| Full name: F-box protein 6 | Alias Symbol: FBX6|FBG2|FBS2|Fbx6b | ||
| Type: protein-coding gene | Cytoband: 1p36.22 | ||
| Entrez ID: 26270 | HGNC ID: HGNC:13585 | Ensembl Gene: ENSG00000116663 | OMIM ID: 605647 |
| Drug and gene relationship at DGIdb | |||
Expression of FBXO6:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | FBXO6 | 26270 | 231769_at | 0.4838 | 0.6034 | |
| GSE26886 | FBXO6 | 26270 | 231769_at | 0.4675 | 0.2669 | |
| GSE45670 | FBXO6 | 26270 | 231769_at | 1.0967 | 0.0002 | |
| GSE53622 | FBXO6 | 26270 | 40661 | 0.5303 | 0.0000 | |
| GSE53624 | FBXO6 | 26270 | 40661 | 0.5392 | 0.0000 | |
| GSE63941 | FBXO6 | 26270 | 231769_at | -0.7228 | 0.3841 | |
| GSE77861 | FBXO6 | 26270 | 231769_at | -0.4282 | 0.1637 | |
| GSE97050 | FBXO6 | 26270 | A_23_P97064 | 0.4361 | 0.1756 | |
| SRP007169 | FBXO6 | 26270 | RNAseq | -0.6964 | 0.0977 | |
| SRP008496 | FBXO6 | 26270 | RNAseq | -0.2300 | 0.4728 | |
| SRP064894 | FBXO6 | 26270 | RNAseq | 0.5886 | 0.0189 | |
| SRP133303 | FBXO6 | 26270 | RNAseq | 0.6195 | 0.0468 | |
| SRP159526 | FBXO6 | 26270 | RNAseq | -0.0664 | 0.8622 | |
| SRP193095 | FBXO6 | 26270 | RNAseq | 0.1999 | 0.1504 | |
| SRP219564 | FBXO6 | 26270 | RNAseq | 0.5453 | 0.1439 | |
| TCGA | FBXO6 | 26270 | RNAseq | 0.3135 | 0.0009 |
Upregulated datasets: 1; Downregulated datasets: 0.
Survival by FBXO6 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of FBXO6:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | FBXO6 | 26270 | 0 | 5 | 25 | |
| GSE20123 | FBXO6 | 26270 | 0 | 4 | 26 | |
| GSE43470 | FBXO6 | 26270 | 5 | 5 | 33 | |
| GSE46452 | FBXO6 | 26270 | 7 | 1 | 51 | |
| GSE47630 | FBXO6 | 26270 | 8 | 4 | 28 | |
| GSE54993 | FBXO6 | 26270 | 3 | 1 | 66 | |
| GSE54994 | FBXO6 | 26270 | 11 | 4 | 38 | |
| GSE60625 | FBXO6 | 26270 | 0 | 0 | 11 | |
| GSE74703 | FBXO6 | 26270 | 4 | 3 | 29 | |
| GSE74704 | FBXO6 | 26270 | 0 | 0 | 20 | |
| TCGA | FBXO6 | 26270 | 10 | 23 | 63 |
Total number of gains: 48; Total number of losses: 50; Total Number of normals: 390.
Somatic mutations of FBXO6:
Generating mutation plots.
Highly correlated genes for FBXO6:
Showing top 20/312 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| FBXO6 | SCO2 | 0.759185 | 3 | 0 | 3 |
| FBXO6 | ATAT1 | 0.754685 | 3 | 0 | 3 |
| FBXO6 | ZNF789 | 0.743329 | 3 | 0 | 3 |
| FBXO6 | RFX5 | 0.739993 | 3 | 0 | 3 |
| FBXO6 | PRKCSH | 0.734801 | 3 | 0 | 3 |
| FBXO6 | LILRB1 | 0.734079 | 3 | 0 | 3 |
| FBXO6 | AGPAT3 | 0.732474 | 3 | 0 | 3 |
| FBXO6 | STAT2 | 0.719047 | 4 | 0 | 3 |
| FBXO6 | TAPBP | 0.715752 | 6 | 0 | 6 |
| FBXO6 | PARP9 | 0.715172 | 7 | 0 | 7 |
| FBXO6 | PSMB8 | 0.712166 | 7 | 0 | 6 |
| FBXO6 | TRIM21 | 0.710998 | 6 | 0 | 6 |
| FBXO6 | BRPF3 | 0.709821 | 3 | 0 | 3 |
| FBXO6 | SKI | 0.70555 | 3 | 0 | 3 |
| FBXO6 | ZNF578 | 0.700575 | 3 | 0 | 3 |
| FBXO6 | BIN2 | 0.694746 | 3 | 0 | 3 |
| FBXO6 | LINC00623 | 0.686629 | 3 | 0 | 3 |
| FBXO6 | MON1A | 0.685883 | 3 | 0 | 3 |
| FBXO6 | SLC29A3 | 0.685085 | 5 | 0 | 4 |
| FBXO6 | XAF1 | 0.683972 | 6 | 0 | 5 |
For details and further investigation, click here
