| Full name: chromosome 11 open reading frame 21 | Alias Symbol: | ||
| Type: protein-coding gene | Cytoband: 11p15.5 | ||
| Entrez ID: 29125 | HGNC ID: HGNC:13231 | Ensembl Gene: ENSG00000110665 | OMIM ID: 611033 |
| Drug and gene relationship at DGIdb | |||
Expression of C11orf21:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | C11orf21 | 29125 | 220560_at | -0.2753 | 0.4701 | |
| GSE20347 | C11orf21 | 29125 | 220560_at | -0.0083 | 0.9405 | |
| GSE23400 | C11orf21 | 29125 | 220560_at | -0.0967 | 0.0109 | |
| GSE26886 | C11orf21 | 29125 | 1568978_s_at | -0.2218 | 0.1495 | |
| GSE29001 | C11orf21 | 29125 | 220560_at | -0.2274 | 0.0711 | |
| GSE38129 | C11orf21 | 29125 | 220560_at | -0.2447 | 0.0116 | |
| GSE45670 | C11orf21 | 29125 | 1568978_s_at | 0.0028 | 0.9872 | |
| GSE53622 | C11orf21 | 29125 | 4366 | -0.0089 | 0.9146 | |
| GSE53624 | C11orf21 | 29125 | 4366 | 0.2614 | 0.0004 | |
| GSE63941 | C11orf21 | 29125 | 1568978_s_at | 0.0272 | 0.8792 | |
| GSE77861 | C11orf21 | 29125 | 1568978_s_at | -0.1728 | 0.1058 | |
| GSE97050 | C11orf21 | 29125 | A_33_P3377229 | -0.0560 | 0.8162 | |
| SRP064894 | C11orf21 | 29125 | RNAseq | -0.4052 | 0.2963 | |
| SRP133303 | C11orf21 | 29125 | RNAseq | -0.8655 | 0.0026 | |
| SRP159526 | C11orf21 | 29125 | RNAseq | -1.1663 | 0.1306 | |
| SRP219564 | C11orf21 | 29125 | RNAseq | 0.0117 | 0.9821 | |
| TCGA | C11orf21 | 29125 | RNAseq | -1.4299 | 0.0012 |
Upregulated datasets: 0; Downregulated datasets: 1.
Survival by C11orf21 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of C11orf21:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | C11orf21 | 29125 | 1 | 11 | 18 | |
| GSE20123 | C11orf21 | 29125 | 1 | 12 | 17 | |
| GSE43470 | C11orf21 | 29125 | 1 | 9 | 33 | |
| GSE46452 | C11orf21 | 29125 | 7 | 8 | 44 | |
| GSE47630 | C11orf21 | 29125 | 4 | 12 | 24 | |
| GSE54993 | C11orf21 | 29125 | 3 | 1 | 66 | |
| GSE54994 | C11orf21 | 29125 | 1 | 12 | 40 | |
| GSE60625 | C11orf21 | 29125 | 0 | 0 | 11 | |
| GSE74703 | C11orf21 | 29125 | 1 | 7 | 28 | |
| GSE74704 | C11orf21 | 29125 | 0 | 8 | 12 | |
| TCGA | C11orf21 | 29125 | 8 | 39 | 49 |
Total number of gains: 27; Total number of losses: 119; Total Number of normals: 342.
Somatic mutations of C11orf21:
Generating mutation plots.
Highly correlated genes for C11orf21:
Showing top 20/453 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| C11orf21 | C1QL2 | 0.780892 | 3 | 0 | 3 |
| C11orf21 | MAFA | 0.780295 | 3 | 0 | 3 |
| C11orf21 | C14orf180 | 0.770457 | 3 | 0 | 3 |
| C11orf21 | MCF2L | 0.764036 | 3 | 0 | 3 |
| C11orf21 | FFAR1 | 0.749059 | 4 | 0 | 4 |
| C11orf21 | PPM1N | 0.733946 | 3 | 0 | 3 |
| C11orf21 | PHGR1 | 0.732735 | 3 | 0 | 3 |
| C11orf21 | RGL4 | 0.732177 | 3 | 0 | 3 |
| C11orf21 | TSPAN11 | 0.731318 | 4 | 0 | 3 |
| C11orf21 | IQCF3 | 0.718519 | 3 | 0 | 3 |
| C11orf21 | PHOSPHO1 | 0.71468 | 3 | 0 | 3 |
| C11orf21 | LHB | 0.711843 | 3 | 0 | 3 |
| C11orf21 | TNN | 0.709728 | 3 | 0 | 3 |
| C11orf21 | OR1J1 | 0.708835 | 3 | 0 | 3 |
| C11orf21 | ANKRD33B | 0.702141 | 4 | 0 | 4 |
| C11orf21 | SHISA8 | 0.695432 | 4 | 0 | 4 |
| C11orf21 | IGFN1 | 0.69438 | 3 | 0 | 3 |
| C11orf21 | SPEF2 | 0.693995 | 3 | 0 | 3 |
| C11orf21 | ZGLP1 | 0.690763 | 4 | 0 | 3 |
| C11orf21 | SPNS3 | 0.689198 | 4 | 0 | 4 |
For details and further investigation, click here
