| Full name: coatomer protein complex subunit zeta 2 | Alias Symbol: MGC23008 | ||
| Type: protein-coding gene | Cytoband: 17q21.32 | ||
| Entrez ID: 51226 | HGNC ID: HGNC:19356 | Ensembl Gene: ENSG00000005243 | OMIM ID: 615526 |
| Drug and gene relationship at DGIdb | |||
Expression of COPZ2:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | COPZ2 | 51226 | 219561_at | -0.1423 | 0.8901 | |
| GSE20347 | COPZ2 | 51226 | 219561_at | 0.3876 | 0.0561 | |
| GSE23400 | COPZ2 | 51226 | 219561_at | 0.1211 | 0.1170 | |
| GSE26886 | COPZ2 | 51226 | 219561_at | 0.9090 | 0.0000 | |
| GSE29001 | COPZ2 | 51226 | 219561_at | 1.0240 | 0.0051 | |
| GSE38129 | COPZ2 | 51226 | 219561_at | 0.0873 | 0.7745 | |
| GSE45670 | COPZ2 | 51226 | 219561_at | 0.1926 | 0.5479 | |
| GSE53622 | COPZ2 | 51226 | 622 | 0.9741 | 0.0000 | |
| GSE53624 | COPZ2 | 51226 | 622 | 1.2852 | 0.0000 | |
| GSE63941 | COPZ2 | 51226 | 219561_at | -3.1681 | 0.0078 | |
| GSE77861 | COPZ2 | 51226 | 219561_at | 0.8242 | 0.0143 | |
| GSE97050 | COPZ2 | 51226 | A_23_P101093 | -0.3728 | 0.4105 | |
| SRP007169 | COPZ2 | 51226 | RNAseq | 2.2512 | 0.0000 | |
| SRP008496 | COPZ2 | 51226 | RNAseq | 2.5772 | 0.0000 | |
| SRP064894 | COPZ2 | 51226 | RNAseq | 1.5668 | 0.0003 | |
| SRP133303 | COPZ2 | 51226 | RNAseq | 1.4422 | 0.0000 | |
| SRP159526 | COPZ2 | 51226 | RNAseq | 0.8474 | 0.0183 | |
| SRP193095 | COPZ2 | 51226 | RNAseq | 2.0150 | 0.0000 | |
| SRP219564 | COPZ2 | 51226 | RNAseq | 0.2950 | 0.7136 | |
| TCGA | COPZ2 | 51226 | RNAseq | 0.3595 | 0.0154 |
Upregulated datasets: 7; Downregulated datasets: 1.
Survival by COPZ2 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of COPZ2:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | COPZ2 | 51226 | 5 | 2 | 23 | |
| GSE20123 | COPZ2 | 51226 | 5 | 2 | 23 | |
| GSE43470 | COPZ2 | 51226 | 1 | 2 | 40 | |
| GSE46452 | COPZ2 | 51226 | 32 | 0 | 27 | |
| GSE47630 | COPZ2 | 51226 | 9 | 0 | 31 | |
| GSE54993 | COPZ2 | 51226 | 2 | 4 | 64 | |
| GSE54994 | COPZ2 | 51226 | 11 | 5 | 37 | |
| GSE60625 | COPZ2 | 51226 | 4 | 0 | 7 | |
| GSE74703 | COPZ2 | 51226 | 1 | 1 | 34 | |
| GSE74704 | COPZ2 | 51226 | 4 | 1 | 15 | |
| TCGA | COPZ2 | 51226 | 27 | 6 | 63 |
Total number of gains: 101; Total number of losses: 23; Total Number of normals: 364.
Somatic mutations of COPZ2:
Generating mutation plots.
Highly correlated genes for COPZ2:
Showing top 20/1283 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| COPZ2 | TCEA2 | 0.778751 | 4 | 0 | 4 |
| COPZ2 | C3orf18 | 0.766028 | 4 | 0 | 4 |
| COPZ2 | MRGPRF | 0.763899 | 4 | 0 | 4 |
| COPZ2 | JMY | 0.758556 | 3 | 0 | 3 |
| COPZ2 | CC2D2A | 0.754303 | 3 | 0 | 3 |
| COPZ2 | CLMP | 0.747608 | 5 | 0 | 5 |
| COPZ2 | HINT1 | 0.739666 | 3 | 0 | 3 |
| COPZ2 | MRVI1 | 0.737832 | 3 | 0 | 3 |
| COPZ2 | MMRN2 | 0.73447 | 3 | 0 | 3 |
| COPZ2 | ASB2 | 0.732831 | 3 | 0 | 3 |
| COPZ2 | RNF14 | 0.731296 | 3 | 0 | 3 |
| COPZ2 | DNAJC18 | 0.721469 | 4 | 0 | 3 |
| COPZ2 | FZD4 | 0.71779 | 3 | 0 | 3 |
| COPZ2 | PTGFRN | 0.717718 | 6 | 0 | 6 |
| COPZ2 | TMTC1 | 0.717576 | 5 | 0 | 5 |
| COPZ2 | LINC00888 | 0.715219 | 3 | 0 | 3 |
| COPZ2 | MAN1C1 | 0.713318 | 3 | 0 | 3 |
| COPZ2 | ANKS3 | 0.712215 | 3 | 0 | 3 |
| COPZ2 | TCF21 | 0.712212 | 3 | 0 | 3 |
| COPZ2 | MAP1B | 0.711103 | 7 | 0 | 6 |
For details and further investigation, click here
