| Full name: cytochrome c oxidase subunit 4I2 | Alias Symbol: COXIV-2|COX4B|dJ857M17.2|COX4-2 | ||
| Type: protein-coding gene | Cytoband: 20q11.21 | ||
| Entrez ID: 84701 | HGNC ID: HGNC:16232 | Ensembl Gene: ENSG00000131055 | OMIM ID: 607976 |
| Drug and gene relationship at DGIdb | |||
Expression of COX4I2:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | COX4I2 | 84701 | 232761_at | -0.0849 | 0.8312 | |
| GSE26886 | COX4I2 | 84701 | 232761_at | 0.0559 | 0.6508 | |
| GSE45670 | COX4I2 | 84701 | 232761_at | 0.0136 | 0.8944 | |
| GSE63941 | COX4I2 | 84701 | 232761_at | 0.0053 | 0.9820 | |
| GSE77861 | COX4I2 | 84701 | 232761_at | -0.1600 | 0.0945 | |
| GSE97050 | COX4I2 | 84701 | A_23_P210869 | 0.0118 | 0.9773 | |
| SRP064894 | COX4I2 | 84701 | RNAseq | -0.1954 | 0.6521 | |
| SRP133303 | COX4I2 | 84701 | RNAseq | -1.0629 | 0.0002 | |
| SRP159526 | COX4I2 | 84701 | RNAseq | -0.3192 | 0.5754 | |
| SRP219564 | COX4I2 | 84701 | RNAseq | -0.5022 | 0.2283 | |
| TCGA | COX4I2 | 84701 | RNAseq | 0.0770 | 0.7433 |
Upregulated datasets: 0; Downregulated datasets: 1.
Survival by COX4I2 expression:
 |
| TCGA |
Note: Click image to view full size file.
Copy number change of COX4I2:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | COX4I2 | 84701 | 14 | 0 | 16 | |
| GSE20123 | COX4I2 | 84701 | 14 | 0 | 16 | |
| GSE43470 | COX4I2 | 84701 | 11 | 0 | 32 | |
| GSE46452 | COX4I2 | 84701 | 29 | 0 | 30 | |
| GSE47630 | COX4I2 | 84701 | 24 | 0 | 16 | |
| GSE54993 | COX4I2 | 84701 | 0 | 17 | 53 | |
| GSE54994 | COX4I2 | 84701 | 27 | 1 | 25 | |
| GSE60625 | COX4I2 | 84701 | 0 | 0 | 11 | |
| GSE74703 | COX4I2 | 84701 | 10 | 0 | 26 | |
| GSE74704 | COX4I2 | 84701 | 9 | 0 | 11 | |
| TCGA | COX4I2 | 84701 | 49 | 1 | 46 |
Total number of gains: 187; Total number of losses: 19; Total Number of normals: 282.
Somatic mutations of COX4I2:
Generating mutation plots.
Highly correlated genes for COX4I2:
Showing top 20/75 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| COX4I2 | C14orf180 | 0.795233 | 3 | 0 | 3 |
| COX4I2 | RGL4 | 0.744981 | 3 | 0 | 3 |
| COX4I2 | CD300LG | 0.743089 | 3 | 0 | 3 |
| COX4I2 | MYO1A | 0.74286 | 3 | 0 | 3 |
| COX4I2 | SCARF2 | 0.733161 | 3 | 0 | 3 |
| COX4I2 | ADAMTS7 | 0.717038 | 3 | 0 | 3 |
| COX4I2 | C22orf23 | 0.712564 | 3 | 0 | 3 |
| COX4I2 | WFIKKN2 | 0.712108 | 3 | 0 | 3 |
| COX4I2 | HAAO | 0.708897 | 3 | 0 | 3 |
| COX4I2 | ITIH3 | 0.705931 | 4 | 0 | 3 |
| COX4I2 | SVOPL | 0.705822 | 3 | 0 | 3 |
| COX4I2 | NTRK1 | 0.699876 | 3 | 0 | 3 |
| COX4I2 | SIRPD | 0.699051 | 3 | 0 | 3 |
| COX4I2 | OPRD1 | 0.695282 | 3 | 0 | 3 |
| COX4I2 | INSL3 | 0.692889 | 3 | 0 | 3 |
| COX4I2 | PGLYRP1 | 0.690515 | 3 | 0 | 3 |
| COX4I2 | C1QTNF6 | 0.689612 | 3 | 0 | 3 |
| COX4I2 | CABP7 | 0.689231 | 3 | 0 | 3 |
| COX4I2 | SUN2 | 0.687971 | 3 | 0 | 3 |
| COX4I2 | CA4 | 0.686646 | 3 | 0 | 3 |
For details and further investigation, click here
