| Full name: kelch repeat and BTB domain containing 8 | Alias Symbol: TA-KRP|KIAA1842 | ||
| Type: protein-coding gene | Cytoband: 3p14.1 | ||
| Entrez ID: 84541 | HGNC ID: HGNC:30691 | Ensembl Gene: ENSG00000163376 | OMIM ID: 616607 |
| Drug and gene relationship at DGIdb | |||
Expression of KBTBD8:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | KBTBD8 | 84541 | 239835_at | 0.4883 | 0.4861 | |
| GSE26886 | KBTBD8 | 84541 | 239835_at | -1.5723 | 0.0000 | |
| GSE45670 | KBTBD8 | 84541 | 239835_at | 0.3458 | 0.1563 | |
| GSE53622 | KBTBD8 | 84541 | 93245 | -0.7683 | 0.0000 | |
| GSE53624 | KBTBD8 | 84541 | 93245 | -0.3707 | 0.0139 | |
| GSE63941 | KBTBD8 | 84541 | 239835_at | -1.4728 | 0.0185 | |
| GSE77861 | KBTBD8 | 84541 | 239835_at | -0.1272 | 0.2035 | |
| GSE97050 | KBTBD8 | 84541 | A_23_P431252 | -0.0499 | 0.8468 | |
| SRP007169 | KBTBD8 | 84541 | RNAseq | -0.2143 | 0.7285 | |
| SRP064894 | KBTBD8 | 84541 | RNAseq | -0.0323 | 0.9069 | |
| SRP133303 | KBTBD8 | 84541 | RNAseq | 0.2935 | 0.2902 | |
| SRP159526 | KBTBD8 | 84541 | RNAseq | -1.0995 | 0.0579 | |
| SRP193095 | KBTBD8 | 84541 | RNAseq | -0.3488 | 0.1132 | |
| SRP219564 | KBTBD8 | 84541 | RNAseq | -0.2336 | 0.7733 | |
| TCGA | KBTBD8 | 84541 | RNAseq | -0.3982 | 0.0137 |
Upregulated datasets: 0; Downregulated datasets: 2.
Survival by KBTBD8 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of KBTBD8:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | KBTBD8 | 84541 | 1 | 18 | 11 | |
| GSE20123 | KBTBD8 | 84541 | 1 | 18 | 11 | |
| GSE43470 | KBTBD8 | 84541 | 0 | 20 | 23 | |
| GSE46452 | KBTBD8 | 84541 | 2 | 17 | 40 | |
| GSE47630 | KBTBD8 | 84541 | 2 | 23 | 15 | |
| GSE54993 | KBTBD8 | 84541 | 5 | 2 | 63 | |
| GSE54994 | KBTBD8 | 84541 | 1 | 33 | 19 | |
| GSE60625 | KBTBD8 | 84541 | 3 | 1 | 7 | |
| GSE74703 | KBTBD8 | 84541 | 0 | 16 | 20 | |
| GSE74704 | KBTBD8 | 84541 | 1 | 12 | 7 | |
| TCGA | KBTBD8 | 84541 | 0 | 78 | 18 |
Total number of gains: 16; Total number of losses: 238; Total Number of normals: 234.
Somatic mutations of KBTBD8:
Generating mutation plots.
Highly correlated genes for KBTBD8:
Showing top 20/446 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| KBTBD8 | FAM160B1 | 0.782931 | 3 | 0 | 3 |
| KBTBD8 | BRPF3 | 0.763682 | 3 | 0 | 3 |
| KBTBD8 | EIF1AY | 0.750544 | 3 | 0 | 3 |
| KBTBD8 | KDM5D | 0.74775 | 3 | 0 | 3 |
| KBTBD8 | C19orf18 | 0.746297 | 3 | 0 | 3 |
| KBTBD8 | SIDT2 | 0.74089 | 3 | 0 | 3 |
| KBTBD8 | ECSCR | 0.731755 | 3 | 0 | 3 |
| KBTBD8 | BTN2A1 | 0.731565 | 3 | 0 | 3 |
| KBTBD8 | CNRIP1 | 0.724717 | 4 | 0 | 4 |
| KBTBD8 | STAT5A | 0.719116 | 5 | 0 | 5 |
| KBTBD8 | HDHD2 | 0.718004 | 4 | 0 | 4 |
| KBTBD8 | RBM7 | 0.713324 | 4 | 0 | 3 |
| KBTBD8 | ZNF844 | 0.709451 | 4 | 0 | 4 |
| KBTBD8 | ZNF322 | 0.707597 | 3 | 0 | 3 |
| KBTBD8 | HBS1L | 0.701039 | 3 | 0 | 3 |
| KBTBD8 | ZNF441 | 0.699438 | 4 | 0 | 3 |
| KBTBD8 | PARD3B | 0.698163 | 3 | 0 | 3 |
| KBTBD8 | IKZF4 | 0.697073 | 3 | 0 | 3 |
| KBTBD8 | CACNA2D1 | 0.69655 | 3 | 0 | 3 |
| KBTBD8 | SYTL4 | 0.696462 | 3 | 0 | 3 |
For details and further investigation, click here
