| Full name: chromosome 14 open reading frame 180 | Alias Symbol: NRAC | ||
| Type: protein-coding gene | Cytoband: 14q32.33 | ||
| Entrez ID: 400258 | HGNC ID: HGNC:33795 | Ensembl Gene: ENSG00000184601 | OMIM ID: |
| Drug and gene relationship at DGIdb | |||
Expression of C14orf180:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | C14orf180 | 400258 | 1558420_at | -0.0022 | 0.9951 | |
| GSE26886 | C14orf180 | 400258 | 1558420_at | -0.1229 | 0.3868 | |
| GSE45670 | C14orf180 | 400258 | 1558420_at | 0.0245 | 0.8257 | |
| GSE53622 | C14orf180 | 400258 | 45572 | -1.6687 | 0.0000 | |
| GSE53624 | C14orf180 | 400258 | 45572 | -1.3518 | 0.0000 | |
| GSE63941 | C14orf180 | 400258 | 1558420_at | -0.2100 | 0.2354 | |
| GSE77861 | C14orf180 | 400258 | 1558420_at | -0.2310 | 0.0735 | |
| GSE97050 | C14orf180 | 400258 | A_33_P3355708 | 0.0017 | 0.9971 | |
| TCGA | C14orf180 | 400258 | RNAseq | -5.8398 | 0.0035 |
Upregulated datasets: 0; Downregulated datasets: 3.
Survival by C14orf180 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of C14orf180:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | C14orf180 | 400258 | 11 | 3 | 16 | |
| GSE20123 | C14orf180 | 400258 | 10 | 2 | 18 | |
| GSE43470 | C14orf180 | 400258 | 6 | 4 | 33 | |
| GSE46452 | C14orf180 | 400258 | 19 | 4 | 36 | |
| GSE47630 | C14orf180 | 400258 | 10 | 8 | 22 | |
| GSE54993 | C14orf180 | 400258 | 4 | 10 | 56 | |
| GSE54994 | C14orf180 | 400258 | 21 | 4 | 28 | |
| GSE60625 | C14orf180 | 400258 | 0 | 2 | 9 | |
| GSE74703 | C14orf180 | 400258 | 5 | 3 | 28 | |
| GSE74704 | C14orf180 | 400258 | 5 | 2 | 13 | |
| TCGA | C14orf180 | 400258 | 32 | 19 | 45 |
Total number of gains: 123; Total number of losses: 61; Total Number of normals: 304.
Somatic mutations of C14orf180:
Generating mutation plots.
Highly correlated genes for C14orf180:
Showing top 20/427 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| C14orf180 | OR10G8 | 0.829806 | 3 | 0 | 3 |
| C14orf180 | KRTAP20-1 | 0.828298 | 3 | 0 | 3 |
| C14orf180 | MFSD2B | 0.826167 | 3 | 0 | 3 |
| C14orf180 | OR10G3 | 0.807281 | 3 | 0 | 3 |
| C14orf180 | COX4I2 | 0.795233 | 3 | 0 | 3 |
| C14orf180 | FAM71E2 | 0.792229 | 3 | 0 | 3 |
| C14orf180 | CLDN24 | 0.787422 | 3 | 0 | 3 |
| C14orf180 | FAM163B | 0.780179 | 3 | 0 | 3 |
| C14orf180 | C11orf21 | 0.770457 | 3 | 0 | 3 |
| C14orf180 | MARCO | 0.769021 | 3 | 0 | 3 |
| C14orf180 | DEGS2 | 0.766807 | 4 | 0 | 4 |
| C14orf180 | SLC25A47 | 0.760182 | 3 | 0 | 3 |
| C14orf180 | FFAR1 | 0.759693 | 3 | 0 | 3 |
| C14orf180 | BARHL2 | 0.759277 | 3 | 0 | 3 |
| C14orf180 | IL9R | 0.757551 | 3 | 0 | 3 |
| C14orf180 | GRM4 | 0.754208 | 3 | 0 | 3 |
| C14orf180 | OR2Z1 | 0.7527 | 4 | 0 | 3 |
| C14orf180 | HMGB4 | 0.749461 | 3 | 0 | 3 |
| C14orf180 | EGFLAM-AS2 | 0.746946 | 3 | 0 | 3 |
| C14orf180 | TEN1 | 0.746257 | 3 | 0 | 3 |
For details and further investigation, click here
