | 25966 | 1 | 4 | 15 | |
| TCGA | C2CD2 | 25966 | 7 | 41 | 48 |
Total number of gains: 30; Total number of losses: 131; Total Number of normals: 327.
Somatic mutations of C2CD2:
Generating mutation plots.
Highly correlated genes for C2CD2:
Showing top 20/429 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| C2CD2 | WDR77 | 0.889342 | 3 | 0 | 3 |
| C2CD2 | LARP4 | 0.869465 | 3 | 0 | 3 |
| C2CD2 | ATXN7L3B | 0.836059 | 3 | 0 | 3 |
| C2CD2 | SRSF10 | 0.835668 | 3 | 0 | 3 |
| C2CD2 | PRMT6 | 0.833146 | 3 | 0 | 3 |
| C2CD2 | SBNO1 | 0.815922 | 3 | 0 | 3 |
| C2CD2 | CHCHD1 | 0.802389 | 3 | 0 | 3 |
| C2CD2 | EGLN1 | 0.799424 | 3 | 0 | 3 |
| C2CD2 | TMEM50B | 0.788693 | 3 | 0 | 3 |
| C2CD2 | LRTOMT | 0.778105 | 3 | 0 | 3 |
| C2CD2 | AHCYL2 | 0.776646 | 3 | 0 | 3 |
| C2CD2 | PWWP2A | 0.769703 | 3 | 0 | 3 |
| C2CD2 | KIAA0556 | 0.766832 | 3 | 0 | 3 |
| C2CD2 | HEATR5B | 0.765728 | 3 | 0 | 3 |
| C2CD2 | PUS7L | 0.764097 | 3 | 0 | 3 |
| C2CD2 | ZNF354C | 0.760908 | 3 | 0 | 3 |
| C2CD2 | KIAA2026 | 0.760121 | 3 | 0 | 3 |
| C2CD2 | TMEM219 | 0.757687 | 4 | 0 | 4 |
| C2CD2 | HIPK1 | 0.755117 | 3 | 0 | 3 |
| C2CD2 | PANK1 | 0.750916 | 3 | 0 | 3 |
For details and further investigation, click here
