| Full name: calcyon neuron specific vesicular protein | Alias Symbol: CALCYON|NSG3 | ||
| Type: protein-coding gene | Cytoband: 10q26.3 | ||
| Entrez ID: 50632 | HGNC ID: HGNC:17938 | Ensembl Gene: ENSG00000130643 | OMIM ID: 604647 |
| Drug and gene relationship at DGIdb | |||
Screen Evidence:
| |||
CALY involved pathways:
| KEGG pathway | Description | View |
|---|---|---|
| hsa04728 | Dopaminergic synapse |
Expression of CALY:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | CALY | 50632 | 219896_at | -0.1766 | 0.5763 | |
| GSE20347 | CALY | 50632 | 219896_at | -0.0474 | 0.3715 | |
| GSE23400 | CALY | 50632 | 219896_at | -0.1900 | 0.0000 | |
| GSE26886 | CALY | 50632 | 219896_at | 0.1603 | 0.2965 | |
| GSE29001 | CALY | 50632 | 219896_at | -0.0621 | 0.5308 | |
| GSE38129 | CALY | 50632 | 219896_at | -0.1460 | 0.0505 | |
| GSE45670 | CALY | 50632 | 219896_at | -0.0109 | 0.9314 | |
| GSE53622 | CALY | 50632 | 4873 | 0.0940 | 0.1399 | |
| GSE53624 | CALY | 50632 | 4873 | -0.0742 | 0.4182 | |
| GSE63941 | CALY | 50632 | 219896_at | 0.0203 | 0.9014 | |
| GSE77861 | CALY | 50632 | 219896_at | -0.0986 | 0.2777 | |
| GSE97050 | CALY | 50632 | A_33_P3318646 | 0.1496 | 0.4671 | |
| TCGA | CALY | 50632 | RNAseq | -4.8279 | 0.0000 |
Upregulated datasets: 0; Downregulated datasets: 1.
Survival by CALY expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of CALY:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | CALY | 50632 | 3 | 8 | 19 | |
| GSE20123 | CALY | 50632 | 3 | 9 | 18 | |
| GSE43470 | CALY | 50632 | 0 | 8 | 35 | |
| GSE46452 | CALY | 50632 | 1 | 11 | 47 | |
| GSE47630 | CALY | 50632 | 4 | 13 | 23 | |
| GSE54993 | CALY | 50632 | 8 | 2 | 60 | |
| GSE54994 | CALY | 50632 | 1 | 9 | 43 | |
| GSE60625 | CALY | 50632 | 0 | 0 | 11 | |
| GSE74703 | CALY | 50632 | 0 | 6 | 30 | |
| GSE74704 | CALY | 50632 | 3 | 4 | 13 | |
| TCGA | CALY | 50632 | 7 | 28 | 61 |
Total number of gains: 30; Total number of losses: 98; Total Number of normals: 360.
Somatic mutations of CALY:
Generating mutation plots.
Highly correlated genes for CALY:
Showing top 20/413 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| CALY | CDH24 | 0.826075 | 3 | 0 | 3 |
| CALY | KIR3DL2 | 0.816301 | 3 | 0 | 3 |
| CALY | TP53AIP1 | 0.795316 | 3 | 0 | 3 |
| CALY | KRTAP12-2 | 0.78285 | 3 | 0 | 3 |
| CALY | SLC26A5 | 0.767526 | 3 | 0 | 3 |
| CALY | SELPLG | 0.766954 | 3 | 0 | 3 |
| CALY | SPEG | 0.766434 | 3 | 0 | 3 |
| CALY | EVC2 | 0.761775 | 3 | 0 | 3 |
| CALY | ARHGEF33 | 0.76173 | 4 | 0 | 4 |
| CALY | APOBR | 0.75648 | 3 | 0 | 3 |
| CALY | OR2T33 | 0.755687 | 3 | 0 | 3 |
| CALY | RBM20 | 0.751756 | 4 | 0 | 4 |
| CALY | ELFN1 | 0.750975 | 3 | 0 | 3 |
| CALY | WDR93 | 0.750153 | 4 | 0 | 4 |
| CALY | KRTAP10-9 | 0.748479 | 3 | 0 | 3 |
| CALY | PAIP2 | 0.7418 | 3 | 0 | 3 |
| CALY | SERTAD1 | 0.731691 | 3 | 0 | 3 |
| CALY | MAGEC1 | 0.729339 | 4 | 0 | 4 |
| CALY | CCDC154 | 0.726341 | 5 | 0 | 5 |
| CALY | OR2AT4 | 0.724077 | 3 | 0 | 3 |
For details and further investigation, click here
