| Full name: calcium homeostasis modulator 1 | Alias Symbol: | ||
| Type: protein-coding gene | Cytoband: 10q24.33 | ||
| Entrez ID: 255022 | HGNC ID: HGNC:23494 | Ensembl Gene: ENSG00000185933 | OMIM ID: 612234 |
| Drug and gene relationship at DGIdb | |||
CALHM1 involved pathways:
| KEGG pathway | Description | View |
|---|---|---|
| hsa04742 | Taste transduction |
Expression of CALHM1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | CALHM1 | 255022 | 1554367_at | -0.0237 | 0.9438 | |
| GSE26886 | CALHM1 | 255022 | 1554367_at | 0.0402 | 0.7637 | |
| GSE45670 | CALHM1 | 255022 | 1554367_at | 0.1358 | 0.1809 | |
| GSE53622 | CALHM1 | 255022 | 67674 | 0.3637 | 0.0030 | |
| GSE53624 | CALHM1 | 255022 | 67674 | 0.3759 | 0.0064 | |
| GSE63941 | CALHM1 | 255022 | 1554367_at | 0.0575 | 0.7339 | |
| GSE77861 | CALHM1 | 255022 | 1554367_at | 0.0199 | 0.8728 | |
| SRP133303 | CALHM1 | 255022 | RNAseq | 0.4077 | 0.1840 | |
| TCGA | CALHM1 | 255022 | RNAseq | 0.9014 | 0.2348 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by CALHM1 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of CALHM1:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | CALHM1 | 255022 | 2 | 9 | 19 | |
| GSE20123 | CALHM1 | 255022 | 2 | 8 | 20 | |
| GSE43470 | CALHM1 | 255022 | 0 | 8 | 35 | |
| GSE46452 | CALHM1 | 255022 | 0 | 11 | 48 | |
| GSE47630 | CALHM1 | 255022 | 2 | 14 | 24 | |
| GSE54993 | CALHM1 | 255022 | 8 | 0 | 62 | |
| GSE54994 | CALHM1 | 255022 | 1 | 10 | 42 | |
| GSE60625 | CALHM1 | 255022 | 0 | 0 | 11 | |
| GSE74703 | CALHM1 | 255022 | 0 | 5 | 31 | |
| GSE74704 | CALHM1 | 255022 | 1 | 4 | 15 | |
| TCGA | CALHM1 | 255022 | 6 | 28 | 62 |
Total number of gains: 22; Total number of losses: 97; Total Number of normals: 369.
Somatic mutations of CALHM1:
Generating mutation plots.
Highly correlated genes for CALHM1:
Showing top 20/21 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| CALHM1 | NOS1 | 0.68371 | 3 | 0 | 3 |
| CALHM1 | TMEM225 | 0.662666 | 3 | 0 | 3 |
| CALHM1 | ADIG | 0.644736 | 3 | 0 | 3 |
| CALHM1 | OSM | 0.630028 | 3 | 0 | 3 |
| CALHM1 | HORMAD2 | 0.61287 | 3 | 0 | 3 |
| CALHM1 | FHAD1 | 0.593083 | 4 | 0 | 3 |
| CALHM1 | OR10A3 | 0.580186 | 4 | 0 | 3 |
| CALHM1 | SATB2-AS1 | 0.579909 | 3 | 0 | 3 |
| CALHM1 | PRODH2 | 0.57298 | 3 | 0 | 3 |
| CALHM1 | SLC39A5 | 0.565368 | 3 | 0 | 3 |
| CALHM1 | TTR | 0.563308 | 3 | 0 | 3 |
| CALHM1 | CA1 | 0.551352 | 3 | 0 | 3 |
| CALHM1 | LINC00928 | 0.548573 | 3 | 0 | 3 |
| CALHM1 | LCE1E | 0.544588 | 4 | 0 | 3 |
| CALHM1 | SMPDL3B | 0.541501 | 4 | 0 | 3 |
| CALHM1 | C2orf83 | 0.533769 | 3 | 0 | 3 |
| CALHM1 | ZBTB20-AS1 | 0.522166 | 3 | 0 | 3 |
| CALHM1 | KIR2DL5A | 0.520837 | 4 | 0 | 3 |
| CALHM1 | C1orf167 | 0.514278 | 4 | 0 | 3 |
| CALHM1 | BRSK2 | 0.508951 | 5 | 0 | 3 |
For details and further investigation, click here
