| Full name: NOC3 like DNA replication regulator | Alias Symbol: AD24|FLJ12820|FAD24 | ||
| Type: protein-coding gene | Cytoband: 10q23.33 | ||
| Entrez ID: 64318 | HGNC ID: HGNC:24034 | Ensembl Gene: ENSG00000173145 | OMIM ID: 610769 |
| Drug and gene relationship at DGIdb | |||
Screen Evidence:
| |||
Expression of NOC3L:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | NOC3L | 64318 | 218889_at | 0.4810 | 0.1933 | |
| GSE20347 | NOC3L | 64318 | 218889_at | 0.3815 | 0.0267 | |
| GSE23400 | NOC3L | 64318 | 218889_at | 0.6886 | 0.0000 | |
| GSE26886 | NOC3L | 64318 | 218889_at | 0.3905 | 0.0794 | |
| GSE29001 | NOC3L | 64318 | 218889_at | 0.4937 | 0.1248 | |
| GSE38129 | NOC3L | 64318 | 218889_at | 0.5603 | 0.0006 | |
| GSE45670 | NOC3L | 64318 | 218889_at | 0.2800 | 0.0688 | |
| GSE53622 | NOC3L | 64318 | 42615 | -0.3901 | 0.0000 | |
| GSE53624 | NOC3L | 64318 | 42615 | 0.3256 | 0.0000 | |
| GSE63941 | NOC3L | 64318 | 218889_at | 0.0372 | 0.9504 | |
| GSE77861 | NOC3L | 64318 | 218889_at | 0.3258 | 0.4115 | |
| GSE97050 | NOC3L | 64318 | A_23_P202496 | -0.2941 | 0.2509 | |
| SRP007169 | NOC3L | 64318 | RNAseq | 0.1681 | 0.6817 | |
| SRP008496 | NOC3L | 64318 | RNAseq | 0.3228 | 0.1794 | |
| SRP064894 | NOC3L | 64318 | RNAseq | -0.0605 | 0.7568 | |
| SRP133303 | NOC3L | 64318 | RNAseq | 0.4170 | 0.0042 | |
| SRP159526 | NOC3L | 64318 | RNAseq | -0.0359 | 0.9067 | |
| SRP193095 | NOC3L | 64318 | RNAseq | 0.1042 | 0.4371 | |
| SRP219564 | NOC3L | 64318 | RNAseq | 0.2885 | 0.3306 | |
| TCGA | NOC3L | 64318 | RNAseq | 0.1382 | 0.0144 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by NOC3L expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of NOC3L:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | NOC3L | 64318 | 1 | 8 | 21 | |
| GSE20123 | NOC3L | 64318 | 1 | 7 | 22 | |
| GSE43470 | NOC3L | 64318 | 0 | 7 | 36 | |
| GSE46452 | NOC3L | 64318 | 0 | 11 | 48 | |
| GSE47630 | NOC3L | 64318 | 2 | 14 | 24 | |
| GSE54993 | NOC3L | 64318 | 7 | 0 | 63 | |
| GSE54994 | NOC3L | 64318 | 2 | 10 | 41 | |
| GSE60625 | NOC3L | 64318 | 0 | 0 | 11 | |
| GSE74703 | NOC3L | 64318 | 0 | 5 | 31 | |
| GSE74704 | NOC3L | 64318 | 0 | 4 | 16 | |
| TCGA | NOC3L | 64318 | 6 | 26 | 64 |
Total number of gains: 19; Total number of losses: 92; Total Number of normals: 377.
Somatic mutations of NOC3L:
Generating mutation plots.
Highly correlated genes for NOC3L:
Showing top 20/1069 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| NOC3L | DMAP1 | 0.802573 | 3 | 0 | 3 |
| NOC3L | MCM3AP | 0.80051 | 3 | 0 | 3 |
| NOC3L | ATXN7L3B | 0.778903 | 3 | 0 | 3 |
| NOC3L | ASTE1 | 0.778612 | 3 | 0 | 3 |
| NOC3L | TMEM201 | 0.773671 | 3 | 0 | 3 |
| NOC3L | LCOR | 0.770546 | 3 | 0 | 3 |
| NOC3L | KLHL15 | 0.767975 | 3 | 0 | 3 |
| NOC3L | E4F1 | 0.767365 | 3 | 0 | 3 |
| NOC3L | DNAJC9 | 0.760649 | 8 | 0 | 8 |
| NOC3L | TAF1C | 0.754791 | 3 | 0 | 3 |
| NOC3L | ZNF432 | 0.751705 | 3 | 0 | 3 |
| NOC3L | HCFC1 | 0.74954 | 3 | 0 | 3 |
| NOC3L | UHRF1BP1 | 0.74888 | 3 | 0 | 3 |
| NOC3L | GATAD2B | 0.741588 | 3 | 0 | 3 |
| NOC3L | ZSCAN29 | 0.738174 | 3 | 0 | 3 |
| NOC3L | KIAA2013 | 0.735236 | 3 | 0 | 3 |
| NOC3L | ZFR | 0.73003 | 4 | 0 | 4 |
| NOC3L | TAS2R19 | 0.725323 | 3 | 0 | 3 |
| NOC3L | VGLL4 | 0.721952 | 3 | 0 | 3 |
| NOC3L | MRPS26 | 0.720366 | 3 | 0 | 3 |
For details and further investigation, click here
