| Full name: Rho GTPase activating protein 33 | Alias Symbol: FLJ39019|TCGAP | ||
| Type: protein-coding gene | Cytoband: 19q13.12 | ||
| Entrez ID: 115703 | HGNC ID: HGNC:23085 | Ensembl Gene: ENSG00000004777 | OMIM ID: 614902 |
| Drug and gene relationship at DGIdb | |||
Expression of ARHGAP33:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | ARHGAP33 | 115703 | 213827_at | -0.0213 | 0.9766 | |
| GSE20347 | ARHGAP33 | 115703 | 213827_at | -0.0005 | 0.9972 | |
| GSE23400 | ARHGAP33 | 115703 | 213827_at | -0.1066 | 0.0260 | |
| GSE26886 | ARHGAP33 | 115703 | 213827_at | -0.0211 | 0.8795 | |
| GSE29001 | ARHGAP33 | 115703 | 213827_at | -0.1337 | 0.6890 | |
| GSE38129 | ARHGAP33 | 115703 | 213827_at | -0.0013 | 0.9927 | |
| GSE45670 | ARHGAP33 | 115703 | 213827_at | -0.0147 | 0.9044 | |
| GSE53622 | ARHGAP33 | 115703 | 82074 | 0.0308 | 0.6445 | |
| GSE53624 | ARHGAP33 | 115703 | 82074 | -0.1982 | 0.0086 | |
| GSE63941 | ARHGAP33 | 115703 | 213827_at | -0.0413 | 0.8530 | |
| GSE77861 | ARHGAP33 | 115703 | 213827_at | -0.2287 | 0.0643 | |
| GSE97050 | ARHGAP33 | 115703 | A_33_P3313411 | -0.1091 | 0.7575 | |
| SRP064894 | ARHGAP33 | 115703 | RNAseq | 0.4955 | 0.0925 | |
| SRP133303 | ARHGAP33 | 115703 | RNAseq | -0.0182 | 0.9393 | |
| SRP159526 | ARHGAP33 | 115703 | RNAseq | 1.2515 | 0.0478 | |
| SRP193095 | ARHGAP33 | 115703 | RNAseq | 0.5803 | 0.0230 | |
| SRP219564 | ARHGAP33 | 115703 | RNAseq | 0.0581 | 0.8564 | |
| TCGA | ARHGAP33 | 115703 | RNAseq | 0.1727 | 0.1082 |
Upregulated datasets: 1; Downregulated datasets: 0.
Survival by ARHGAP33 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of ARHGAP33:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | ARHGAP33 | 115703 | 7 | 4 | 19 | |
| GSE20123 | ARHGAP33 | 115703 | 7 | 3 | 20 | |
| GSE43470 | ARHGAP33 | 115703 | 3 | 7 | 33 | |
| GSE46452 | ARHGAP33 | 115703 | 48 | 1 | 10 | |
| GSE47630 | ARHGAP33 | 115703 | 9 | 5 | 26 | |
| GSE54993 | ARHGAP33 | 115703 | 17 | 3 | 50 | |
| GSE54994 | ARHGAP33 | 115703 | 6 | 9 | 38 | |
| GSE60625 | ARHGAP33 | 115703 | 9 | 0 | 2 | |
| GSE74703 | ARHGAP33 | 115703 | 3 | 4 | 29 | |
| GSE74704 | ARHGAP33 | 115703 | 6 | 1 | 13 | |
| TCGA | ARHGAP33 | 115703 | 22 | 10 | 64 |
Total number of gains: 137; Total number of losses: 47; Total Number of normals: 304.
Somatic mutations of ARHGAP33:
Generating mutation plots.
Highly correlated genes for ARHGAP33:
Showing top 20/253 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| ARHGAP33 | PLEKHG5 | 0.808091 | 3 | 0 | 3 |
| ARHGAP33 | SFTPA2 | 0.744195 | 3 | 0 | 3 |
| ARHGAP33 | CLDN19 | 0.741276 | 3 | 0 | 3 |
| ARHGAP33 | ZNF331 | 0.73061 | 3 | 0 | 3 |
| ARHGAP33 | BRPF3 | 0.720727 | 3 | 0 | 3 |
| ARHGAP33 | CHMP6 | 0.718389 | 3 | 0 | 3 |
| ARHGAP33 | RIBC1 | 0.704555 | 3 | 0 | 3 |
| ARHGAP33 | CSRNP1 | 0.698929 | 3 | 0 | 3 |
| ARHGAP33 | PVALB | 0.695678 | 3 | 0 | 3 |
| ARHGAP33 | KIRREL2 | 0.693461 | 3 | 0 | 3 |
| ARHGAP33 | IQSEC2 | 0.693333 | 5 | 0 | 4 |
| ARHGAP33 | NFIX | 0.687791 | 3 | 0 | 3 |
| ARHGAP33 | CCDC78 | 0.687192 | 3 | 0 | 3 |
| ARHGAP33 | CCNB3 | 0.67017 | 4 | 0 | 4 |
| ARHGAP33 | CORO6 | 0.669835 | 3 | 0 | 3 |
| ARHGAP33 | DEFB132 | 0.66778 | 3 | 0 | 3 |
| ARHGAP33 | PNMA6A | 0.664148 | 3 | 0 | 3 |
| ARHGAP33 | SLC4A1 | 0.654481 | 4 | 0 | 3 |
| ARHGAP33 | ZNF316 | 0.654402 | 3 | 0 | 3 |
| ARHGAP33 | CHAT | 0.651908 | 4 | 0 | 4 |
For details and further investigation, click here
