| Full name: chromosome 3 open reading frame 18 | Alias Symbol: G20 | ||
| Type: protein-coding gene | Cytoband: 3p21.31 | ||
| Entrez ID: 51161 | HGNC ID: HGNC:24837 | Ensembl Gene: ENSG00000088543 | OMIM ID: |
| Drug and gene relationship at DGIdb | |||
Expression of C3orf18:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | C3orf18 | 51161 | 219114_at | -0.1732 | 0.7319 | |
| GSE20347 | C3orf18 | 51161 | 219114_at | -0.0321 | 0.6615 | |
| GSE23400 | C3orf18 | 51161 | 219114_at | -0.1403 | 0.0015 | |
| GSE26886 | C3orf18 | 51161 | 219114_at | 0.1010 | 0.4931 | |
| GSE29001 | C3orf18 | 51161 | 219114_at | -0.1308 | 0.5441 | |
| GSE38129 | C3orf18 | 51161 | 219114_at | -0.3896 | 0.0037 | |
| GSE45670 | C3orf18 | 51161 | 219114_at | -0.4873 | 0.0000 | |
| GSE53622 | C3orf18 | 51161 | 100343 | -0.9164 | 0.0000 | |
| GSE53624 | C3orf18 | 51161 | 100343 | -0.5716 | 0.0000 | |
| GSE63941 | C3orf18 | 51161 | 219114_at | -1.2214 | 0.0016 | |
| GSE77861 | C3orf18 | 51161 | 219114_at | -0.0112 | 0.9526 | |
| GSE97050 | C3orf18 | 51161 | A_23_P155477 | -1.1696 | 0.0750 | |
| SRP064894 | C3orf18 | 51161 | RNAseq | 0.0369 | 0.9163 | |
| SRP133303 | C3orf18 | 51161 | RNAseq | -0.4568 | 0.1879 | |
| SRP159526 | C3orf18 | 51161 | RNAseq | -0.5364 | 0.0716 | |
| SRP193095 | C3orf18 | 51161 | RNAseq | 0.1893 | 0.4611 | |
| SRP219564 | C3orf18 | 51161 | RNAseq | -0.5810 | 0.4778 | |
| TCGA | C3orf18 | 51161 | RNAseq | -1.1845 | 0.0000 |
Upregulated datasets: 0; Downregulated datasets: 2.
Survival by C3orf18 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of C3orf18:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | C3orf18 | 51161 | 0 | 18 | 12 | |
| GSE20123 | C3orf18 | 51161 | 0 | 19 | 11 | |
| GSE43470 | C3orf18 | 51161 | 0 | 19 | 24 | |
| GSE46452 | C3orf18 | 51161 | 2 | 16 | 41 | |
| GSE47630 | C3orf18 | 51161 | 1 | 24 | 15 | |
| GSE54993 | C3orf18 | 51161 | 6 | 2 | 62 | |
| GSE54994 | C3orf18 | 51161 | 0 | 34 | 19 | |
| GSE60625 | C3orf18 | 51161 | 5 | 0 | 6 | |
| GSE74703 | C3orf18 | 51161 | 0 | 15 | 21 | |
| GSE74704 | C3orf18 | 51161 | 0 | 12 | 8 | |
| TCGA | C3orf18 | 51161 | 0 | 78 | 18 |
Total number of gains: 14; Total number of losses: 237; Total Number of normals: 237.
Somatic mutations of C3orf18:
Generating mutation plots.
Highly correlated genes for C3orf18:
Showing top 20/1215 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| C3orf18 | C20orf194 | 0.810177 | 3 | 0 | 3 |
| C3orf18 | RBM24 | 0.779261 | 5 | 0 | 5 |
| C3orf18 | DNAJC18 | 0.778164 | 3 | 0 | 3 |
| C3orf18 | SORCS1 | 0.775704 | 4 | 0 | 4 |
| C3orf18 | COPZ2 | 0.766028 | 4 | 0 | 4 |
| C3orf18 | CLEC3B | 0.763959 | 3 | 0 | 3 |
| C3orf18 | LSM11 | 0.760681 | 4 | 0 | 4 |
| C3orf18 | CYS1 | 0.754382 | 7 | 0 | 7 |
| C3orf18 | ADAMTS5 | 0.753568 | 8 | 0 | 8 |
| C3orf18 | SMIM10 | 0.751118 | 5 | 0 | 5 |
| C3orf18 | C1QTNF7 | 0.746573 | 5 | 0 | 5 |
| C3orf18 | TNFSF12 | 0.746192 | 4 | 0 | 3 |
| C3orf18 | MIR100HG | 0.746107 | 5 | 0 | 5 |
| C3orf18 | ANO5 | 0.745434 | 6 | 0 | 6 |
| C3orf18 | NEGR1 | 0.738641 | 6 | 0 | 6 |
| C3orf18 | CYP2U1 | 0.738364 | 6 | 0 | 5 |
| C3orf18 | LIX1L | 0.736822 | 6 | 0 | 6 |
| C3orf18 | CORO6 | 0.736335 | 3 | 0 | 3 |
| C3orf18 | NACC2 | 0.734424 | 7 | 0 | 7 |
| C3orf18 | LRCH2 | 0.734009 | 6 | 0 | 5 |
For details and further investigation, click here
