| Full name: macrophage receptor with collagenous structure | Alias Symbol: SCARA2|SR-A6 | ||
| Type: protein-coding gene | Cytoband: 2q14.2 | ||
| Entrez ID: 8685 | HGNC ID: HGNC:6895 | Ensembl Gene: ENSG00000019169 | OMIM ID: 604870 |
| Drug and gene relationship at DGIdb | |||
Expression of MARCO:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | MARCO | 8685 | 205819_at | 0.1891 | 0.7523 | |
| GSE20347 | MARCO | 8685 | 205819_at | -0.1412 | 0.0434 | |
| GSE23400 | MARCO | 8685 | 205819_at | 0.0310 | 0.7533 | |
| GSE26886 | MARCO | 8685 | 205819_at | -0.1982 | 0.5874 | |
| GSE29001 | MARCO | 8685 | 205819_at | -0.0710 | 0.8775 | |
| GSE38129 | MARCO | 8685 | 205819_at | -0.1902 | 0.0703 | |
| GSE45670 | MARCO | 8685 | 205819_at | -0.0791 | 0.6662 | |
| GSE53622 | MARCO | 8685 | 5454 | 0.0345 | 0.8488 | |
| GSE53624 | MARCO | 8685 | 5454 | -0.1192 | 0.4449 | |
| GSE63941 | MARCO | 8685 | 205819_at | 0.0088 | 0.9674 | |
| GSE77861 | MARCO | 8685 | 205819_at | -0.1556 | 0.3769 | |
| GSE97050 | MARCO | 8685 | A_23_P101992 | 0.4450 | 0.4458 | |
| SRP064894 | MARCO | 8685 | RNAseq | 1.1222 | 0.0518 | |
| SRP133303 | MARCO | 8685 | RNAseq | 0.6267 | 0.0768 | |
| SRP159526 | MARCO | 8685 | RNAseq | -0.9234 | 0.2084 | |
| TCGA | MARCO | 8685 | RNAseq | 0.0140 | 0.9777 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by MARCO expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of MARCO:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | MARCO | 8685 | 5 | 1 | 24 | |
| GSE20123 | MARCO | 8685 | 5 | 1 | 24 | |
| GSE43470 | MARCO | 8685 | 3 | 1 | 39 | |
| GSE46452 | MARCO | 8685 | 1 | 4 | 54 | |
| GSE47630 | MARCO | 8685 | 6 | 0 | 34 | |
| GSE54993 | MARCO | 8685 | 0 | 6 | 64 | |
| GSE54994 | MARCO | 8685 | 12 | 0 | 41 | |
| GSE60625 | MARCO | 8685 | 0 | 3 | 8 | |
| GSE74703 | MARCO | 8685 | 3 | 1 | 32 | |
| GSE74704 | MARCO | 8685 | 3 | 1 | 16 | |
| TCGA | MARCO | 8685 | 32 | 6 | 58 |
Total number of gains: 70; Total number of losses: 24; Total Number of normals: 394.
Somatic mutations of MARCO:
Generating mutation plots.
Highly correlated genes for MARCO:
Showing top 20/58 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| MARCO | CABP2 | 0.783672 | 3 | 0 | 3 |
| MARCO | C14orf180 | 0.769021 | 3 | 0 | 3 |
| MARCO | ROM1 | 0.723143 | 3 | 0 | 3 |
| MARCO | GZMM | 0.709654 | 3 | 0 | 3 |
| MARCO | ATAD3C | 0.698187 | 3 | 0 | 3 |
| MARCO | SLC6A18 | 0.697945 | 3 | 0 | 3 |
| MARCO | FAM207A | 0.697099 | 3 | 0 | 3 |
| MARCO | GPN2 | 0.676891 | 3 | 0 | 3 |
| MARCO | SLC35F3 | 0.672652 | 3 | 0 | 3 |
| MARCO | ADAMTS7 | 0.669907 | 4 | 0 | 3 |
| MARCO | SLC22A13 | 0.663981 | 4 | 0 | 3 |
| MARCO | MUC8 | 0.662921 | 3 | 0 | 3 |
| MARCO | DND1 | 0.653544 | 3 | 0 | 3 |
| MARCO | IGFALS | 0.646793 | 3 | 0 | 3 |
| MARCO | TTC1 | 0.645601 | 3 | 0 | 3 |
| MARCO | CLEC1B | 0.644894 | 3 | 0 | 3 |
| MARCO | MAGEA8 | 0.637736 | 4 | 0 | 3 |
| MARCO | PLEKHN1 | 0.636078 | 4 | 0 | 3 |
| MARCO | BCL2L10 | 0.635936 | 3 | 0 | 3 |
| MARCO | IL23A | 0.635793 | 3 | 0 | 3 |
For details and further investigation, click here
