| Full name: LSM11, U7 small nuclear RNA associated | Alias Symbol: FLJ38273 | ||
| Type: protein-coding gene | Cytoband: 5q33.3 | ||
| Entrez ID: 134353 | HGNC ID: HGNC:30860 | Ensembl Gene: ENSG00000155858 | OMIM ID: 617910 |
| Drug and gene relationship at DGIdb | |||
Screen Evidence:
| |||
Expression of LSM11:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | LSM11 | 134353 | 226826_at | -0.9535 | 0.4598 | |
| GSE26886 | LSM11 | 134353 | 226826_at | 0.0933 | 0.8099 | |
| GSE45670 | LSM11 | 134353 | 226826_at | -0.5053 | 0.0128 | |
| GSE53622 | LSM11 | 134353 | 41034 | -0.2620 | 0.0364 | |
| GSE53624 | LSM11 | 134353 | 41034 | 0.1656 | 0.0291 | |
| GSE63941 | LSM11 | 134353 | 226826_at | -0.0281 | 0.9693 | |
| GSE77861 | LSM11 | 134353 | 226819_at | -0.2153 | 0.0453 | |
| GSE97050 | LSM11 | 134353 | A_23_P368195 | -0.2113 | 0.5714 | |
| SRP007169 | LSM11 | 134353 | RNAseq | 0.0588 | 0.8806 | |
| SRP008496 | LSM11 | 134353 | RNAseq | 0.2050 | 0.4498 | |
| SRP064894 | LSM11 | 134353 | RNAseq | 0.1911 | 0.2863 | |
| SRP133303 | LSM11 | 134353 | RNAseq | 0.3851 | 0.1241 | |
| SRP159526 | LSM11 | 134353 | RNAseq | -0.5141 | 0.0835 | |
| SRP193095 | LSM11 | 134353 | RNAseq | -0.0862 | 0.2511 | |
| SRP219564 | LSM11 | 134353 | RNAseq | 0.0479 | 0.9401 | |
| TCGA | LSM11 | 134353 | RNAseq | -0.2185 | 0.0022 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by LSM11 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of LSM11:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | LSM11 | 134353 | 0 | 11 | 19 | |
| GSE20123 | LSM11 | 134353 | 0 | 11 | 19 | |
| GSE43470 | LSM11 | 134353 | 2 | 11 | 30 | |
| GSE46452 | LSM11 | 134353 | 0 | 27 | 32 | |
| GSE47630 | LSM11 | 134353 | 0 | 20 | 20 | |
| GSE54993 | LSM11 | 134353 | 9 | 1 | 60 | |
| GSE54994 | LSM11 | 134353 | 1 | 16 | 36 | |
| GSE60625 | LSM11 | 134353 | 0 | 0 | 11 | |
| GSE74703 | LSM11 | 134353 | 2 | 8 | 26 | |
| GSE74704 | LSM11 | 134353 | 0 | 6 | 14 | |
| TCGA | LSM11 | 134353 | 5 | 36 | 55 |
Total number of gains: 19; Total number of losses: 147; Total Number of normals: 322.
Somatic mutations of LSM11:
Generating mutation plots.
Highly correlated genes for LSM11:
Showing top 20/605 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| LSM11 | FAM83D | 0.849356 | 3 | 0 | 3 |
| LSM11 | NDUFA8 | 0.813177 | 3 | 0 | 3 |
| LSM11 | RBM18 | 0.81256 | 3 | 0 | 3 |
| LSM11 | HABP4 | 0.804259 | 3 | 0 | 3 |
| LSM11 | FUNDC2 | 0.797964 | 3 | 0 | 3 |
| LSM11 | RSRC2 | 0.789523 | 3 | 0 | 3 |
| LSM11 | NKAPL | 0.788348 | 3 | 0 | 3 |
| LSM11 | WBP4 | 0.785439 | 4 | 0 | 4 |
| LSM11 | TRAK1 | 0.782518 | 3 | 0 | 3 |
| LSM11 | CTR9 | 0.778072 | 3 | 0 | 3 |
| LSM11 | RASL12 | 0.777579 | 4 | 0 | 4 |
| LSM11 | CBLL1 | 0.77664 | 3 | 0 | 3 |
| LSM11 | TLN1 | 0.774867 | 3 | 0 | 3 |
| LSM11 | ZNF79 | 0.772612 | 3 | 0 | 3 |
| LSM11 | JPH2 | 0.769004 | 4 | 0 | 4 |
| LSM11 | CDAN1 | 0.760783 | 3 | 0 | 3 |
| LSM11 | C3orf18 | 0.760681 | 4 | 0 | 4 |
| LSM11 | BEX4 | 0.757462 | 3 | 0 | 3 |
| LSM11 | NACC2 | 0.75226 | 5 | 0 | 5 |
| LSM11 | ALPK3 | 0.750536 | 4 | 0 | 4 |
For details and further investigation, click here
