| Full name: coiled-coil domain containing 28B | Alias Symbol: MGC1203|RP4-622L5.5 | ||
| Type: protein-coding gene | Cytoband: 1p35.2 | ||
| Entrez ID: 79140 | HGNC ID: HGNC:28163 | Ensembl Gene: ENSG00000160050 | OMIM ID: 610162 |
| Drug and gene relationship at DGIdb | |||
Expression of CCDC28B:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | CCDC28B | 79140 | 221912_s_at | 0.4654 | 0.1139 | |
| GSE20347 | CCDC28B | 79140 | 221912_s_at | 0.3025 | 0.0097 | |
| GSE23400 | CCDC28B | 79140 | 221912_s_at | 0.0308 | 0.5409 | |
| GSE26886 | CCDC28B | 79140 | 221912_s_at | 0.4630 | 0.0057 | |
| GSE29001 | CCDC28B | 79140 | 221912_s_at | 0.1864 | 0.4626 | |
| GSE38129 | CCDC28B | 79140 | 221912_s_at | 0.2301 | 0.0380 | |
| GSE45670 | CCDC28B | 79140 | 221912_s_at | 0.1558 | 0.3806 | |
| GSE53622 | CCDC28B | 79140 | 155845 | 0.4419 | 0.0000 | |
| GSE53624 | CCDC28B | 79140 | 155845 | 0.6056 | 0.0000 | |
| GSE63941 | CCDC28B | 79140 | 221912_s_at | -1.0339 | 0.0488 | |
| GSE77861 | CCDC28B | 79140 | 221912_s_at | -0.0181 | 0.9190 | |
| GSE97050 | CCDC28B | 79140 | A_23_P62764 | 0.0082 | 0.9806 | |
| SRP007169 | CCDC28B | 79140 | RNAseq | 1.5302 | 0.0403 | |
| SRP064894 | CCDC28B | 79140 | RNAseq | 1.7566 | 0.0000 | |
| SRP133303 | CCDC28B | 79140 | RNAseq | 0.0310 | 0.8506 | |
| SRP159526 | CCDC28B | 79140 | RNAseq | 1.1588 | 0.0528 | |
| SRP193095 | CCDC28B | 79140 | RNAseq | 0.5551 | 0.0001 | |
| SRP219564 | CCDC28B | 79140 | RNAseq | -0.1498 | 0.8069 | |
| TCGA | CCDC28B | 79140 | RNAseq | 0.4712 | 0.0011 |
Upregulated datasets: 2; Downregulated datasets: 1.
Survival by CCDC28B expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of CCDC28B:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | CCDC28B | 79140 | 1 | 5 | 24 | |
| GSE20123 | CCDC28B | 79140 | 1 | 4 | 25 | |
| GSE43470 | CCDC28B | 79140 | 6 | 4 | 33 | |
| GSE46452 | CCDC28B | 79140 | 5 | 1 | 53 | |
| GSE47630 | CCDC28B | 79140 | 8 | 3 | 29 | |
| GSE54993 | CCDC28B | 79140 | 1 | 1 | 68 | |
| GSE54994 | CCDC28B | 79140 | 11 | 2 | 40 | |
| GSE60625 | CCDC28B | 79140 | 0 | 0 | 11 | |
| GSE74703 | CCDC28B | 79140 | 4 | 3 | 29 | |
| GSE74704 | CCDC28B | 79140 | 0 | 0 | 20 | |
| TCGA | CCDC28B | 79140 | 10 | 20 | 66 |
Total number of gains: 47; Total number of losses: 43; Total Number of normals: 398.
Somatic mutations of CCDC28B:
Generating mutation plots.
Highly correlated genes for CCDC28B:
Showing top 20/285 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| CCDC28B | RASL10B | 0.821528 | 3 | 0 | 3 |
| CCDC28B | JSRP1 | 0.802214 | 3 | 0 | 3 |
| CCDC28B | CABP2 | 0.767681 | 3 | 0 | 3 |
| CCDC28B | ZNF646 | 0.766065 | 3 | 0 | 3 |
| CCDC28B | MAGEE1 | 0.742197 | 3 | 0 | 3 |
| CCDC28B | CLDN14 | 0.731692 | 4 | 0 | 4 |
| CCDC28B | TRIM17 | 0.730535 | 3 | 0 | 3 |
| CCDC28B | MAMLD1 | 0.729606 | 4 | 0 | 4 |
| CCDC28B | SHANK1 | 0.72944 | 4 | 0 | 4 |
| CCDC28B | MFSD6L | 0.729284 | 3 | 0 | 3 |
| CCDC28B | RHPN1 | 0.726613 | 4 | 0 | 4 |
| CCDC28B | FUZ | 0.725509 | 4 | 0 | 4 |
| CCDC28B | WNT9A | 0.724982 | 3 | 0 | 3 |
| CCDC28B | VRTN | 0.708115 | 3 | 0 | 3 |
| CCDC28B | NTNG2 | 0.706309 | 3 | 0 | 3 |
| CCDC28B | ERC2 | 0.70392 | 3 | 0 | 3 |
| CCDC28B | FAM181A | 0.697977 | 3 | 0 | 3 |
| CCDC28B | PTGER1 | 0.697973 | 4 | 0 | 3 |
| CCDC28B | GPR150 | 0.69565 | 3 | 0 | 3 |
| CCDC28B | KREMEN2 | 0.685502 | 6 | 0 | 4 |
For details and further investigation, click here
