| Full name: solute carrier family 9 member A8 | Alias Symbol: KIAA0939|NHE8 | ||
| Type: protein-coding gene | Cytoband: 20q13.13 | ||
| Entrez ID: 23315 | HGNC ID: HGNC:20728 | Ensembl Gene: ENSG00000197818 | OMIM ID: 612730 |
| Drug and gene relationship at DGIdb | |||
Expression of SLC9A8:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | SLC9A8 | 23315 | 212947_at | 0.0556 | 0.9471 | |
| GSE20347 | SLC9A8 | 23315 | 212947_at | -0.2300 | 0.2275 | |
| GSE23400 | SLC9A8 | 23315 | 212947_at | -0.1529 | 0.0517 | |
| GSE26886 | SLC9A8 | 23315 | 212947_at | -0.7778 | 0.0019 | |
| GSE29001 | SLC9A8 | 23315 | 212947_at | -0.2039 | 0.4712 | |
| GSE38129 | SLC9A8 | 23315 | 212947_at | -0.1463 | 0.3329 | |
| GSE45670 | SLC9A8 | 23315 | 212947_at | -0.3790 | 0.0231 | |
| GSE53622 | SLC9A8 | 23315 | 10564 | -0.7818 | 0.0000 | |
| GSE53624 | SLC9A8 | 23315 | 10564 | -0.6850 | 0.0000 | |
| GSE63941 | SLC9A8 | 23315 | 212947_at | -0.2182 | 0.5365 | |
| GSE77861 | SLC9A8 | 23315 | 212947_at | -0.1438 | 0.4037 | |
| GSE97050 | SLC9A8 | 23315 | A_24_P58054 | -0.0534 | 0.8515 | |
| SRP007169 | SLC9A8 | 23315 | RNAseq | -1.8124 | 0.0005 | |
| SRP008496 | SLC9A8 | 23315 | RNAseq | -1.8227 | 0.0000 | |
| SRP064894 | SLC9A8 | 23315 | RNAseq | -0.6180 | 0.0004 | |
| SRP133303 | SLC9A8 | 23315 | RNAseq | -0.6382 | 0.0000 | |
| SRP159526 | SLC9A8 | 23315 | RNAseq | -1.0173 | 0.0009 | |
| SRP193095 | SLC9A8 | 23315 | RNAseq | -0.4161 | 0.0006 | |
| SRP219564 | SLC9A8 | 23315 | RNAseq | -0.4660 | 0.1828 | |
| TCGA | SLC9A8 | 23315 | RNAseq | -0.1849 | 0.0001 |
Upregulated datasets: 0; Downregulated datasets: 3.
Survival by SLC9A8 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of SLC9A8:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | SLC9A8 | 23315 | 17 | 2 | 11 | |
| GSE20123 | SLC9A8 | 23315 | 17 | 2 | 11 | |
| GSE43470 | SLC9A8 | 23315 | 13 | 0 | 30 | |
| GSE46452 | SLC9A8 | 23315 | 29 | 0 | 30 | |
| GSE47630 | SLC9A8 | 23315 | 24 | 1 | 15 | |
| GSE54993 | SLC9A8 | 23315 | 0 | 17 | 53 | |
| GSE54994 | SLC9A8 | 23315 | 27 | 0 | 26 | |
| GSE60625 | SLC9A8 | 23315 | 0 | 0 | 11 | |
| GSE74703 | SLC9A8 | 23315 | 11 | 0 | 25 | |
| GSE74704 | SLC9A8 | 23315 | 13 | 0 | 7 | |
| TCGA | SLC9A8 | 23315 | 46 | 3 | 47 |
Total number of gains: 197; Total number of losses: 25; Total Number of normals: 266.
Somatic mutations of SLC9A8:
Generating mutation plots.
Highly correlated genes for SLC9A8:
Showing top 20/773 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| SLC9A8 | ZNF776 | 0.804129 | 3 | 0 | 3 |
| SLC9A8 | ATXN7L3B | 0.756254 | 3 | 0 | 3 |
| SLC9A8 | PLEKHA2 | 0.73422 | 3 | 0 | 3 |
| SLC9A8 | KDM4A | 0.731068 | 3 | 0 | 3 |
| SLC9A8 | GCDH | 0.724398 | 3 | 0 | 3 |
| SLC9A8 | PEX11B | 0.72155 | 6 | 0 | 6 |
| SLC9A8 | NFXL1 | 0.717589 | 3 | 0 | 3 |
| SLC9A8 | NAA25 | 0.710593 | 3 | 0 | 3 |
| SLC9A8 | VPS26B | 0.710154 | 4 | 0 | 4 |
| SLC9A8 | KDM2B | 0.708124 | 4 | 0 | 4 |
| SLC9A8 | CYTH2 | 0.704379 | 3 | 0 | 3 |
| SLC9A8 | PRDM10 | 0.702022 | 4 | 0 | 4 |
| SLC9A8 | NUB1 | 0.700116 | 3 | 0 | 3 |
| SLC9A8 | CPT2 | 0.699389 | 3 | 0 | 3 |
| SLC9A8 | FIS1 | 0.697323 | 3 | 0 | 3 |
| SLC9A8 | ZNF416 | 0.696195 | 4 | 0 | 3 |
| SLC9A8 | CRBN | 0.6961 | 3 | 0 | 3 |
| SLC9A8 | ADAM15 | 0.695956 | 3 | 0 | 3 |
| SLC9A8 | OXSM | 0.695362 | 3 | 0 | 3 |
| SLC9A8 | ABI1 | 0.693471 | 3 | 0 | 3 |
For details and further investigation, click here
