| Full name: poly(A) binding protein interacting protein 2 | Alias Symbol: PAIP2A | ||
| Type: protein-coding gene | Cytoband: 5q31.2 | ||
| Entrez ID: 51247 | HGNC ID: HGNC:17970 | Ensembl Gene: ENSG00000120727 | OMIM ID: 605604 |
| Drug and gene relationship at DGIdb | |||
Expression of PAIP2:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | PAIP2 | 51247 | 222984_at | -0.2570 | 0.5762 | |
| GSE26886 | PAIP2 | 51247 | 222984_at | -0.5091 | 0.0003 | |
| GSE45670 | PAIP2 | 51247 | 222984_at | -0.2470 | 0.0365 | |
| GSE63941 | PAIP2 | 51247 | 222983_s_at | 1.0715 | 0.0042 | |
| GSE77861 | PAIP2 | 51247 | 222984_at | -0.0303 | 0.8902 | |
| GSE97050 | PAIP2 | 51247 | A_23_P213754 | -0.2176 | 0.4462 | |
| SRP007169 | PAIP2 | 51247 | RNAseq | -0.6922 | 0.0407 | |
| SRP008496 | PAIP2 | 51247 | RNAseq | -0.6695 | 0.0004 | |
| SRP064894 | PAIP2 | 51247 | RNAseq | -0.3169 | 0.0139 | |
| SRP133303 | PAIP2 | 51247 | RNAseq | 0.3148 | 0.2158 | |
| SRP159526 | PAIP2 | 51247 | RNAseq | -0.1536 | 0.6054 | |
| SRP193095 | PAIP2 | 51247 | RNAseq | -0.3069 | 0.0118 | |
| SRP219564 | PAIP2 | 51247 | RNAseq | -0.4236 | 0.1031 | |
| TCGA | PAIP2 | 51247 | RNAseq | 0.0268 | 0.5729 |
Upregulated datasets: 1; Downregulated datasets: 0.
Survival by PAIP2 expression:
 |
| TCGA |
Note: Click image to view full size file.
Copy number change of PAIP2:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | PAIP2 | 51247 | 3 | 11 | 16 | |
| GSE20123 | PAIP2 | 51247 | 4 | 11 | 15 | |
| GSE43470 | PAIP2 | 51247 | 4 | 7 | 32 | |
| GSE46452 | PAIP2 | 51247 | 0 | 27 | 32 | |
| GSE47630 | PAIP2 | 51247 | 0 | 21 | 19 | |
| GSE54993 | PAIP2 | 51247 | 9 | 1 | 60 | |
| GSE54994 | PAIP2 | 51247 | 2 | 14 | 37 | |
| GSE60625 | PAIP2 | 51247 | 0 | 0 | 11 | |
| GSE74703 | PAIP2 | 51247 | 3 | 5 | 28 | |
| GSE74704 | PAIP2 | 51247 | 3 | 5 | 12 | |
| TCGA | PAIP2 | 51247 | 5 | 36 | 55 |
Total number of gains: 33; Total number of losses: 138; Total Number of normals: 317.
Somatic mutations of PAIP2:
Generating mutation plots.
Highly correlated genes for PAIP2:
Showing top 20/302 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| PAIP2 | TYW3 | 0.847194 | 3 | 0 | 3 |
| PAIP2 | NAA35 | 0.812994 | 3 | 0 | 3 |
| PAIP2 | CUL3 | 0.781505 | 3 | 0 | 3 |
| PAIP2 | LAMTOR3 | 0.772752 | 3 | 0 | 3 |
| PAIP2 | OPHN1 | 0.768587 | 3 | 0 | 3 |
| PAIP2 | STXBP3 | 0.766801 | 3 | 0 | 3 |
| PAIP2 | COPS5 | 0.75477 | 3 | 0 | 3 |
| PAIP2 | MRRF | 0.753363 | 3 | 0 | 3 |
| PAIP2 | DNAJC1 | 0.750704 | 3 | 0 | 3 |
| PAIP2 | RMND5B | 0.747825 | 3 | 0 | 3 |
| PAIP2 | COPS4 | 0.743973 | 3 | 0 | 3 |
| PAIP2 | CALY | 0.7418 | 3 | 0 | 3 |
| PAIP2 | RSL24D1 | 0.735971 | 3 | 0 | 3 |
| PAIP2 | EVC2 | 0.73574 | 3 | 0 | 3 |
| PAIP2 | CNOT6 | 0.73378 | 3 | 0 | 3 |
| PAIP2 | ARFGEF2 | 0.733594 | 3 | 0 | 3 |
| PAIP2 | TRIP4 | 0.732627 | 3 | 0 | 3 |
| PAIP2 | METTL14 | 0.729158 | 4 | 0 | 3 |
| PAIP2 | CHMP2A | 0.728837 | 3 | 0 | 3 |
| PAIP2 | TXNIP | 0.72613 | 3 | 0 | 3 |
For details and further investigation, click here
