| Full name: transforming growth factor beta regulator 4 | Alias Symbol: Cpr2|KIAA0948|H_TD2522F11.8|FASTKD4 | ||
| Type: protein-coding gene | Cytoband: 7p13 | ||
| Entrez ID: 9238 | HGNC ID: HGNC:17443 | Ensembl Gene: ENSG00000136270 | OMIM ID: 611325 |
| Drug and gene relationship at DGIdb | |||
Screen Evidence:
| |||
Expression of TBRG4:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | TBRG4 | 9238 | 220961_s_at | 0.2944 | 0.6675 | |
| GSE20347 | TBRG4 | 9238 | 220961_s_at | 0.2141 | 0.0149 | |
| GSE23400 | TBRG4 | 9238 | 220961_s_at | -0.0042 | 0.9078 | |
| GSE26886 | TBRG4 | 9238 | 220961_s_at | -0.0808 | 0.7323 | |
| GSE29001 | TBRG4 | 9238 | 220961_s_at | 0.2035 | 0.2877 | |
| GSE38129 | TBRG4 | 9238 | 220961_s_at | 0.1074 | 0.2858 | |
| GSE45670 | TBRG4 | 9238 | 220961_s_at | 0.2958 | 0.0923 | |
| GSE53622 | TBRG4 | 9238 | 29553 | 0.5192 | 0.0000 | |
| GSE53624 | TBRG4 | 9238 | 29553 | 0.8857 | 0.0000 | |
| GSE63941 | TBRG4 | 9238 | 220961_s_at | 0.2018 | 0.7706 | |
| GSE77861 | TBRG4 | 9238 | 220961_s_at | 0.0048 | 0.9739 | |
| GSE97050 | TBRG4 | 9238 | A_23_P215658 | -0.0943 | 0.8932 | |
| SRP007169 | TBRG4 | 9238 | RNAseq | 0.2211 | 0.4700 | |
| SRP008496 | TBRG4 | 9238 | RNAseq | 0.5223 | 0.0545 | |
| SRP064894 | TBRG4 | 9238 | RNAseq | 0.9055 | 0.0001 | |
| SRP133303 | TBRG4 | 9238 | RNAseq | 0.6799 | 0.0001 | |
| SRP159526 | TBRG4 | 9238 | RNAseq | 0.7791 | 0.0064 | |
| SRP193095 | TBRG4 | 9238 | RNAseq | 0.5898 | 0.0000 | |
| SRP219564 | TBRG4 | 9238 | RNAseq | 0.5379 | 0.1475 | |
| TCGA | TBRG4 | 9238 | RNAseq | 0.2198 | 0.0001 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by TBRG4 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of TBRG4:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | TBRG4 | 9238 | 13 | 0 | 17 | |
| GSE20123 | TBRG4 | 9238 | 12 | 0 | 18 | |
| GSE43470 | TBRG4 | 9238 | 4 | 0 | 39 | |
| GSE46452 | TBRG4 | 9238 | 11 | 1 | 47 | |
| GSE47630 | TBRG4 | 9238 | 8 | 1 | 31 | |
| GSE54993 | TBRG4 | 9238 | 0 | 8 | 62 | |
| GSE54994 | TBRG4 | 9238 | 16 | 3 | 34 | |
| GSE60625 | TBRG4 | 9238 | 0 | 0 | 11 | |
| GSE74703 | TBRG4 | 9238 | 4 | 0 | 32 | |
| GSE74704 | TBRG4 | 9238 | 6 | 0 | 14 | |
| TCGA | TBRG4 | 9238 | 50 | 7 | 39 |
Total number of gains: 124; Total number of losses: 20; Total Number of normals: 344.
Somatic mutations of TBRG4:
Generating mutation plots.
Highly correlated genes for TBRG4:
Showing top 20/556 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| TBRG4 | RAD18 | 0.791992 | 3 | 0 | 3 |
| TBRG4 | LRRC34 | 0.787051 | 3 | 0 | 3 |
| TBRG4 | DAP3 | 0.783091 | 3 | 0 | 3 |
| TBRG4 | DHX37 | 0.780142 | 3 | 0 | 3 |
| TBRG4 | EBNA1BP2 | 0.771388 | 3 | 0 | 3 |
| TBRG4 | ERP27 | 0.767087 | 3 | 0 | 3 |
| TBRG4 | MRPL11 | 0.75833 | 4 | 0 | 4 |
| TBRG4 | KTI12 | 0.755486 | 3 | 0 | 3 |
| TBRG4 | ZSCAN29 | 0.753325 | 4 | 0 | 4 |
| TBRG4 | DHX57 | 0.752819 | 3 | 0 | 3 |
| TBRG4 | LYAR | 0.752661 | 3 | 0 | 3 |
| TBRG4 | TTC4 | 0.747522 | 4 | 0 | 4 |
| TBRG4 | ALG3 | 0.746746 | 4 | 0 | 4 |
| TBRG4 | ATXN7L3B | 0.743085 | 3 | 0 | 3 |
| TBRG4 | RNASEH2A | 0.741059 | 3 | 0 | 3 |
| TBRG4 | PMS2 | 0.740097 | 3 | 0 | 3 |
| TBRG4 | KLHL24 | 0.734738 | 3 | 0 | 3 |
| TBRG4 | AGK | 0.731368 | 4 | 0 | 3 |
| TBRG4 | DEXI | 0.724788 | 3 | 0 | 3 |
| TBRG4 | C2CD2 | 0.722181 | 3 | 0 | 3 |
For details and further investigation, click here
