| Full name: bromodomain and PHD finger containing 3 | Alias Symbol: KIAA1286 | ||
| Type: protein-coding gene | Cytoband: 6p21.31 | ||
| Entrez ID: 27154 | HGNC ID: HGNC:14256 | Ensembl Gene: ENSG00000096070 | OMIM ID: 616856 |
| Drug and gene relationship at DGIdb | |||
Expression of BRPF3:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | BRPF3 | 27154 | 225217_s_at | 0.2346 | 0.6858 | |
| GSE26886 | BRPF3 | 27154 | 225217_s_at | -0.0472 | 0.8665 | |
| GSE45670 | BRPF3 | 27154 | 225217_s_at | 0.0276 | 0.8802 | |
| GSE53622 | BRPF3 | 27154 | 9244 | 0.3726 | 0.0000 | |
| GSE53624 | BRPF3 | 27154 | 9244 | 0.4074 | 0.0000 | |
| GSE63941 | BRPF3 | 27154 | 225217_s_at | -1.1243 | 0.0103 | |
| GSE77861 | BRPF3 | 27154 | 1565843_s_at | -0.0644 | 0.5715 | |
| GSE97050 | BRPF3 | 27154 | A_33_P3375077 | 0.2124 | 0.4324 | |
| SRP007169 | BRPF3 | 27154 | RNAseq | 0.0318 | 0.9390 | |
| SRP008496 | BRPF3 | 27154 | RNAseq | 0.1060 | 0.7169 | |
| SRP064894 | BRPF3 | 27154 | RNAseq | 0.0323 | 0.8840 | |
| SRP133303 | BRPF3 | 27154 | RNAseq | 0.2002 | 0.2754 | |
| SRP159526 | BRPF3 | 27154 | RNAseq | 0.2417 | 0.2770 | |
| SRP193095 | BRPF3 | 27154 | RNAseq | 0.1600 | 0.2184 | |
| SRP219564 | BRPF3 | 27154 | RNAseq | -0.0721 | 0.8454 | |
| TCGA | BRPF3 | 27154 | RNAseq | -0.2674 | 0.0000 |
Upregulated datasets: 0; Downregulated datasets: 1.
Survival by BRPF3 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of BRPF3:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | BRPF3 | 27154 | 5 | 0 | 25 | |
| GSE20123 | BRPF3 | 27154 | 5 | 0 | 25 | |
| GSE43470 | BRPF3 | 27154 | 5 | 1 | 37 | |
| GSE46452 | BRPF3 | 27154 | 2 | 9 | 48 | |
| GSE47630 | BRPF3 | 27154 | 8 | 4 | 28 | |
| GSE54993 | BRPF3 | 27154 | 3 | 1 | 66 | |
| GSE54994 | BRPF3 | 27154 | 11 | 4 | 38 | |
| GSE60625 | BRPF3 | 27154 | 1 | 0 | 10 | |
| GSE74703 | BRPF3 | 27154 | 5 | 0 | 31 | |
| GSE74704 | BRPF3 | 27154 | 2 | 0 | 18 | |
| TCGA | BRPF3 | 27154 | 15 | 15 | 66 |
Total number of gains: 62; Total number of losses: 34; Total Number of normals: 392.
Somatic mutations of BRPF3:
Generating mutation plots.
Highly correlated genes for BRPF3:
Showing top 20/215 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| BRPF3 | KBTBD8 | 0.763682 | 3 | 0 | 3 |
| BRPF3 | INSR | 0.742786 | 3 | 0 | 3 |
| BRPF3 | GTPBP6 | 0.723739 | 3 | 0 | 3 |
| BRPF3 | SF1 | 0.721793 | 3 | 0 | 3 |
| BRPF3 | ARHGAP33 | 0.720727 | 3 | 0 | 3 |
| BRPF3 | LRP3 | 0.710788 | 3 | 0 | 3 |
| BRPF3 | FBXO6 | 0.709821 | 3 | 0 | 3 |
| BRPF3 | FBXO31 | 0.70154 | 3 | 0 | 3 |
| BRPF3 | GLB1L2 | 0.69877 | 3 | 0 | 3 |
| BRPF3 | FAM160B1 | 0.695557 | 3 | 0 | 3 |
| BRPF3 | ZDHHC14 | 0.694981 | 3 | 0 | 3 |
| BRPF3 | TRIM8 | 0.693798 | 4 | 0 | 4 |
| BRPF3 | RSAD1 | 0.692223 | 3 | 0 | 3 |
| BRPF3 | ARID1B | 0.684574 | 3 | 0 | 3 |
| BRPF3 | SLC39A13 | 0.684094 | 4 | 0 | 3 |
| BRPF3 | SLC26A11 | 0.68316 | 3 | 0 | 3 |
| BRPF3 | CAND2 | 0.674832 | 3 | 0 | 3 |
| BRPF3 | SKI | 0.672522 | 4 | 0 | 4 |
| BRPF3 | PTGER2 | 0.669626 | 3 | 0 | 3 |
| BRPF3 | FAM43B | 0.668967 | 3 | 0 | 3 |
For details and further investigation, click here
