| Full name: tetratricopeptide repeat domain 31 | Alias Symbol: FLJ12788 | ||
| Type: protein-coding gene | Cytoband: 2p13.1 | ||
| Entrez ID: 64427 | HGNC ID: HGNC:25759 | Ensembl Gene: ENSG00000115282 | OMIM ID: |
| Drug and gene relationship at DGIdb | |||
Expression of TTC31:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | TTC31 | 64427 | 218838_s_at | 0.1249 | 0.5668 | |
| GSE20347 | TTC31 | 64427 | 218838_s_at | 0.4502 | 0.0003 | |
| GSE23400 | TTC31 | 64427 | 218838_s_at | 0.3382 | 0.0000 | |
| GSE26886 | TTC31 | 64427 | 218838_s_at | 0.1566 | 0.3364 | |
| GSE29001 | TTC31 | 64427 | 218838_s_at | 0.3788 | 0.0348 | |
| GSE38129 | TTC31 | 64427 | 218838_s_at | 0.2724 | 0.0098 | |
| GSE45670 | TTC31 | 64427 | 218838_s_at | 0.2626 | 0.0589 | |
| GSE53622 | TTC31 | 64427 | 32885 | 0.3834 | 0.0000 | |
| GSE53624 | TTC31 | 64427 | 22979 | 0.3719 | 0.0000 | |
| GSE63941 | TTC31 | 64427 | 218838_s_at | 0.1846 | 0.6106 | |
| GSE77861 | TTC31 | 64427 | 218838_s_at | 0.3955 | 0.0514 | |
| GSE97050 | TTC31 | 64427 | A_23_P39813 | 0.2622 | 0.2903 | |
| SRP007169 | TTC31 | 64427 | RNAseq | 0.3266 | 0.5286 | |
| SRP008496 | TTC31 | 64427 | RNAseq | 0.0676 | 0.8224 | |
| SRP064894 | TTC31 | 64427 | RNAseq | 0.4016 | 0.0030 | |
| SRP133303 | TTC31 | 64427 | RNAseq | 0.2975 | 0.0286 | |
| SRP159526 | TTC31 | 64427 | RNAseq | 0.4462 | 0.0500 | |
| SRP193095 | TTC31 | 64427 | RNAseq | 0.3271 | 0.0037 | |
| SRP219564 | TTC31 | 64427 | RNAseq | 0.4702 | 0.1630 | |
| TCGA | TTC31 | 64427 | RNAseq | 0.0231 | 0.6678 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by TTC31 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of TTC31:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | TTC31 | 64427 | 9 | 2 | 19 | |
| GSE20123 | TTC31 | 64427 | 10 | 2 | 18 | |
| GSE43470 | TTC31 | 64427 | 4 | 0 | 39 | |
| GSE46452 | TTC31 | 64427 | 2 | 3 | 54 | |
| GSE47630 | TTC31 | 64427 | 7 | 0 | 33 | |
| GSE54993 | TTC31 | 64427 | 0 | 6 | 64 | |
| GSE54994 | TTC31 | 64427 | 10 | 0 | 43 | |
| GSE60625 | TTC31 | 64427 | 0 | 3 | 8 | |
| GSE74703 | TTC31 | 64427 | 4 | 0 | 32 | |
| GSE74704 | TTC31 | 64427 | 8 | 0 | 12 | |
| TCGA | TTC31 | 64427 | 37 | 2 | 57 |
Total number of gains: 91; Total number of losses: 18; Total Number of normals: 379.
Somatic mutations of TTC31:
Generating mutation plots.
Highly correlated genes for TTC31:
Showing top 20/1159 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| TTC31 | DUS3L | 0.757841 | 3 | 0 | 3 |
| TTC31 | ATXN7L3B | 0.747924 | 3 | 0 | 3 |
| TTC31 | RAD18 | 0.72629 | 3 | 0 | 3 |
| TTC31 | IRF2BPL | 0.725268 | 4 | 0 | 4 |
| TTC31 | ENC1 | 0.719109 | 3 | 0 | 3 |
| TTC31 | TEX9 | 0.71732 | 3 | 0 | 3 |
| TTC31 | SLC35B3 | 0.709963 | 3 | 0 | 3 |
| TTC31 | UBXN4 | 0.709811 | 3 | 0 | 3 |
| TTC31 | C12orf66 | 0.706186 | 3 | 0 | 3 |
| TTC31 | NACC1 | 0.703481 | 3 | 0 | 3 |
| TTC31 | FOXC2 | 0.701794 | 3 | 0 | 3 |
| TTC31 | CCNT1 | 0.700079 | 4 | 0 | 3 |
| TTC31 | DEXI | 0.697649 | 3 | 0 | 3 |
| TTC31 | RNF26 | 0.694027 | 3 | 0 | 3 |
| TTC31 | KLHL24 | 0.685154 | 3 | 0 | 3 |
| TTC31 | NOC2L | 0.678217 | 3 | 0 | 3 |
| TTC31 | PSMD9 | 0.677213 | 3 | 0 | 3 |
| TTC31 | USP37 | 0.676963 | 5 | 0 | 5 |
| TTC31 | HTRA2 | 0.67661 | 10 | 0 | 10 |
| TTC31 | COMMD7 | 0.67224 | 4 | 0 | 3 |
For details and further investigation, click here
